CAS: 205524-46-5; (R)-Tert-Butyl 5-Oxopyrrolidine-2-Carboxylate

主要参考文献

参考标题:Synthesis Of α‐ketoamide‐based Stereoselective Calpain‐1 Inhibitors As Neuroprotective Agents
作者:Ammar Jastaniah,Irina N. Gaisina,Rachel C. Knopp,Gregory R. J. Thatcher |发布日期:2020.12.3
摘要:Potentially Including Abt‐957 Was Optimized To Yield Diastereomerically Pure Compounds That Are Potent And Selective For Calpain‐1 Over Papain And Cathepsins B And K. As The Final Oxidation Step, With Its Optimized Synthesis Protocol, Does Not Alter The Configuration Of The Substrate, The Synthesis Of The Diastereomeric Pair (R)‐1‐benzyl‐n‐((S)‐4‐((4‐fluorobenzyl)Amino)‐3,4‐dioxo‐1‐phenylbutan‐2‐yl)‐5‐oxopy

合成参考文献

参考文献:10.1007/s007830050060
摘要:Ciapetti P, Falorni M, Mann A, Taddei M. 2-Amino-4-bromobutanoic Acid. Molecules Online. 1998 Apr;2(2):86–93. doi: 10.1007/s007830050060.