CAS: 62855-02-1; (R)-(1,2,3,4-Tetrahydroisoquinolin-3-yl)Methanol

相似化合物

18881-17-9 243858-66-4 103733-65-9

上下游产品

formaldehyd L-phenylalanine (S)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid, phenylmethylester ethyl (S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate hydr°Chloride (S)-4-Benzyloxycarbonylamino-5-((S)-3-hydroxymethyl-3,4-dihydro-1H-isoquinolin-2-yl)-5-oxo-pentanoic acid methyl ester 2-[2-Benzyloxycarbonylamino-3-((S)-3-hydroxymethyl-3,4-dihydro-1H-isoquinolin-2-yl)-3-oxo-propyl]-malonic acid dimethyl ester N-[2-(3-hydroxymethyl-3,4-dihydro-1H-isoquinolin-2-yl)-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]-2-nitro-benzenesulfonamideN-[2-(3-hydroxymethyl-3,4-dihydro-1H-isoquinolin-2-yl)-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]-2-nitro-benzenesulfonamide tert-butyl (3S)-3-(hydroxymethyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate

(R)-(+)-1,2,3,4-四氢异喹啉-3-羧酸置于lithium Aluminium Tetrahydride体系中,化学反应生成 R-1,2,3,4-四氢异喹啉-3-基-甲醇
参考文献:Enantioselective Hydrogenation Of Functionalized Ketones. Synthesis And Application Of New Chiral Aminophosphine-Phosphinite Ligands
标题:Enantioselective Hydrogenation Of Functionalized Ketones. Synthesis And Application Of New Chiral Aminophosphine-Phosphinite Ligands
摘要:手性新氨基膦-膦酸酯(ampp 1-7)已被合成并成功应用于二氢-4,4-二甲基-2,3-呋喃二酮8,N-苄基苯甲酰甲胺9和乙基丙酮酸10的对映选择性氢化,所得到的羟基产物的对映体过量分别高达97%,95%和80%.
DOI:10.1055/s-1998-1858