CAS: 1124-63-6; 3-Cyclohexylpropan-1-Ol

该化合物是一种饱和的脂性酒精,配有三碳丙醇链的环己醇组,该化合物具有中度极性,因为氢氧组具有中度,在有机合成和特殊化学应用中作为中间体有用,其环己烷有助于增强稳定性和亲脂性,而主要酒精功能允许进一步衍生,如酯化或氧化.该产品通常用于生产香气,药品和农用化学品,其平衡的疏水性和反应性是有利的.它与一系列溶剂相容,在标准处理条件下表现出良好的热稳定性.

结构式图片

相似化合物

701-97-3 4441-57-0 4442-79-9

上下游产品

3-Phenyl-1-propanol ethyl 3-cyclohexylpropanoate 3-Phenylpropenol 2-cyclohexylmethyl-3-hydroxy-butyric acid ethyl ester ethyl-cyclohexane (3-bromopropyl)cyclohexane 3-cyclohexylpropanal phenyl-carbamic acid-(3-cyclohexyl-propyl ester)

合成工艺路线路线简述

    3-苯基丙-2-烯-1-醇置于1,4-二氧六环,Copper Chromite体系中,270.0~280.0 °C,19.61 Mpa 条件下,反应生成3-环已基-1-丙醇
    参考文献:Studies On Lignin And Related Compounds. Lxxi. The Course Of Formation Of Native Lignin In Spruce Buds1
    标题:Studies On Lignin And Related Compounds. Lxxi. The Course Of Formation Of Native Lignin In Spruce Buds1
    摘要:
    Doi:10.1021/ja01246A050

    海关参考信息

    专利信息


    专利号:US-5753726-A
    优先权日:1995-12-20
    标 题:Synthesis of modified epoxy resins for cathodic electrodeposition with catalyst deactivation and diol modification
    发明人:REUTER HARDY; JOUCK WALTER; OTT GUENTHER
    权利人:BASF LACKE & FARBEN
    摘要:Epoxy resins for preparing water-dispersible binders for cathodic electrodeposition coating materials, the epoxy resin being preparable by reacting a) polyepoxides having at least one glycidyl group per molecule b) and, optionally, up to 60% by weight, based on the overall epoxy resin reaction product, of aliphatic and/or alicyclic hydroxy compounds having preferably two or on average less than two hydroxyl groups per molecule and a molecular weight of less than 9000 g/mol, c) in the presence of a catalyst consisting of neutral metal salts, such as alkali metal salts and alkaline earth metal salts, zinc salts and nickel salts of tetrafluoroboric, tetrachloroboric, hexafluoro- antimonic,hexachloroantimonic,hexafluorophosphoric, perchlorate and periodic acid, and d) adding a deactivating agent which prevents the epoxy groups reacting further or effectively reduces the rate of such reaction as soon as the phenolic hydroxyl groups have already substantially reacted and at least 0.6% by weight of epoxy groups are still present, based on the overall weight of the epoxy resin reaction product.\\!

    专利号:US-5637757-A
    优先权日:1995-04-11
    标 题 :One-pot synthesis of ring-brominated benzoate compounds
    发明人:HILL JOHN E; FAVSTRITSKY NICOLAI A; MAMUZIC RASTKO I; BHATTACHARYA BHABATOSH
    权利人:GREAT LAKES CHEMICAL CORP
    摘要:A method of preparing tetrabromobenzoate compounds from tetrabromophthalic anhydride by reacting tetrabromophthalic anhydride with alcohol in the presence of a decarboxylation catalyst. The reaction may be carried out in an excess of alcohol, or with a near stoichiometric amount of alcohol by performing the reaction in an inert solvent.

    专利号:WO-2012163936-A1
    优先权日:2011-05-31
    标 题 :Process for the synthesis of benzotriazoles useful as uv-filters
    发明人:PRESCHEL MICHAEL; ROEDER MICHAEL; SCHLIFKE-POSCHALKO ALEXANDER; ZHANG KESHENG
    权利人:DSM IP ASSETS BV; PRESCHEL MICHAEL; ROEDER MICHAEL; SCHLIFKE-POSCHALKO ALEXANDER; ZHANG KESHENG
    摘要:The invention relates to an improved process for the manufacture of novel benzotriazoles as well to novel benzotriazoles obtained by the novel process. This novel economical process provides products in high purity and yields.

