CAS: 60871-84-3; Nickel(Ii) Trifluoromethanesulfonate

专利信息

专利号:US-7951961-B2
优先权日:2006-07-07
标题:Enantioselective synthesis of pyrrolidines substituted with flavones, and intermediates thereof
发明人：SIVAKUMAR MEENAKSHI; SHUKLA MANOJ; JADHAV PRAMOD KUMAR; BORHADE AJIT
权利人:PIRAMAL LIFE SCIENCES LTD
摘要:The present invention relates to an enantioselective synthesis of (+)-trans enantiomer of pyrrolidines substituted with flavones, represented by Formula 1 or salts thereof, which are inhibitors of cyclin dependant kinases and can be used for treatment of proliferative disorders such as cancer n nwherein Ar has the meaning as indicated in the claims.

专利号:WO-2020194337-A4
优先权日:2019-03-28
标题:A process for the asymmetric synthesis of sitagliptin intermediate
发明人：PUNJI BENUDHAR; SENTHILKUMAR BEERAN; VENKATA RAMANA CHEPURI
权利人:COUNCIL SCIENT IND RES
摘要:The present invention relates to a process for the asymmetric synthesis of compound of Formula 2. wherein, R1 is selected from the group consisting of C(O)R or C(O)OR; R is selected from the group consisting of CH3, ethyl, isopropyl and tert-butyl R2 is selected from the group consisting of straight or branched, substituted or unsubstituted C1-C10 alkyl, substituted or unsubstituted aryl groups. More particularly, the present invention relates to an asymmetric hydrogenation of compound of Formula 2 by using new catalyst system, which provides desired product formation in a very cost effective way.

专利号:US-12234203-B2
优先权日:2020-03-12
标 题:Process for the synthesis of cannabidiol and intermediates thereof
发明人：ANAND RADHIKA; SHARMA SUMIT; SINGH CHAM PANKAJ; GANNEDI VEERANJANEYULU; KUMAR MUKESH; PRATAP SINGH VARUN; PRAKASH RAHUL VISHAV; ASREY VISHWAKARMA RAM; PAL SINGH PARVINDER
权利人:COUNCIL OF SCIENT AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN OF T; COUNCIL OF SCIENT AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN OF S
摘要:The present invention relates to process for the preparation of cannabidiol (A) from the coupling of (D) and (E) through the intermediates (C) and (D) starting from compound (B). The invention further relates to the novel compounds (B), (C), (D) and (E) and reagents used in this process. More specifically, this invention provides the manufacturing of Cannabidiol (A) in milligram to gram or kilogram scale.

专利号:WO-2017030685-A1
优先权日:2015-08-14
标题 :One-pot synthesis of anhydropentitol mono- and diethers
发明人：STENSRUD KENNETH
权利人:ARCHER DANIELS MIDLAND CO
摘要:A process for preparing anhydropentitol mono- and diethers from C 5 sugar alcohols is described. The process involves performing in a single reaction vessel consolidated reactions that a) cyclize dehydratively a linear C 5 sugar alcohol and b) etherify a resulting anhydropentitol. Each of the reactions is catalyzed by a very low amount of a water-tolerant Lewis acid catalyst relative to the starting sugar-alcohol. Depending on the reaction conditions, the synthesis method is efficient, selective and affords good yields of mono- and diethers. The anhydropentiol ethers can serve as renewable substitute precursors of petroleum incumbents for use in the making of surfactants and plasticizers.

专利号:WO-2017100402-A1
优先权日:2015-12-11
标 题 :One-pot synthesis of anhydropentitol esters from pentitols, catalyzed by water-tolerant lewis acids
发明人：STENSRUD KENNETH
权利人:ARCHER DANIELS MIDLAND CO
摘要:A procedure for preparing anhydropentitol mono, di, and tri esters is described. The process is performed in a single vessel and involves sequential dehydrative cyclization and carboxylic acid acylation steps. Each step is catalyzed by low loadings of a water-tolerant Lewis acid catalyst. The method of synthesis is efficacious and depending on the reaction condition, generates modest to high yields of the target mono-, di-, and triesters. The esters can be practical surrogates of incumbent petroleum materials of similar structure used for surfactants and plasticizers.

专利号:US-2017121258-A1
优先权日:2014-04-10
标题 :Synthesis of r-glucosides, sugar alcohols, reduced sugar alcohols, and furan derivatives of reduced sugar alcohols
发明人：SANBORN ALEXANDRA; BINDER THOMAS P
权利人:ARCHER DANIELS MIDLAND CO
摘要:Disclosed herein are methods for synthesizing 1,2,5,6-hexanetetrol (HTO), 1,6 hexanediol (HDO) and other reduced polyols from C5 and C6 sugar alcohols or R glycosides. The methods include contacting the sugar alcohol or R-glycoside with a copper catalyst, most desirably a Raney copper catalyst with hydrogen for a time, temperature and pressure sufficient to form reduced polyols having 2 to 3 fewer hydoxy groups than the starting material. When the starting compound is a C6 sugar alcohol such as sorbitol or R-glycoside of a C6 sugar such as methyl glucoside, the predominant product is HTO. The same catalyst can be used to further reduce the HTO to HDO.