专利号:US-2023173450-A1 优先权日:2020-04-28 标题:Automated chemical synthesis platform 发明人:CRONIN LEROY; MEHR HESSAM; CRAVEN MATTHEW; LEONOV ARTEM 权利人:UNIV GLASGOW COURT 摘要:The invention provides a method for controlling an automated chemistry platform using synthetic procedures written in natural language. The method uses natural language processing (NLP) techniques to interpret a synthetic procedure written in natural scientific language and extracts a machine-readable instruction set comprising the distinct operations necessary for carrying out the synthesis on an automated chemical synthesis platform. The method optionall also includes the step of executing the machine-readable instruction set on an automated chemical synthesis platform.
专利号:US-6515091-B2 优先权日:2000-05-01 标 题 :Anionic vinyl/dicarboxylic acid polymers and uses thereof 发明人:SANDERS JOHN LARRY; KIMMERLY JAMES MICHAEL; MAZO GRIGORY 摘要:Biodegradable anionic polymers are disclosed which include recurring polymeric subunits preferably made up of vinylic and dicarboxylic monomers such as vinyl acetate or vinyl alcohol and maleic anhydride, itaconic anhydride or citraconic anhydride, or combinations thereof. Free radical polymerization is used in the synthesis of the polymers, which are then hydrolyzed to replace ester groups with alcohol groups. The polymers may be complexed with ions and/or mixed with fertilizers or seed to yield agriculturally useful compositions. The preferred products of the invention may be applied foliarly, to seeds, to fertilizer, or to the earth adjacent growing plants in order to enhance nutrient uptake by the plants.
专利号:US-12064740-B2 优先权日:2018-03-06 标题 :Networked reaction systems 发明人:CRONIN LEROY 权利人:CHEMIFY LTD 摘要:The present invention provides a system for performing reactions, where the system comprises a plurality of synthesisers that are in communication via a communal reporting platform. A synthesiser is programmed for the automated synthesis of one or more chemical or biological reactions, and the synthesiser comprises a reaction vessel which is supplied by a reagent delivery system, an analytical system for analysing a reaction, and a controller for managing the reagent delivery system and the analytical system, and for communication with the reporting platform. Also provided are methods for performing a plurality or reactions using the system.
专利号:US-2022095622-A1 优先权日:2019-05-13 标题 :Application of Compounds Inhibiting Synthesis of Very Long Chain Fatty Acids in Preventing and Treating Microbial Pathogens and Method Thereof
专利号:US-6596831-B2 优先权日:2000-05-01 标 题:Anionic vinyl/dicarboxylic acid polymers and uses thereof 发明人:SANDERS JOHN LARRY; KIMMERLY JAMES MICHAEL; MAZO GRIGORY 摘要:Biodegradable anionic polymers are disclosed which include recurring polymeric subunits preferably made up of vinylic and dicarboxylic monomers such as vinyl acetate or vinyl alcohol and maleic anhydride, itaconic anhydride or citraconic anhydride, or combinations thereof. Free radical polymerization is used in the synthesis of the polymers, which are then hydrolyzed to replace ester groups with alcohol groups. The polymers may be complexed with ions and/or mixed with fertilizers or seed to yield agriculturally useful compositions. The preferred products of the invention may be applied foliarly, to seeds, to fertilizer, or to the earth adjacent growing plants in order to enhance nutrient uptake by the plants.
专利号:WO-2024144124-A1 优先权日:2022-12-30 标 题:Recombinant microorganisms for producing fucosyllactose and method of fucosyllactose production using same 发明人:JO HEEGEUN; PARK BUSOO; YOON JIHEE; KIM JINHA; HAN EUNJIN 权利人:SAMYANG CORP 摘要:The present invention relates to: recombinant microorganisms having 2'-fucosyllactose production activity by having an exogenous enzyme related to GDP-L-fucose synthesis introduced thereinto and overexpressing the enzyme; a method for producing 2'-fucosyllactose by using the recombinant microorganisms; and a composition comprising the recombinant microorganisms.
[参考文献]: Allan J Alla, Et Al. Selective Capture Of Glycoproteins Using Lectin-Modified Nanoporous Gold Monolith. J Chromatogr A. 2015 Dec 4:1423:19-30. [参考文献]: Anita Leocadio Freitas-Mesquita, Et Al. Leishmania Amazonensis: Characterization Of An Ecto-Pyrophosphatase Activity. Exp Parasitol. 2014 Feb:137:8-13. [参考文献]: Barry J Bowman, Et Al. The Pmr Gene, Encoding A Ca2+-Atpase, Is Required For Calcium And Manganese Homeostasis And Normal Development Of Hyphae And Conidia In Neurospora Crassa. Eukaryot Cell. 2012 Nov;11(11):1362-70. [参考文献]: Graziela Ribeiro Batista, Et Al. Effect Of Chemical Activation Of 10% Carbamide Peroxide Gel In Tooth Bleaching. Eur J Esthet Dent. 2013 Spring;8(1):104-17. [参考文献]: Hong-Min Meng, Et Al. Activatable Two-Photon Fluorescence Nanoprobe For Bioimaging Of Glutathione In Living Cells And Tissues. Anal Chem. 2014 Dec 16;86(24):12321-6.
合成参考文献
摘要:EHP, Environmental Health Perspectives., 10(95), 1975 [] 参考文献:10.1074/jbc.m405043200 摘要:Wright TG, Tsai J, Jia Z, Elliott BE. Inhibition by Copper(II) Binding of Hepatocyte Growth Factor (HGF) Interaction with Its Receptor Met and Blockade of HGF/Met Function. Journal of Biological Chemistry. 2004 Jul;279(31):32499–506. doi: 10.1074/jbc.m405043200. 参考文献:10.2116/analsci.31.997 摘要:See WP, Heng LY, Nathan S. Highly Sensitive Aluminium(III) Ion Sensor Based on a Self-assembled Monolayer on a Gold Nanoparticles Modified Screen-printed Carbon Electrode. Analytical Sciences. 2015 Oct 10;31(10):997–1003. doi: 10.2116/analsci.31.997. 参考文献:10.1007/s00216-018-1092-9 摘要:Emaus MN, Clark KD, Hinners P, Anderson JL. Preconcentration of DNA using magnetic ionic liquids that are compatible with real-time PCR for rapid nucleic acid quantification. Analytical and Bioanalytical Chemistry. 2018 Apr 28;410(17):4135–44. doi: 10.1007/s00216-018-1092-9.