CAS: 159453-24-4; N-Carbobenzoxy-S-Phenyl-L-Cysteine

相似化合物

34317-61-8 163705-28-0 85916-26-3

上下游产品

S-phenyl-L-cysteine benzyl chloroformate N-benzyloxycarbonyl-S-phenyl-L-cysteine methyl ester benzoic acid benzyl esterbenzyl [(2R,3S)-4-chloro-3-hydroxy-1-(phenylsulfanyl)-2-butanyl]carbamate benzyl [(1R)-1-[(2S)-2-oxiranyl]-2-(phenylsulfanyl)ethyl]carbamate benzyl [(2R,3R)-4-chloro-3-hydroxy-1-(phenylsulfanyl)-2-butanyl]carbamate

N-苄氧羰酰基-L-丝氨酸甲酯置于吡啶,4-二甲氨基吡啶,Sodium Tetrahydroborate体系中,用 甲醇,二氯甲烷,N,N-二甲基甲酰胺 用作溶剂,化学反应 32.0H,反应生成N-Z-S-苯基-L-半胱氨酸
参考文献:由(+)-顺式-(2R,3S)-3-羟基脯氨酸合成(-)-斯拉夫明
标题:由(+)-顺式-(2R,3S)-3-羟基脯氨酸合成(-)-斯拉夫明
摘要:从顺式-3-羟基脯氨酸衍生物1开始,已经实现了天然存在的吲哚izidine(-)-Slaframine 4的全合成,其中关键步骤是使用衍生自β-氨基砜5的二价阴离子的julia烯化反应.
Doi:10.1016/0040-4039(93)88117-2

专利信息

专利号:US-5846993-A
优先权日:1992-12-22
标题:HIV protease inhibitors
发明人：DRESSMAN BRUCE A; FRITZ JAMES E; KALDOR STEPHEN W; KALISH VINCENT J; REICH SIEGFRIED HEINZ; TATLOCK JOHN H; RODRIGUEZ MICHAEL J
权利人:AGOURON PHARMA
摘要:HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.

专利号:US-6271235-B1
优先权日:1992-12-22
标题:HIV protease inhibitors
发明人：DRESSMAN BRUCE A; FRITZ JAMES E; KALDOR STEPHEN W; KALISH VINCENT J; REICH SIEGFRIED HEINZ; RODRIGUEZ MICHAEL J; SHEPHERD TIMOTHY A; TATLOCK JOHN H; JUNGHEIM LOUIS NICKOLAUS
权利人:AGOURON PHARMA
摘要:HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.

专利号:US-5527829-A
优先权日:1994-05-23
标 题 :HIV protease inhibitors
发明人：KALISH VINCENT J
权利人:AGOURON PHARMA
摘要:HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.