CAS: 29548-30-9; Farnesylacetate

上下游产品

acetic acid methyl ester farnesyl benzoate farnesol acetic anhydrideAcetic acid (2E,6E)-11-methoxy-3,7,11-trimethyl-10-phenylselanyl-dodeca-2,6-dienyl ester 10,11-epoxyfarnesyl acetate 6,7;10,11-diepoxy-3,7,11-trimethyl-2-dodecen-1-ol acetate (2E,6E)-9-((R)-3,3-Dimethyl-oxiranyl)-3,7-dimethyl-nona-2,6-dien-1-ol

金合欢醇,乙酸酐置于manganese(II) Iodide,萘,Lithium体系中,用 四氢呋喃 用作溶剂,化学反应 1.17H,以77%的收率获得3,7,11-三甲基-2,6,10-十二烷三烯-1-醇乙酸酯
参考文献:醇与酰氯或酸酐的高活性锰介导酰化
标题:醇与酰氯或酸酐的高活性锰介导酰化
摘要:为了进一步探索高活性锰 (Mn*) 的实际用途,用 Mn* 处理各种醇,在没有任何额外催化剂的情况下,将所得配合物与酰氯和/或乙酸酐偶联.随后的反应在温和的条件下顺利进行,提供了相应的 O-酰化产物,分离产率非常好至极好.
Doi:10.1055/s-0036-1590973

专利信息

专利号:WO-2024013633-A1
优先权日:2022-07-11
标 题 :Process for the synthesis of vitamin k2
发明人：SHASTRI MAYANK; BAIKAR MRUNALI H; VORA PARIN K; BNS RAJU
权利人:SYNERGIA LIFE SCIENCES PVT LTD
摘要:The present disclosure relates to the synthesis of Vitamin K2 bearing varying prenyl side chains. The synthesis comprises the reaction of phenyl sulfone of tert-butyl dimethyl silyl (TBDMS) protected mono prenyl menadiol with prenyl halides bearing varying prenyl units in the presence of the phase transfer catalyst followed by reductive desulphonation to yield TBDMS ether of Vitamin K2. The TBDMS ether is then oxidized in the presence of chromium trioxide and periodic acid to yield the corresponding Vitamin K2.

专利号:US-9464021-B2
优先权日:2013-11-01
标题 :Method of preparation of stereospecific quinone derivatives
发明人：MEHTA DILIP S; MOHAN PRIYA; SHASTRI MAYANK; REID TED
权利人:MEHTA DILIP S; MOHAN PRIYA; SHASTRI MAYANK; REID TED
摘要:The description provides processes for the regio and stereospecific synthesis of polyprenylatedquinone derivatives, such as Vitamin K1, K2 and Ubiquinone, exploiting dithioacetals, especially 1,3-dithiane, mediated Umpolung chemistry which works along a new concept “Inhibiting resonance delocalization (IRD)â€? to overcome isomerization generated due to delocalization of allyliccarbanion on the Ï€-electron cloud of an allylic systems by the conventional synthesis.

专利号:US-2021114953-A1
优先权日:2018-06-08
标 题:Synthesis of e,e-farnesol, farnesyl acetate and squalene from farnesene via farnesyl chloride
发明人：FISHER KARL JOSEPH; WOOLARD FRANK XAVIER
权利人:AMYRIS INC
摘要:The present disclosure provides methods for preparing polyunsaturated hydrocarbons, such as E,E-farnesol, farnesyl acetate and squalene, by base catalyzed addition of a dialkylamine to a 3-methylene-1-alkene, such as farnesene. The present disclosure also provides compositions including one more farnesene derivatives prepared using the disclosed methods.

专利号:US-12194020-B2
优先权日:2017-12-22
标 题:Reversing baldness through cannabinoid receptor activation
发明人：POSTREL RICHARD
权利人:POSTREL RICHARD
摘要:This invention reverses male pattern baldness by shocking dormant hair follicles out of their androgen induced hibernation phase back to the active hair-growing anagenic phase. The invention integrates two functions: 1) It blocks synthesis of compounds holding the follicles in the telogenic/hibernating phase and 2) It stimulates synthesis of compounds animating the hair-growing/anagenic phase in the follicular activity cycle. One preferred embodiment comprises an enzyme inhibitor blocking the conversion of testosterone to dihydrotestosterone (DHT), a flavonoid simultaneously increasing synthesis of prostaglandins alternative to prostaglandin D2, and a selected cannabinoid compound stimulating restore the hair follicle to its normal growth cycle. This novel trimodal therapy restores the hair follicles to their normal cycling processes and maintains these restorative properties so long as this rebalance in maintained.

专利号:US-2014243404-A1
优先权日:2010-09-14
标题 :Unique halogen-induced cyclizations, reagents therefor, and compounds produced thereby
发明人：SNYDER SCOTT ALAN; TREITLER DANIEL S; BRUCKS ALEXANDRIA P; GOLLNER ANDREAS; CHIRIAC MARIA I; WRIGHT NATHAN E; PFLUEGER JASON J; BREAZZANO STEVEN P
权利人:SNYDER SCOTT ALAN; TREITLER DANIEL S; BRUCKS ALEXANDRIA P; GOLLNER ANDREAS; CHIRIAC MARIA I; WRIGHT NATHAN E; PFLUEGER JASON J; BREAZZANO STEVEN P; UNIV COLUMBIA
摘要:This disclosure is related to halonium compounds useful for cyclization of polyenes, alkenoic acids, and alkenyl alkyl ethers, and halogenation of aromatic compounds. The synthesis of such halonium compounds, compounds made using such halonium compounds, and synthesis of natural compounds, including decalins, using the halonium compounds is also disclosed. A representative halonium compound of the disclosure is:

专利号:US-7439027-B2
优先权日:1995-01-13
标题 :Method for modulating process mediated by farnesoid activated receptors
发明人：EVANS RONALD M; FORMAN BARRY M; WEINBERGER CARY A
权利人:SALK INST FOR BIOLOGICAL STUDI; LIGAND PHARM INC; USA
摘要:Farnesyl pyrophosphate, the metabolically active form of farnesol, is a key precursor in the synthesis of cholesterol, carotenoids, steroid hormones, bile acids and other molecules involved in cellular growth and metabolism. A nuclear receptor has been identified that is transcriptionally activated by farnesol and related molecules. This novel signaling pathway can be modulated by the use of key metabolic intermediates (or analogs and/or derivatives thereof) as transcriptional regulatory signals.