CAS: 89-35-0; 3,5-Dihydroxy-2-Naphthoic Acid

该化合物是分子式C11H10O4的有机化合物,在3和5位置上,以两个氢氧基组替代的环状环状系统,在2位置上,以碳酸组替代的环状环状系统;该化合物的特点是其室温状态固态,显示出一种白色到非白晶状的外表;在水和酒精等极地溶剂中可溶解,但非冰溶剂中却不易溶解;氢氧基组的存在有助于其形成氢结,影响其与其他分子的再活动与互动;3,5-二氢氧基-2-甲苯丙基苯乙酸酸,经常研究其在制药,染料和染色剂方面的潜在应用,并因其抗氧化性特性而成为生物化学剂;此外,它可能在各种生物过程中发挥作用,使其在化学和生物化学研究中引起兴趣.

结构式图片

相似化合物

3147-58-8 92-70-6 185989-39-3

物理性质

MSDS等安全信息

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号185989-39-3 3,5-二羟基-2-萘甲酸甲酯 | CAS号114608-54-7 2-hydroxy-8-met... | CAS号84-43-5 2-羟基-11H-苯并[a]咔...

合成工艺路线路线简述

    Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于氢氧化钾,水体系中,化学反应生成 3,5-二羟基-2-萘羧酸
    参考文献:Hosaeus,Chemische Berichte,1893,Vol. 26,P. 671
    标题:Hosaeus,Chemische Berichte,1893,Vol. 26,P. 671

    海关参考信息

    专利信息


    专利号:US-9217012-B2
    优先权日:2009-04-08
    标题 :Inhibitors of protein tyrosine phosphatases
    发明人：ZHANG ZHONG-YIN; ZHANG SHENG
    权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
    摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

    专利号:US-9879022-B2
    优先权日:2014-04-04
    标题:Bicyclic-fused heteroaryl or aryl compounds
    发明人：TRZUPEK JOHN DAVID; LEE KATHERINE LIN; BUNNAGE MARK EDWARD; HAN SEUNGIL; HEPWORTH DAVID; LOVERING FRANK ELDRIDGE; MATHIAS JOHN PAUL; PAPAIOANNOU NIKOLAOS; PIERCE BETSY SUSAN; STROHBACH JOSEPH WALTER; WRIGHT STEPHEN WAYNE; ZAPF CHRISTOPH WOLFGANG; GAVRIN LORI KRIM; LEE ARTHUR; ANDERSON DAVID RANDOLPH; CURRAN KEVIN JOSEPH; DEHNHARDT CHRISTOPH MARTIN; SAIAH EDDINE; GOLDBERG JOEL ADAM; WANG XIAOLUN; HUANG HORNG-CHIH; VARGAS RICHARD; LOWE MICHAEL DENNIS; PATNY AKSHAY
    权利人:PFIZER
    摘要:Compounds, tautomers and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula Ia, n nas defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

    专利号:CN-115612114-A
    优先权日:2021-07-14
    标 题:Method and application of copolymer film and its enzymatic self-assembly synthesis

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    主要参考文献


    1: Monaghan DT, Irvine MW, Costa BM, Fang G, Jane DE. Pharmacological modulation of NMDA receptor activity and the advent of negative and positive allosteric modulators. Neurochem Int. 2012 Sep;61(4):581-92. doi: 10.1016/j.neuint.2012.01.004. Epub 2012 Jan 17. Review.
    2: Costa BM, Irvine MW, Fang G, Eaves RJ, Mayo-Martin MB, Skifter DA, Jane DE, Monaghan DT. A novel family of negative and positive allosteric modulators of NMDA receptors. J Pharmacol Exp Ther. 2010 Dec;335(3):614-21. doi: 10.1124/jpet.110.174144. Epub 2010 Sep 21.

    合成参考文献


    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
    摘要:Schafer, E. W., Jr., W. A. Bowles Jr., and J. Hurlbut. 1983. The acute oral toxicity and repellency and hazard potential of 998 chemicals to one or more species of wild and domestic birds. Archives of Environmental Contamination and Toxicology 12:355-382.
    摘要:Schafer, E. W., Jr., and W. A. Bowles Jr. 1985. Acute oral toxicity and repellency of 933 chemicals to house and deer mice. Archives of Environmental Contamination and Toxicology 14:111-129. https://www.aphis.usda.gov/ws/nwrc/chem-effects-db/S_schafer851.pdf
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