CAS: 772-49-6; 1-Chloro-3-(Trifluoromethoxy)Benzene

上下游产品

CAS号373-91-1 三氟甲基次氟酸酯 | CAS号108-90-7 氯苯 | CAS号456-55-3 三氟甲氧基苯

苯甲酰溴置于二环己烷并-18-冠醚-6,Potassium Fluoride,1-溴全氟乙烷,四丁基二氟三苯硅酸铵体系中,用 乙酸乙酯 作为反应溶剂,化学反应 14.5H,反应生成 间氯三氟甲氧基苯
参考文献:三氟甲基苯甲酸酯 (Tfbz):多功能三氟甲氧基化试剂
标题:三氟甲基苯甲酸酯 (Tfbz):多功能三氟甲氧基化试剂
摘要:苯甲酸三氟甲酯 (Tfbz) 被开发为一种新的货架稳定的三氟甲氧基化试剂,它可以很容易地从廉价的原料中制备,使用 Kf 作为唯一的氟源.芳烃的三氟甲氧基化-卤化,烷基(伪)卤化物的亲核取代,与芳基锡烷的交叉偶联和烯烃的不对称双官能化证明了 Tfbz 的合成效力.在冠醚络合的钾阳离子的帮助下,芳炔的前所未有的三氟甲氧基化-卤化在室温下顺利进行,这显着稳定了衍生自 Tfbz 的三氟甲氧基阴离子.
DOI:10.1021/jacs.8B04000

专利信息

专利号:US-2013184465-A1
优先权日:2010-09-30
标 题:Process for the synthesis of thio-triazolo-group containing compounds
发明人：DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL
权利人:DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL; BASF SE
摘要:The present invention relates to a process using specific magnesium reagents for providing thio-triazolo group-containing compounds and for the synthesis of precursors therefor. The invention furthermore relates to intermediates and to their preparation.

专利号:US-4157344-A
优先权日:1978-01-16
标题 :Preparation of aryl trifluoromethyl ethers
发明人：FEIRING ANDREW E
权利人:DU PONT
摘要:A one-step process for the synthesis of aryl trifluoromethyl ethers by reacting phenol or certain substituted phenols with a perhalomethane and hydrogen fluoride is provided. The compounds produced by the process of this invention are useful intermediates in the production of dyestuffs and pharmaceuticals.

专利号:US-4446078-A
优先权日:1982-01-21
标 题 :Process for the preparation of α,α-difluoroalkyl-thiophenyl ketones
发明人：DESBOIS MICHEL
权利人:RHONE POULENC SPEC CHIM
摘要:A process for the preparation of alpha , alpha -difluoroalkoxy or alpha , alpha -difluoroalkylthiophenyl ketones, in which a polyhaloalkoxybenzene or a polyhaloalkylthiobenzene is reacted with a carboxylic acid, a precursor or a derivative of this acid in the presence of boron trifluoride in such an amount that the absolute pressure of the boron trifluoride within the reaction vessel exceeds 1 bar, and in the presence of hydrofluoric acid as a solvent. The resultant products are useful as intermediates in the synthesis of compounds having phytosanitary (e.g., herbicidal) or pharmaceutical activity.

专利号:US-4438043-A
优先权日:1982-04-22
标题:Process for preparation of di- or trifluoromethoxyphenyl ketones or di- or trifluoromethylthiophenyl ketones
发明人：DESBOIS MICHEL
权利人:RHONE POULENC SPEC CHIM
摘要:A process for the preparation of di- or trifluoromethoxyphenyl ketones or di- or trifluoromethylthiophenyl ketones, characterized in that, in a first stage, a di- or trihalomethoxybenzene or a di- or trihalomethylthiobenzene is reacted with a trihalomethylated aromatic or aliphatic compound in the presence of boron trifluoride in an amount such that the absolute pressure of boron trifluoride within the reaction vessel exceeds 1 bar, and in the presence of hydrofluoric acid as a solvent and in that, in a second stage, the product of the first stage is hydrolyzed. The resultant products are useful as intermediates in the synthesis of compounds having a pharmaceutical or phytosanitary (e.g., herbicidal) activity.

专利号:EP-1930323-A1
优先权日:2004-03-11
标 题:Biphenyl compounds useful in the synthesis of muscarinic receptor antagonists

专利号:WO-2012041858-A1
优先权日:2010-09-30
标 题:A process for the synthesis of thio-triazolo-group containing compounds