CAS: 505-79-3; 3-(Methylthio)Propylisothiocyanate

上下游产品

thiophosgene 3-methylthio-1-propanamine 3-(methylthio)propyl thi°Cyanate iberin

3-(Methylthio)Propyl Thiocyanate置于四丁基溴化铵,N,N-二甲基甲酰胺体系中,用 水 作为反应溶剂,化学反应 1.0H,以32.9 G的收率获得产物3-(甲硫基)丙基异硫氰酸酯
参考文献:Structure-activity Relationship Study On Isothiocyanates: Comparison Of Trpa1-Activating Ability Between Allyl Isothiocyanate And Specific Flavor Components Of Wasabi,Horseradish,And White Mustard
标题:Structure-activity Relationship Study On Isothiocyanates: Comparison Of Trpa1-Activating Ability Between Allyl Isothiocyanate And Specific Flavor Components Of Wasabi,Horseradish,And White Mustard
摘要:Allyl Isothiocyanate (Itc) (4) Is The Main Pungent Component In Wasabi,And It Generates An Acrid Sensation By Activating Trpal The Flavor And Pungency Of Itcs Vary Depending On The Compound. However,The Differences In Activity To Activate Trpa1 Between Itcs Are Effect Of Carbon Chain Length And Substituents Of Itcs,The Not Known Except For A Few Compounds. To Investigate The Trpa1-Activiting Ability Itcs Was Measured. Since Most Of The Itcs Showed Nearly Equal Trpa1-Activiting Potency,. The Itc Moiety Is Likely The Predominant Contributor To Their Trpa1-Activating Abilities,And Contributions Of Other Functional Groups To Their Activities To Activate Trpa1 Are Comparatively Small.
DOI:10.1021/acs.Jnatprod.5B00272

专利信息

专利号:WO-2025069039-A1
优先权日:2023-09-28
标题:An in situ process for the preparation of primary amine compounds
发明人：SAMANT RAJARAM; TONGRA MANOJ
权利人:SAMANT RAJARAM; TONGRA MANOJ
摘要:An in situ process for the preparation of primary amine compounds The invention disclosed herein relates to an in situ process for the preparation of primary amine compounds. Particularly, it relates to the preparation of primary amine compounds having general Formula (I). Formula (I) wherein n is 1 to 9 and X is -S, -N- or -O. More particularly, the present invention relates to the preparation of primary amine compounds with high yield and purity which is further used as potent intermediate in the synthesis of therapeutically active isothiocyanates (ITCs).

专利号:WO-0166611-A1
优先权日:2000-03-07
标题 :Method for carrying out the rare earth metal-catalyzed synthesis of polyacrylates having a high isotacticity
发明人：ANWANDER REINER; GOERLITZER HANS W; HERRMANN WOLFGANG A; DORN KLAUS; OSTHAUS ELKE; SCHWIND HELMUT
权利人:ROEHM GMBH; ANWANDER REINER; GOERLITZER HANS W; HERRMANN WOLFGANG A; DORN KLAUS; OSTHAUS ELKE; SCHWIND HELMUT
摘要:The invention relates to a method for producing polymerizates and copolymerizates of alpha -substituted acrylic compounds according to which one or more polymerizable monomeric compounds of general formula (I), wherein R<1> and R<2> assume the meanings as cited in the description, is/are polymerized, in the presence of a catalytically active structure, obtained in situ from an organometallic rare earth metal (III) complex or from a rare earth metal (II) complex of general formula (II): [(IND)A(IND)]LnR<6>, wherein: IND signifies a substituted indenyl group or a substituted cyclopentadienyl group with a fused aromatic or aliphatic ring; A represents a diyl radical which bridges two IND units and which comprises an element from groups 13, 14, 15 or 16 of the periodic table; Ln represents a rare earth metal in oxidation step +3 or +2, and; R<6> represents a hydride ligand or a ligand that is capable of forming agostic interactions, or represents a neutral donor ligand (e.g. tetrahydrofuran). The one or more polymerizable monomeric compounds is/are polymerized in an aprotic solvent for the catalytically active compound at temperatures ranging from -100 DEG C to the boiling point of the solvent. The polymerizate or copolymerizate obtained from the polymerization is, in an appropriate manner, isolated or subjected to an additional processing in solution. The invention also relates to the obtained polymerizates and copolymerizates which have a high isotacticity.

专利号:DE-202025100799-U1
优先权日:2025-02-17
标题 :System for the synthesis of N-(3-(Methylthio)propyl)-thiosemicarbazide-derived imine derivatives for the treatment of diabetics

专利号:RU-2205220-C2
优先权日:1996-02-29
标 题:METHOD OF SYNTHESIS OF α-HYDROXYACIDS USING NOVEL MICROORGANISM AND NOVEL MICROORGANISM

专利号:US-7358362-B2
优先权日:2004-01-23
标题:Method for the production of terylene-3,4:11,12-tetracarboxydiimides by direct synthesis
发明人：KOENEMANN MARTIN; BOEHM ARNO; HELFER WILLI; ROMEIS JUERGEN; QU JIANQIANG; MUELLEN KLAUS
权利人:BASF AG; MAX PLANCK GESELLSCHAFT
摘要:A process for preparing terylene-3,4:11,12-tetracarboximides I n nwhere the variables are each defined as follows:n R, R′ are each independently hydrogen; if desired substituted alkyl or cycloalkyl; R 1 is hydrogen or alkyl; R 2 is hydrogen; alkyl; if desired substituted aryl or hetaryl,n nby reacting a perylene-3,4-dicarboximide IIn n nin the presence of a base-stable, high-boiling organic solvent and of an alkali metal or alkaline earth metal base, with a naphthalene-1,8-dicarboximide IIIn n nin which X is hydrogen, bromine or chlorine.

专利号:US-3146227-A
优先权日:1962-09-27
标 题:Synthesis of mustard oil glucosides
发明人：ETTLINGER MARTIN G; DATEO JR GEORGE P
权利人:ETTLINGER MARTIN G; DATEO JR GEORGE P