3-羟基-2-硝基吡啶置于甲醇,五氯化磷,水,硝酸,Silver(I) Acetate,乙酸酐,肼体系中,化学反应 2.0H,反应生成 2-硝基-5-氯吡啶 参考文献:Czuba; Plazek,Recueil Des Travaux Chimiques Des Pays-Bas,1958,Vol. 77,P. 92,95 标题:Czuba; Plazek,Recueil Des Travaux Chimiques Des Pays-Bas,1958,Vol. 77,P. 92,95
专利号:US-2016257688-A1 优先权日:2013-10-24 标 题 :Process for Synthesis of Lactams 发明人:TAVARES FRANCIS XAVIER 权利人:TAVARES FRANCIS XAVIER 摘要:Methods for the synthesis of lactams are presented whereby a carboxylic acid of the formula HOOC—OR—NH-LG, wherein OR is an organic moiety and LG is a leaving group, is reacted with an acid, such as an organic acid, in particular a strong acid, and a dehydrating agent, which may be one in the same such as a strong acid anhydride, such that the amount of acid added allows for the desired transformation to take place without the loss of the leaving group (LG) before the cyclization, and recovering the lactam such as that of the formula (a), provided herein, wherein G represents the atom(s) needed to form a closed ring.
专利号:US-2015087831-A1 优先权日:2012-04-26 标题:Synthesis of lactams
专利号:US-3963734-A 优先权日:1971-09-17 标 题:Lower alkylsulfonyl 2-amino, 3-nitro pyridines 发明人:DOHERTY GEORGE O P; FUHR KENNETH H 权利人:LILLY CO ELI 摘要:Substituted 1-hydroxy-2-(1,1-difluoroalkyl)-1H-imidazo-(4,5-b)pyridine compounds useful as herbicides; and intermediates useful in the synthesis of these compounds. In addition to exhibiting herbicidal activity, the substituted 1-hydroxy-2-(1,1-difluoroalkyl)-1H-imidazo(4,5-b)pyridine compounds are of low mammalian toxicity.
专利号:US-4087432-A 优先权日:1974-05-23 标 题 :1H-imidazo(4,5-b)pyridine compounds 发明人:O DOHERTY GEORGE O P; FUHR KENNETH H 权利人:LILLY CO ELI 摘要:Substituted 1-hydroxy-2-(1,1-difluoroalkyl)-1H-imidazo-(4,5-b)pyridine compounds useful as herbicides; and intermediates useful in the synthesis of these compounds. In addition to exhibiting herbicidal activity, the substituted 1-hydroxy-2-(1,1-difluoroalkyl)-1H-imidazo(4,5-b)pyridine compounds are of low mammalian toxicity.
专利号:US-3968116-A 优先权日:1971-09-17 标 题 :1H-imidazo(4,5-b)pyridine compounds 发明人:DOHERTY GEORGE O P; FUHR KENNETH H 权利人:LILLY CO ELI 摘要:Substituted 1-hydroxy-2-(1,1-difluoroalkyl)-1H-imidazo-(4,5-b)pyridine compounds useful as herbicides; and intermediates useful in the synthesis of these compounds. In addition to exhibiting herbicidal activity, the substituted 1-hydroxy-2-(1,1-difluoroalkyl-1H-imidazo(4,5-b)pyridine compounds are of low mammalian toxicity.
专利号:WO-2015061407-A1 优先权日:2013-10-24 标题 :Process for synthesis of lactams