CAS: 100-43-6; 4-Vinylpyridine

该化合物是一种多用途有机化合物,其特征是用苯丙胺环替换成一个正辛基组;这种结构具有适合聚合和功能化的再活性,在合成特殊聚合物,粘合剂和涂层方面很有价值;其乙烯基组可与苯乙烯或丙烯酸等单体共同聚合,增强热稳定性和化学抗药性等物质特性;此外,4-苯丙烯因其能够进行核细胞替代和交叉反应,因此是制药和农用化学中间体的前体;其高纯度和一贯性能使它成为需要精确分子修改的研究和工业应用的首选.

结构式图片

欧盟法规

REACH注册ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号108-89-4 4-甲基吡啶 | CAS号50-00-0 甲醛 | CAS号872-85-5 4-吡啶甲醛 | CAS号2065-66-9 甲基三苯基碘化 | CAS号5344-27-4 4-乙醇基吡啶 | CAS号34064-35-2 4-(oxiran-2-yl)... | CAS号82769-08-2 poly{Ru(2,2'-bi... | CAS号16887-00-6 氯离子 | CAS号28148-48-3 4-(2-氯乙基)-吡啶 | CAS号105163-71-1 4-(2-butylsulfa... | CAS号109573-05-9 (2-吡啶-4-基-乙基)氨基甲酸叔丁酯 | CAS号107266-08-0 卡伏曲林 | CAS号109688-58-6 4-(4-pyridin-4-... | CAS号106047-17-0 4-(吡啶-4-基)苯甲酸甲酯 | CAS号102878-73-9 4-吡啶-4-基丁酸 | CAS号105163-65-3 4-(2-°Ctylsulfi... | CAS号536-75-4 4-乙基吡啶 | CAS号120690-80-4 4-吡啶丙醛 | CAS号7704-34-9 硫磺

合成工艺路线路线简述

  • 合成目标产物 4-Vinylpyridine 主要起始原料 4-Bromopyridine Hydrochloride And Pinacol Vinylboronate
  • (文献来源)合成步骤主要原料 4-Bromopyridine Hydrochloride 和 Pinacol Vinylboronate
4-碘吡啶置于甲醇,Copper(L) Iodide,四(三苯基膦)钯,氢气,Potassium Hydroxide,三甲胺体系中,用 乙酸乙酯 用作溶剂,20.0~110.0 °C,100.0 Kpa 条件下,反应 1.66H,反应生成4-乙烯基吡啶
参考文献:Design And Characterization Of A Heterocyclic Electrophilic Fragment Library For The Discovery Of Cysteine-Targeted Covalent Inhibitors
标题:Design And Characterization Of A Heterocyclic Electrophilic Fragment Library For The Discovery Of Cysteine-Targeted Covalent Inhibitors
摘要:通过半胱氨酸反应性和水稳定性测试,对亲电性小杂环片段库进行了表征,结果表明它们有潜力作为共价战斗头.
Doi:10.1039/c8Md00327K

专利信息


专利号:US-7514559-B2
优先权日:2004-03-22
标题 :Catalyst for synthesis of 2- and 4-picolines
发明人:DUTTA PASHUPATI; ROY SUBHASH CHANDRA; ROY SHYAM KISHORE; GOSWAMI TARUN KANTI
权利人:COUNCIL SCIENT IND RES
摘要:The present invention provides a catalyst composite for the synthesis of 2- and 4-picolines and a process for the preparation thereof and use thereof for the synthesis of 2- and 4-Picolines.

专利号:US-4895922-A
优先权日:1988-05-05
标 题 :Low temperature synthesis of polyesteramides
发明人:OGATA NAOYA
权利人:GOODYEAR TIRE & RUBBER
摘要:This invention disclosed a process for the synthesis of polyesteramides. By utilizing the phosphorus containing catalyst systems of the present invention, such polyesteramides can be synthesized at relatively low temperatures. The present invention specifically discloses a process for the synthesis of a polyesteramide which comprises polymerizing at least one diamine, at least one diol, and at least one dicarboxylic acid in the presence of (1) at least one acid acceptor; (2) at least one halogenated organic compound; and (3) at least one phosphorus containing compound selected from the group consisting of (a) triphenylphosphine, (b) triphenylphosphine oxide, (c) triphenylphosphine sulfide, (d) polymeric agents having pendant diphenylphosphine groups, (e) silicon-phosphorus compositions which contain at least one divalent oxygen atom which is bonded directly to a tetravalent silicon atom and a trivalent or pentavalent phosphorus atom; (f) compounds with the structural formula (C 6 H 5 ) 3 P=N-R, wherein R is a hydrogen atom or an alkyl group containing from 1 to 10 carbon atoms; and (g) compounds with the structural formula (C 6 H 5 )PR 1 R 2 wherein R 1 and R 2 can be the same or different, wherein R 1 is selected from the group consisting of alkyl groups containing from 1 to 10 carbon atoms and phenyl groups, and wherein R 2 is an alkyl group containing from 1 to 10 carbon atoms.

