CAS: 134-85-0; 4-Chlorobenzophenone(Chunks Or Pellets Or Flake)

上下游产品

(4-chlorophenyl)phenylmethanol benzoyl chloride chlorobenzene 1-(4-chloro-phenyl)-1-phenyl-propane-1,2-diol 1-(4-chloro-phenyl)-1-phenyl-2-[2]pyridyl-ethanol (4-chloro-phenyl)-phenyl-[3]pyridyl-methanol (4-chloro-phenyl)-phenyl-[2]pyridyl-methanol 2-(4-chlorophenyl)-2-phenyl-1,3-dithiolane

1-氯-4-(1-苯基乙基)苯置于偶氮二异丁腈,氧气,Nickel Dibromide体系中,用 氯仿 用作溶剂,化学反应 60.0H,以58%的收率获得4-氯二苯甲酮
参考文献:Aibn在存在双氧的情况下引发了苄基sp 3 C H和c C键的官能化
标题:Aibn在存在双氧的情况下引发了苄基sp 3 C H和c C键的官能化
摘要:通过aibn / O 2催化剂体系实现了sp 3 C H键的官能化和c C键的裂解,在温和的反应条件下提供了一系列的二苯甲酮.机理研究表明,过氧化物中间体参与了这一转变,在二苯基甲烷的情况下,Sp 3 C C键通过过氧化物重排而断裂,这可能提供了一种断裂相对较强的c C键并被应用的新方法.更一般的c C键活化.
Doi:10.1016/j.Tetlet.2020.152806

专利信息

专利号:US-10865390-B2
优先权日:2018-02-12
标 题 :Alcohol dehydrogenase mutant and application thereof in synthesis of diaryl chiral alcohols
发明人：NI YE; ZHOU JIEYU; XU GUOCHAO; WANG YUE
权利人:UNIV JIANGNAN
摘要:The present disclosure discloses an alcohol dehydrogenase mutant and application thereof in synthesis of diaryl chiral alcohols, and belongs to the technical field of bioengineering. The alcohol dehydrogenase mutant of the present disclosure has excellent catalytic activity and stereoselectivity, and may efficiently catalyze the preparation of a series of chiral diaryl alcohols in R- and S-configurations. By coupling alcohol dehydrogenase of the present disclosure to glucose dehydrogenase or formate dehydrogenase, the synthesis of chiral diaryl alcohol intermediates of various antihistamines may be achieved. Compared with the prior art, a method for preparing diaryl chiral alcohols through asymmetric catalytic reduction using the alcohol dehydrogenase of the present disclosure has the advantages of simple and convenient operation, high substrate concentration, complete reaction and high product purity, and has great industrial application prospects.

专利号:US-10822593-B2
优先权日:2018-02-12
标 题:Alcohol dehydrogenase mutant and application thereof in synthesis of diaryl chiral alcohols
发明人：NI YE; ZHOU JIEYU; XU GUOCHAO; WANG YUE
权利人:UNIV JIANGNAN
摘要:The present disclosure discloses an alcohol dehydrogenase mutant and application thereof in synthesis of diaryl chiral alcohols, and belongs to the technical field of bioengineering. The alcohol dehydrogenase mutant of the present disclosure has excellent catalytic activity and stereoselectivity, and may efficiently catalyze the preparation of a series of chiral diaryl alcohols in R- and S-configurations. By coupling alcohol dehydrogenase of the present disclosure to glucose dehydrogenase or formate dehydrogenase, the synthesis of chiral diaryl alcohol intermediates of various antihistamines may be achieved. Compared with the prior art, a method for preparing diaryl chiral alcohols through asymmetric catalytic reduction using the alcohol dehydrogenase of the present disclosure has the advantages of simple and convenient operation, high substrate concentration, complete reaction and high product purity, and has great industrial application prospects.

专利号:US-11078465-B2
优先权日:2018-02-12
标题:Alcohol dehydrogenase mutant and application thereof in synthesis of diaryl chiral alcohols
发明人：NI YE; WANG YUE; DAI WEI; XU GUOCHAO; ZHOU JIEYU
权利人:UNIV JIANGNAN
摘要:The present disclosure discloses an alcohol dehydrogenase mutant and application thereof in synthesis of diaryl chiral alcohols, and belongs to the technical field of bioengineering. The alcohol dehydrogenase mutant of the present disclosure has excellent catalytic activity and stereoselectivity, and may efficiently catalyze the preparation of a series of chiral diaryl alcohols in R- and S-configurations. By coupling alcohol dehydrogenase of the present disclosure to glucose dehydrogenase or formate dehydrogenase, the synthesis of chiral diaryl alcohol intermediates of various antihistamines may be achieved. Compared with the prior art, a method for preparing diaryl chiral alcohols through asymmetric catalytic reduction using the alcohol dehydrogenase of the present disclosure has the advantages of simple and convenient operation, high substrate concentration, complete reaction and high product purity, and has great industrial application prospects.

专利号:US-9920160-B2
优先权日:2014-09-03
标题 :Method for synthesis of polymer containing multiple epoxy groups
发明人：GAO CHAO; ZHENG YAOCHEN; PENG LI; CAI SHENGYING; WENG ZHULIN
权利人:UNIV ZHEJIANG
摘要:A method for a synthesis of a polymer containing multiple epoxy groups includes steps of: under protection of nitrogen or argon, with a photosensitive free radical initiator under an ultraviolet light irradiation, initiating a mixture of a dithiol compound and alkynyl glycidyl ether or other alkynyl-containing compounds to proceed a thiol-yne polymerization, so as to obtain the polymer. The number of the epoxy groups is able to be adjusted through changing a type of a dithiol monomer, a mixing ratio of the dithiol monomer, and a mixing ratio between the alkynyl glycidyl ether and other alkynyl compounds. The present invention has advantages of: fast reaction, convenient process, easy post-processing, a large number of the epoxy groups, and adjustable and controllable content. The obtained polymer has a wide potential application in fields of coating, adhesive, ink, encapsulating material, resin for composite material, additive, high performance material, function material, and so on.

专利号:WO-2018011378-A1
优先权日:2016-07-13
标 题 :Method for the synthesis of a polyolefin by means of romp in the presence of a ruthenium-based catalyst
发明人：PINAUD JULIEN; CHEMTOB ABRAHAM; HEROGUEZ VALÉRIE; PLACET EMELINE; SAUVANIER DAVID; LACROIX-DESMAZES PATRICK
权利人:CENTRE NATIONAL DE LA RECHERCHE SCIENT (CNRS); UNIV MONTPELLIER; UNIV BORDEAUX; BORDEAUX INP; UNIV HAUTE ALSACE; AXLR SATT DU LANGUEDOC ROUSSILLON; ENSCM
摘要:The present invention relates to a method for the synthesis of a polyolefin by means of a photoinitiated ROMP reaction involving a cyclic olefin in the presence of a ruthenium-based catalyst of formula (I), in which the catalyst is generated in situ under UV radiation from an inactive ruthenium complex of formula [RuCl 2 (L)] 2 and an imidazoli(ni)um salt of formula (III).

专利号:US-8212056-B2
优先权日:2008-06-30
标 题 :Ligands for transition-metals and methods of use
发明人：KWONG FUK YEE; SO CHAU MING
权利人:KWONG FUK YEE; SO CHAU MING; UNIV HONG KONG POLYTECHNIC
摘要:The present invention relates to indolyl phosphine ligands, and methods of making such ligands utilizing phenyl hydrazines and aryl ketones as the starting material. The present invention further includes uses of the ligands in the synthesis of pharmaceuticals, materials, and agriculture.