CAS: 100-55-0; 3-Pyridinemethanol

上下游产品

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烟酰胺置于c24H20Cln2Opru,Potassium Tert-Butylate,氢气体系中,用 四氢呋喃 用作溶剂,110.0 °C,1.42 Mpa 条件下,反应 36.0H,以63%的收率获得3-吡啶甲醇
参考文献:在ru催化下伯酰胺和环状二肽的选择性氢化.
标题:在ru催化下伯酰胺和环状二肽的选择性氢化.
摘要:报道了钌(II)催化的具有挑战性的伯酰胺和环状二肽分别选择性氢化为其相应的伯醇和氨基醇.氢化反应在温和的生态友好条件下进行,并且可以扩大规模.
Doi:10.1039/d0Cc04550K

专利信息

专利号:US-8354116-B2
优先权日:2007-06-18
标题 :Bifunctional synthetic molecules
发明人：CARTER STEPHEN G; PATEL KANU; ZHU ZHEN; QIAO LIXIN
权利人:BIOCHEMICS INC; CARTER STEPHEN G; PATEL KANU; ZHU ZHEN; QIAO LIXIN
摘要:The synthesis and use of bifunctional molecules to improve the topical and transdermal delivery efficiency of various types of therapeutic agents or agents designed to promote the transdermal delivery of those therapeutic agents either into the skin tissue or into the systemic circulation. Three major classes of molecules are covalently joined as bifunctional substances; chemical vasodilators, passive dermal penetration enhancers and therapeutic or diagnostic drugs. Chemical vasodilators may be delivered into the skin to increasing the blood flow in a tissue that has compromised circulation or they may be used as part of a delivery vehicle to promote the delivery of the drug. Passive dermal penetration enhancers are those chemicals that promote the passive penetration of drugs and other chemicals through the stratum corneum and epidermis of the skin tissue. Drugs and diagnostic agents are the third group of chemicals that are candidates for the linkage of molecules.