CAS: 51372-93-1; (S)-Tert-Butyl (1-Hydroxy-4-(Methylthio)Butan-2-yl)Carbamate

相似化合物

2899-37-8 2488-15-5 5241-66-7

上下游产品

CAS号2488-15-5 B°C-L-蛋氨酸 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号2899-37-8 L-(-)-蛋氨醇 | CAS号76220-80-9 B°C-Met-OEt | CAS号33900-24-2 N-tert-butoxyca... | CAS号63-68-3 L-蛋氨酸 | CAS号27067-02-3 N-B°C-(S)-methi... | CAS号34619-03-9 碳酸二叔丁酯 | CAS号10332-17-9 L-Methionine, m... | CAS号95715-87-0 (R)-(+)-3-B°C-2... | CAS号486460-00-8 (3R)-N-叔丁氧羰基-3-... | CAS号133625-87-3 (S)-2,2-二甲基-4-乙... | CAS号91103-37-6 (S)-(1-羟基丁-3-烯-...

Boc-L-蛋氨酸置于n-甲基吗啉,甲醇,Sodium Tetrahydroborate体系中,用 四氢呋喃 作为反应溶剂,化学反应 0.33H,反应生成 N-叔丁氧羰基-L-蛋氨醇
参考文献:A Convenient One-Pot Conversion Ofn-Protected Amino Acids And Peptides Into Alcohols
标题:A Convenient One-Pot Conversion Ofn-Protected Amino Acids And Peptides Into Alcohols
摘要:N-保护氨基酸和肽通过其相应的混合酸酐的选择性还原,使用逐滴加入甲醇的条件下,在四氢呋喃中与硼氢化钠反应,被转化为醇.
DOI:10.1055/s-1990-26857

专利信息

专利号:US-2021171437-A1
优先权日:2017-07-17
标题 :Peptide nucleic acid (pna) monomers with an orthogonally protected ester moiety and novel intermediates and methods related thereto
发明人：COULL JAMES M; GILDEA BRIAN D
权利人:VERA THERAPEUTICS INC
摘要:The present disclosure pertains to peptide nucleic acid (PNA) monomers and oligomers, as well as methods and compositions useful for the preparation of PNA monomer precursors (e.g. PNA Monomer Esters, Backbone Esters and Backbone Ester Acid Salts, as described below) that can be used to prepare PNA monomers wherein said PNA monomers can be used to prepare said PNA oligomers. In some embodiments, the disclosure features sulfonic acid salts of Backbone Ester compounds, which sulfonic acid salts generally tend to be crystalline and can be obtained in reasonably good yield, often without requiring any chromatographic purification of the reaction product of the Backbone Ester synthesis reaction. This disclosure also pertains to novel methods for the synthesis of said Backbone Ester compounds and novel methods for the formation of the related sulfonic acid salts. Exemplary ester groups include, but are not limited to, 2,2,2-trichloroethy-(TCE), 2,2,2-tribromoethyl-(TBE), 2-iodoethyl-groups (2-IE) and 2-bromoethyl-(2-BrE) as the ester group. These particular ester groups can be removed under conditions where both Boc and Fmoc protected amine groups are stable.

专利号:US-9695119-B2
优先权日:2008-08-01
标题:Methionine analogs and methods of using same
发明人：BASSIRI MANSOUR; RAHIMI-LARIJANI AFSANEH
权利人:BIOXINESS PHARMACEUTICALS INC
摘要:Provided are methionine analogs which may be useful for inhibiting protein synthesis, inhibiting microbial growth and/or treating infectious diseases. In some instances, the analogs exhibit bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and/or antiviral properties. Also provided are methods of treatment and methods of preparation, as well as kits and unit dosages.