    专利号:US-9388345-B2
    优先权日:2012-07-03
    标题:Hydrocarbon synthesis methods, apparatus, and systems
    发明人:MCNEFF CLAYTON V; MCNEFF LARRY C; NOWLAN DANIEL THOMAS; YAN BINGWEN; GREUEL PETER G
    权利人:SARTEC CORP
    摘要:Embodiments of the invention include apparatus and systems for hydrocarbon synthesis and methods regarding the same. In an embodiment, the invention includes a process for creating a hydrocarbon product stream comprising reacting a reaction mixture in the presence of a catalyst inside of a reaction vessel to form a product mixture, the reaction mixture comprising a carbon source and water. The temperature inside the reaction vessel can be between 450 degrees Celsius and 600 degrees Celsius and the pressure inside the reaction vessel can be above supercritical pressure for water. In an embodiment, the invention includes an extrusion reactor system for creating a hydrocarbon product stream. The temperature inside the extrusion reactor housing between 450 degrees Celsius and 600 degrees Celsius. Pressure inside the reaction vessel can be above supercritical pressure for water. Other embodiments are also included herein.

    专利号:WO-2010115869-A1
    优先权日:2009-04-03
    标 题 :Propofol phosphonyl derivatives, synthesis, and use in long acting formulations
    发明人:GONNISSEN YVES RENE JOHANNA PAUL
    权利人:SEPS PHARMA N V; GONNISSEN YVES RENE JOHANNA PAUL
    摘要:This invention relates to compounds represented by the structural formula (I), and the salts and stereoisomers thereof, wherein: - L is a linker selected from the group consisting of -(CH 2 ) P -O-, a single bond, formula (IA), -(CH 2 ) 1-8 -O-X(O)-, and - p is an integer from 1 to 8, - each R 3 and each R 4 is independently selected from the group consisting of C 1-20 alkyl, C 3-12 alkyl, C 3-12 cycloalkyl-C 1-4 alkyl, saturated heterocyclyl and saturated heterocyclyl-C 1-4 alkyl, and - X and Y are each independently C or S(O), - Z is selected from the group consisting of O, S(O) and NR 5 , - W is selected from the group consisting of halogen, OH, S(O)H and O - M + wherein M + is a monovalent cation; and - R 5 is selected from the group consisting of hydrogen and C 1-10 alkyl. These compounds are useful pharmaceutical agents with improved oral bioavailability.

    专利号:WO-2011114184-A1
    优先权日:2010-03-15
    标题 :Amides of heterocyclic compounds as trpa1 inhibitors
    发明人:CHAUDHARI SACHIN SUNDARLAL; KUMAR SUKEERTHI; THOMAS ABRAHAM; PATIL NISHA PARAG; KADAM ASHOK BHAUSAHEB; WAGHMARE NAYAN TATERAO; KHAIRATKAR-JOSHI NEELIMA; MUKHOPADHYAY INDRANIL
    权利人:GLENMARK PHARMACEUTICALS SA; CHAUDHARI SACHIN SUNDARLAL; KUMAR SUKEERTHI; THOMAS ABRAHAM; PATIL NISHA PARAG; KADAM ASHOK BHAUSAHEB; WAGHMARE NAYAN TATERAO; KHAIRATKAR-JOSHI NEELIMA; MUKHOPADHYAY INDRANIL
    摘要:Amides of heterocyclic compounds as Transient Receptor Potential subfamily A (TRPA) modulators are provided In particular, compounds described herein are useful for treating or preventing diseases, conditions and/ or disorders modulated by TRPA1 (Transient Receptor Potential subfamily A, member 1) Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPA1. (I).
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    合成参考文献


    摘要:Aitken, R. A., Science of Synthesis Knowledge Updates, (2018) 3, 304.
    摘要:Aitken, R. A.; Boubalouta, Y., Science of Synthesis Knowledge Updates, (2013) 4, 137.
    摘要:Kleoff, M.; Omoregbee, K.; Zimmer, R., Science of Synthesis Knowledge Updates, (2018) 4, 214.
    摘要:Casano, G.; Ouari, O., Science of Synthesis, (2021) , 47.
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