Trans-10,11-Dibromodibenzosuberenone 反应 0.05H,以91%的收率获得5-二苯并环庚烯酮 参考文献:Rapid And Efficient Debromination Of Vic-Dibromides With Vcl3/indium System 标题:Rapid And Efficient Debromination Of Vic-Dibromides With Vcl3/indium System 摘要:研究发现,$vcl_3$/in体系是一种新的去溴化方法,能够在温和条件下快速高效地将多种邻二溴化物转化为相应的烯烃.这种新方法具有高度的化学选择性,能够容忍多种官能团,如氯,溴,氟,酮,酯,羧基和甲氧基等. Doi:10.5012/jkcs.2018.62.4.275
专利号:WO-9517903-A1 优先权日:1993-12-28 标 题:Modular design and synthesis of oxazolone-derived molecules 发明人:HOGAN JOSEPH C JR; CASEBIER DAVID; FURTH PAUL; TU CHENG 权利人:ARQULE PARTNERS L P; HOGAN JOSEPH C JR; CASEBIER DAVID; FURTH PAUL; TU CHENG 摘要:The design and synthesis of novel oxazolone-derived molecular modules and the use of the modules in the construction of new molecules and fabricated materials is disclosed. The new molecules and fabricated materials are molecular recognition agents useful in the design and synthesis of drugs, and have applications in separations and materials science.
专利号:EP-4428168-A1 优先权日:2023-03-08 标 题 :Polyurethane/oligomeric urethane synthesis method by radiation 发明人:AKBULUT HÜSEYIN; ÇEL KBA SENA; ENADA SEHER; U AKLI MÜGE; DEM RBAY DUYGU 权利人:CHT TURKEY KIMYA SANAYI VE TICARET A S 摘要:In particular, the invention relates to the synthesis of radiation-curable polyurethane/oligomeric urethane dispersions of anionic and cationic characters, containing neutralization techniques characterized by the selection of counter ions as monomers and/or agents which can be polymers acting as promoters under radiation, to a radiation polyurethane/oligomeric urethane synthesis method that enables the creation of radiation curable binder systems without using cosolvents, surfactants, emulsifiers, defoamers, stabilizers and additives, wherein all components of the radiation-curable binder systems can be polymerized.
专利号:US-5831095-A 优先权日:1995-09-26 标题 :Synthesis of 5-aminocarbonyl-5H-dibenzo a,d!cyclohepten-5,10-imine 发明人:GONZALEZ JAVIER; CARROLL F IVY 权利人:RES TRIANGLE INST 摘要:A powerful new anti-convulsant and anti-ischemic pharmaceutical, 5-aminocarbonyl-5H-dibenzo a,d!cycloheptene-5,10-imine is prepared according to a novel synthesis which converts the starting material, commercially available dibenzosubernone to ADCI without the use of chromatographic purification, hazardous reagents or extreme conditions. The starting material is converted to the corresponding imine through ammonia exposure, and directly converted with acetone cyanohydrin in the presence of sodium cyanide to a 5-amino, 5-cyanocycloheptene intermediate. The intermediate is cyclized using bromine, followed by a reduction of the bromine-carbon bond using sodium cyanoborohydride. The target compound is obtained through selective hydrolysis. An overall yield of 46 percent or better is obtained.
专利号:CN-105492891-B 优先权日:2013-08-05 标 题:Synthesis of aggregation-induced luminescence material and its synthesis method
专利号:CN-105492891-A 优先权日:2013-08-05 标题:Synthesis of aggregation-induced luminescence material and its synthesis method
专利号:US-7320993-B1 优先权日:1997-12-17 标题 :Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents 发明人:BIEDERMANN ELFI; HASMANN MAX; LOESER ROLAND; RATTEL BENNO; REITER FRIEDEMANN; SCHEIN BARBARA; SEIBEL KLAUS; VOGT KLAUS; WOSIKOWSKI KATJA; SCHEMAINDA ISABEL 权利人:ASTELLAS DEUTSCHLAND GMBH 摘要:The invention relates to new pyridylalkane, alkene, and alkine acid amides substituted with an aryl and/or heteroaryl residue according to the general formula (I), with a saturated or one or several-fold unsaturated hydrocarbon residue in the carboxylic acid group, methods for the synthesis of these compounds, medicaments containing these and their production as well as their therapeutic use, especially as cytostatic agents and immunosuppressive agents, for example in the treatment or prevention of various types of tumors and control of immune reactions such as autoimmune diseases.
摘要:Ito, S.; Morita, N., Science of Synthesis, (2010) 45, 476. 摘要:Yorimitsu, H., Science of Synthesis Knowledge Updates, (2010) 3, 17. 摘要:U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals., NX#02244