CAS: 2199-43-1; Ethyl 1H-Pyrrole-2-Carboxylate

相似化合物

1003-29-8 634-97-9 3284-51-3

上下游产品

4-溴-1H-吡咯-2-羧酸乙酯 Ethyl 4-Bromo-1H-Pyrrole-2-Carboxylate 433267-55-1
吡咯-2-羧酸 Pyrrole-2-Carboxyl Acid 634-97-9

吡咯-2-羧酸置于氯化亚砜体系中,用 乙醇,氯仿,N,N-二甲基甲酰胺,甲苯 用作溶剂,化学反应生成吡咯-2-羧酸乙酯
参考文献:Aromatic Heterocycle Compounds Having Hiv Integrase Inhibiting Activities
标题:Aromatic Heterocycle Compounds Having Hiv Integrase Inhibiting Activities
摘要:公式(i)的化合物:其中x是羟基,保护羟基或可选择取代的氨基;Y是-coora,其中ra是氢或酯基,-conrbrc,其中rb和rc分别独立地是氢或酰胺基,可选择取代的芳基或可选择取代的杂环芳基;而a1是可选择取代的杂环芳基;前提是化合物中y和/或a1为可选择取代的吲哚-3-基团的化合物被排除在外,其互变体,前药,药学上可接受的盐或水合物对整合酶具有抑制活性.

专利信息

专利号:US-7112671-B2
优先权日:2000-08-30
标 题 :Non-symmetric tripyrranes in the synthesis of novel macrocycles
发明人：MODY TARAK D; GALANTER JOSHUA
权利人:PHARMACYCLICS INC
摘要:The present invention provides certain non-symmetric tripyrranes; that is, tripyrranes that do not contain a mirror plane of symmetry perpendicular to the plane containing the tripyrrane. Further, the invention includes texaphyrin compounds and sapphyrin compounds, as well as other polypyrrolic macrocycles, prepared using tripyrranes of Formula I as a precursor. These macrocycles are characterized by a tripyrrolic portion of the macrocyclic ring having substituents that cause the heterocycle to lack a plane of symmetry perpendicular to the plane of the macrocycle.

专利号:US-2003232800-A1
优先权日:2000-08-30
标 题:Non-symmetric tripyrranes in the synthesis of novel macrocycles

专利号:US-2008281105-A1
优先权日:2005-01-18
标题:Novel Quinolinium Salts and Derivatives
发明人：MACDONALD JAMES E; HYSELL MICHELLE K; YU DEHUA; LI HENRY; WONG-STAAL FLOSSIE
权利人:IMMUSOL INC
摘要:The present invention relates generally to the synthesis of novel quinolinium salts and derivative compounds. Such salts and compounds are useful for inhibiting the growth of cancer cells.

专利号:US-6984734-B2
优先权日:2002-02-26
标 题 :Cyclo[n]pyrroles and methods thereto
发明人：SESSLER JONATHAN L; SEIDEL DANIEL; BOLZE FREDERIC R; KOEHLER THOMAS
权利人:UNIV TEXAS
摘要:The present invention provides an oxidative coupling procedure that allows efficient synthesis of novel cyclo[n]pyrrole macrocycles. Therefore, the present invention provides cyclo[n]pyrroles where n is 6, 7, 8, 9, 10, 11, or 12, and derivatives, multimers, isomers, and ion and neutral molecule complexes thereof as new compositions of matter. A protonated form of cyclo[n]pyrrole displays a gap of up to 700 nm between strong Soret and Q-like absorption bands in the electronic spectrum, demonstrating no significant ground state absorption in the visible portion of the electronic spectrum. Uses of cyclo[n]pyrroles as separation media, nonlinear optical materials, information storage media and infrared filters are provided.

专利号:WO-0217925-A1
优先权日:2000-08-30
标题 :Non-symmetric tripyrrannes in the synthesis of novel macrocycles

专利号:IT-PD20090224-A1
优先权日:2009-07-29
标题 :CHEMICAL SYNTHESIS OF NEW HETEROCYCLIC PHOTOCHEMIOTHERAPY AGENTS, WITH ANTIPROLIFERATIVE ACTIVITY INCLUDING THE NEOPLASTIC ONE