CAS: 58551-83-0; 2,4,6-Trifluorobenzaldehyde

上下游产品

CAS号372-38-3 1,3,5-三氟苯 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号111991-19-6 2-(2,4,6-triflu... | CAS号220227-80-5 2,4,6-三氟苯乙腈 | CAS号885520-26-3 4,6-二氟-1H-吲唑 | CAS号853654-95-2 1,3,5-trifluoro... | CAS号887567-79-5 4,6-二氟-3-碘-1H-吲唑 | CAS号377084-09-8 3-(2,4,6-TRIFLU...

1,3,5-三氟苯置于正丁基锂,甲酸乙酯体系中,用 四氢呋喃 作为反应溶剂,以79 %的收率获得产物2,4,6-三氟苯甲醛
参考文献:异氰酸酯诱导的氮杂氟环化对大环化合物和笼的多重后修饰
标题:异氰酸酯诱导的氮杂氟环化对大环化合物和笼的多重后修饰
摘要:我们通过氮杂氟化环化(adfc)将官能团引入带有氟取代基的二维和三维超分子支架中,这使得能够使用容易获得的异氰酸酯进行多步超分子化学,从而实现自组装大环和笼的外部化学空间的功能化.使用二位异氰酸酯,Adfc 可用于从超分子实体创建交联膜.
DOI:10.1002/anie.202318362

专利信息

专利号:US-10745342-B2
优先权日:2018-07-05
标 题 :Synthesis method of 2,4,6-trifluorobenzylamine
发明人：YUAN QILIANG; QIAN JIE; LAI XIN; CHEN HAIFENG; CHEN YINHAO; WANG CHAO
权利人:ZHEJIANG ZHONGXIN FLUORIDE MAT CO LTD; SHAOXING ZHONGKE BAIYUN CHEMICAL TECH CO LTD
摘要:The disclosure provides a synthesis method of 2,4,6-trifluorobenzylamine, belonging to the technical field of chemical synthesis. The synthesis method is characterized by comprising the following steps: (1) allowing pentachlorobenzonitrile as a raw material to undergo fluoridation reaction with a fluoridation agent based on 2,4,6-trifluoro-3,5-dichlorobenzonitrile as a solvent to obtain 2,4,6-trifluoro-3,5-dichlorobenzonitrile; (2) hydrogenating the obtained 2,4,6-trifluoro-3,5-dichlorobenzonitrile with hydrogen in the presence of organic carboxylic acid, based, on palladium carbon as a catalyst to obtain 2,4,6-trifluoro-3,5-dichlorobenzylamine; and (3) hydrogenating the obtained 2,4,6-trifluoro-3,5-dichlorobenzylamine with hydrogen in a solvent in the presence of a catalyst to obtain 2,4,6-trifluorobenzylamine. The synthesis method has the advantages of low raw material cost, short reaction steps, high reaction yield, good product purity simple operation and the like, and is suitable for industrial production.

专利号:US-6822092-B2
优先权日:2000-06-12
标 题:Expanded porphyrins and a method for synthesis thereof
发明人：OSUKA ATSUHIRO
权利人:JAPAN SCIENCE & TECH AGENCY
摘要:Novel meso-aryl substituted expanded porphyrins comprising of alternate arrangement of more than six of pyrrole units bridged by a methine group whose hydrogen is substituted with Ar-group; and their synthetic method. Ar-group is either a 2,6-substituted phenyl group which can possess a substituent at the other 3, 4, and 5 positions, or 9-anthryl group which can possess a substituent at the other positions of the anthracence, or a cyclohexyl group which can possess a substituent at the other positions of the cyclohexyl group. The substituents at the 2 and 6 positions mentioned above can be selected independently from halogen atom or lower alkyl group of carbon number 1 to 4, substituents at 3-5 positions, 9-anthryl group and cyclohexyl group can be selected independently from the group consisting of substituted or non-substituted alkyl of carbon number 5 or 6, substituted or non-substituted aryl group, besides above mentioned substituents at 2 and 6 positions. Each Ar-group can be different.

专利号:WO-2005068451-A2
优先权日:2003-12-31
标 题:Methods for the synthesis of dictyostatin and derivatives and analogues thereof, stereochemical characterisation, novel dictyostatin compounds and uses thereof and synthetic intermediates

专利号:EP-4073056-B1
优先权日:2019-12-13
标 题:Process for the preparation of lasmiditan and of a synthesis intermediate
发明人：CREMONESI GIUSEPPE; INVERNIZZI CHRISTIAN; SADA MARA; FELICIANI LAZZARO; BERTOLINI GIORGIO
权利人:OLON SPA

专利号:US-12428380-B2
优先权日:2023-06-28
标 题 :Compounds
发明人：BANISTER SAMUEL; JORGENSEN WILLIAM; TAN JINLONG; WHISH LACHLAN
权利人:Psylo Pty Ltd
摘要:The present disclosure relates generally to compounds, their methods of synthesis, and their use in the treatment of mental illness or central nervous system disorders.

专利号:US-2020207702-A1
优先权日:2018-07-05
标 题:Synthesis method of 2,4,6-trifluorobenzylamine