乙酸苯酯置于lewis Acid体系中,用 硝基苯 作为反应溶剂,化学反应生成 2'-甲氧基苯乙酮 参考文献:Infrared Study Of Polysubstitution Effects In Benzophenones And Acetophenones: Contribution Of Inter And Intracycle Interaction Mechanism 标题:Infrared Study Of Polysubstitution Effects In Benzophenones And Acetophenones: Contribution Of Inter And Intracycle Interaction Mechanism 摘要: DOI:10.1016/0584-8539(81)80141-9
专利号:US-6274383-B1 优先权日:1997-12-15 标题:Methods for synthesizing libraries of dihydro-quinazolinones 发明人:GAO YUN 权利人:SEPRACOR INC 摘要:Synthetic methods for solution and solid-phase synthesis of combinatorial libraries of dihydro-quinazolinones, including synthesis of 2,3-dihydro-3-alkoxy-4(1H)-quinazolinones or 2,3-dihydro-3-hydroxy-4(1H)-quinazolinones via the Lewis-acid catalyzed reaction of an appropriate 2-aminobenzamide with an aldehyde at ambient temperature performed on a solid support or in solution.
专利号:US-4152517-A 优先权日:1977-10-19 标题:Synthesis of 6-(2-hydroxyphenyl)-3(2H)-pyridazinones from trihalocarbinols 发明人:LEVINSON SIDNEY H; MENDELSON WILFORD L 权利人:SMITHKLINE CORP 摘要:A new synthesis for the preparation of 6-(2-hydroxyphenyl)-3-pyridazinones whose key reaction is cyclizing a 1,1,1-trihalo-2-hydroxy-4-(2-hydroxyphenyl)-1-butanone with hydrazine. 6-(2-Hydroxyphenyl)-3-pyridazinones are important intermediates for preparing medicinally active compounds.
专利号:US-2023068064-A1 优先权日:2019-12-02 标题 :Process for synthesis of a 2-thioalkyl pyrimidine 发明人:HONG JUNBAE 权利人:FMC CORP 摘要:A method for preparing a compound of Formula 1 and compounds therefrom, comprising treating a compound of Formula 2 with a compound of Formula 3 and reacting the resulting intermediate of Formula 4 with a compound of Formula 5 (or a salt thereof). The compound of Formula 1, prepared by the above method, can be used to prepare a compound of Formula 8 wherein R2, R3, R4, m and r are as defined in the specification.
专利号:US-2022145179-A1 优先权日:2020-11-12 标题 :Synthesis of aryl 1-(methoxymethyl) vinyl ketones and their use as inhibitors of mild steel corrosion 发明人:MAZUMDER MOHAMMAD ABU JAFAR; ALI SHAIKH ASROF; ODEWUNMI NURUDEEN; ALHARBI BADER; ALJEABAN NORAH; CHEN TAO; BALHARTH SALEM 权利人:SAUDI ARABIAN OIL CO; UNIV KING FAHD PET & MINERALS 摘要:Methods for preparing alkenylphenone corrosion inhibiting compositions may include providing an arylacetone and reacting the arylacetone with formaldehyde in the presence of a strong base catalyst. Corrosion inhibiting compositions may include an alkenylphenone, which may be prepared by a method including providing an arylacetone and reacting the arylacetone with formaldehyde in the presence of a strong base catalyst. Methods of inhibiting corrosion of a steel surface of an oilfield equipment component may include contacting the steel surface with an aqueous solution comprising a corrosion inhibitor. The corrosion inhibitor may include a composition containing an alkenylphenone prepared by reacting an arylacetone with formaldehyde in the presence of a strong base catalyst.
专利号:US-9328061-B2 优先权日:2012-03-01 标题:Simple organic molecules as catalysts for practical and efficient enantioselective synthesis of amines and alcohols 发明人:HOVEYDA AMIR H; SILVERIO DANIEL L; PILYUGINA TATIANA; TORKER SEBASTIAN; ROBBINS DANIEL 权利人:TRUSTEES BOSTON COLLEGE 摘要:The present invention provides organic molecules and methods thereof for reactions between organoboron reagents and double bonds, such as imines or carbonyls, to stereoselectively provide chiral products including amines and alcohols, entities useful for the preparation of biologically active molecules.
专利号:US-2023160000-A1 优先权日:2015-09-28 标 题:Synthesis of novel disulfide linker based nucleotides as reversible terminators for dna sequencing by synthesis