专利号:WO-03031376-A1
优先权日:2001-10-12
标 题 :Solid phase synthesis of substituted 1,5-benzodiazepine-2-one and 1,5-benzothiazepine-2-one
发明人:MORTON GEORGE C; SALVINO JOSEPH M; LABAUDINIERE RICHARD F; HERPIN TIMOTHY F
权利人:AVENTIS PHARMA INC; MORTON GEORGE C; SALVINO JOSEPH M; LABAUDINIERE RICHARD F; HERPIN TIMOTHY F
摘要:A solid phase synthetic method for making substituted 1,5-benzodiazepine-2-one or 1,5-benzothiazepine-2-one. The method is useful for synthesis of large numbers of compounds through automated parallel synthesis or combinatorial library generation and is thus important to rapid discovery or new therapeutic agents containing the base structure of 1,5-benzodiazepine-2-one or 1,5-benzothiazepine-2-one.

专利号:US-7138526-B1
优先权日:1999-06-15
标 题 :Solid phase synthesis of n,n-disubstituted diazacycloalkylcarboxy derivatives
发明人:HERPIN TIMOTHY F; MORTON GEORGE C; SALVINO JOSEPH M
权利人:AVENTIS PHARMA INC
摘要:A method for the solid phase synthesis of N,N-disubstituted diazacycloalkylcarboxy derivatives of general formula (I) and (II) is claimed. Examples include piperazine-2-carboxamide. The method is applicable to the synthesis or large combinatorial libraries

专利号:US-6127515-A
优先权日:1997-11-18
标 题:Functionalized resin for the synthesis of amides and peptides
发明人:MANFRE FRANCO; VANASSE BENOIT J; LABAUDINIERE RICHARD F; MORTON GEORGE C
权利人:AVENTIS PHARM PROD INC
摘要:This invention is directed to a functionalized amino resin of formula ##STR1## wherein S is a solid support; R is H or alkyl; A is ##STR2## Y is OH or OCOR 1 ; and R 1 is aliphatic or aromatic which is useful for the solid phase synthesis of amides, peptides and hydroxamic acids.

专利号:US-2023119068-A1
优先权日:2020-02-13
标题:Methods for rapid synthesis of pyranoanthocyanins
发明人:ZHU XIAOYI; STRAATHOF NICOLE; MIYAGUSUKU-CRUZADO GONZALO; GIUSTI M MONICA; CANO ISRAEL GARCIA; JIMENEZ-FLORES RAFAEL
权利人:OHIO STATE INNOVATION FOUNDATION
摘要:The present disclosure provides methods for the rapid synthesis of pyranoanthocyanins.
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合成参考文献


参考文献:10.1007/s12031-010-9333-1
摘要:Yoon JS, Yang H, Kim SH, Sung SH, Kim YC. Limonoids from Dictamnus dasycarpus Protect Against Glutamate-induced Toxicity in Primary Cultured Rat Cortical Cells. Journal of Molecular Neuroscience. 2010 Feb 13;42(1):9–16. doi: 10.1007/s12031-010-9333-1.
参考文献:10.1016/j.chemosphere.2011.06.087
摘要:Sahiner N, Ozay O, Aktas N. Aromatic organic contaminant removal from an aqueous environment by p(4-VP)-based materials. Chemosphere. 2011 Oct;85(5):832–8. doi: 10.1016/j.chemosphere.2011.06.087.
参考文献:10.1021/la2022165
摘要:Wang HL, Sun Q, Chen M, Miyake J, Qian DJ. Layer-by-layer assembly and characterization of multilayers of a manganese porphyrin linked poly(4-vinylpyridinium) derivative and poly(styrenesulfonic acid-o-maleic) acid. Langmuir. 2011 Aug 16;27(16):9880–9. doi: 10.1021/la2022165.
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