CAS: 131860-33-8; Azoxystrobin

欧盟法规

[欧盟农药活性物质

上下游产品

(E)-methyl 2-[2-(6-chloropyrimidin-4-yloxy)phenyl]-3-methoxy-propenoate salicylonitrile 1-methyl-pyrrolidin-2-one ethylene glycol2-(2-(6-(2-cyanophenoxy)pyrimidin-4-yloxy)phenyl)acetic acid methyl ester methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate 4,6-pyrimidinediol 2-(6-hydroxypyrimidin-4-yloxy)benzonitrile

邻氯苯乙酸置于sodium,Potassium Carbonate,Copper(II) Oxide,Sodium Hydroxide体系中,用 水,N,N-二甲基甲酰胺 用作溶剂,化学反应 14.0H,反应生成嘧菌酯
参考文献:一种提高嘧菌酯转化率的方法
标题:一种提高嘧菌酯转化率的方法
摘要:本发明公开了一种提高嘧菌酯转化率的方法,包括如下步骤:制备(E)‑2‑[2‑(6‑氯嘧啶‑4‑基氧基)苯基]‑3‑甲氧基丙烯酸甲酯;制备邻羟基苯甲腈;将(E)‑2‑[2‑(6‑氯嘧啶‑4‑基氧基)苯基]‑3‑甲氧基丙烯酸甲酯,邻羟基苯甲腈,碳酸钾和氯化亚酮按30:35:50:1.1的摩尔比混合并溶于二甲基甲酰胺中制得混合产物;将制得的混合产物加热并保温后进行过滤,经减压蒸馏,冷却,析出晶体,过滤洗涤,干燥后制得嘧菌酯,在现有技术的基础上,对嘧菌酯的合成进行改进,从而有效提升嘧菌酯的收率,有效提升嘧菌酯的原料(E)‑2‑[2‑(6‑氯嘧啶‑4‑基氧基)苯基]‑3‑甲氧基丙烯酸甲酯和邻羟基苯甲腈在制备嘧菌酯的过程中的转化率,从而提升了嘧菌酯的生产效益.

专利信息

专利号:WO-2022146324-A1
优先权日:2020-12-29
标 题 :Synthesis of pyrimidine-4(lh)-one derivatives from new hydrazineylidene
发明人：SARIPINAR EMIN; BURCU HILAL JANSET; KEKEÇMUHAMMED HÃœSEYIN; TAPERA MICHAEL
权利人:T C ERCIYES UENIVERSITESI
摘要:This invention relates to the synthesis of pyrimidine-4 (1H)-one derivatives from Meldrum's acid, carbonyl compounds (aldehyde/ketone), and guanylhydrazone derivatives and tautomers, enantiomers, and salts thereof.

专利号:US-2002042514-A1
优先权日:2000-06-26
标 题 :Synthesis of chlorinated pyrimidines
发明人：DOYLE TIMOTHY JOHN; WEHRENBERG PETER KARL; STANDEN MICHAEL CHARLES HENRY
摘要:A facile process for the preparation of 4,6-dichloropyrimidine is provided, which utilizes quaternary ammonium salts or quaternary phosphonium salts as catalysts for the reaction of, for example, 4,6-dihydroxypyrimidine or 4-chloro-6-methoxypyrimidine with phosgene.

专利号:WO-2025056767-A1
优先权日:2023-09-15
标题 :Process for the preparation of enantiomerically enriched aliphatic amines
发明人：BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
权利人:SYNGENTA CROP PROTECTION AG
摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

专利号:US-2016073631-A1
优先权日:2013-03-04
标 题 :Process for the preparation of dihydropyrrole derivatives
发明人：EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
权利人:SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) n n n n n n n n n n n n wherein n P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; n R 1 is chlorodifluoromethyl or trifluoromethyl; n R 2 is optionally substituted aryl or optionally substituted heteroaryl; n n is 0 or 1; n including the process comprising n (a-i) reacting a compound of formula II n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; n with nitromethane in the presence a chiral catalyst to give a compound of formula III n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; and n (a-ii) reductively cyclising the compound of formula III to give the compound of formula I. n n n n n The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

专利号:US-9233920-B2
优先权日:2010-06-11
标题 :Process for the preparation of dihydropyrrole derivatives
发明人：EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
权利人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS; SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) wherein P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; R 1 is chlorodifluoromethyl or trifluoromethyl; R 2 is optionally substituted aryl or optionally substituted heteroaryl; n is 0 or 1; including the process comprising (a-i) reacting a compound of formula II wherein P, R 1 and R 2 are as defined for the compound of formula I; with nitromethane in the presence a chiral catalyst to give a compound of formula III Wherein P, R 1 and R 2 are as defined for the compound of formula I; and (a-ii) reductively cyclizing the compound of formula III to give the compound of formula I. The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

专利号:US-6608199-B2
优先权日:2000-07-07
标题 :Synthesis of chlorinated pyrimidines
发明人：DOYLE TIMOTHY JOHN; BENKE ALAN HENRY; WEHRENBERG PETER KARL; NADY LOUIE AKOS
权利人:SYNGENTA LTD
摘要:The invention provides a process for synthesizing chlorinated pyrimidines. The process includes reacting imidoyl chloride compounds with phosgene (COCl2). The imidoyl chloride compounds can be supplied as starting materials or can be produced by reacting organic amides with phosgene or reacting organic nitrites with hydrogen chloride. The chlorinated pyrimidines, such as 4,6-dichloropyrimidine, can be used to synthesize other compounds useful in a variety of compositions, such as fungicides, pesticides, and pharmaceuticals.