CAS: 21850-12-4; Octahydro-1H-Isoindole

该化合物是一个双环有机化合物,其独特结构由饱和异硫醇框架组成,其独特结构具有两环性质,该化合物具有一个包括六人和五人环的引信环系统,其化学特性不同,通常无色可粉黄黄色液体或固体,因其特定形式和纯度而不同;该化合物因其在有机合成中的潜在应用以及作为各种药品和农用化学品生产的中间体而著称;其再活动受氮在环状结构中的存在的影响,氮可以参与各种化学反应,包括核生殖器替代和环状添加剂;此外,Cis-Octahyoindole可能表现出有趣的物理特性,例如有机溶剂中的溶液和中度挥发性;在处理和储存时,应参考安全数据,如任何化学物质,以确保采取适当的防范措施.

结构式图片

相似化合物

1470-99-1 161829-92-1 6949-87-7

欧盟法规

ECHA物质C&L通报

合成工艺路线路线简述

    六氢邻苯二甲酰亚胺置于lithium Aluminium Tetrahydride,水,Sodium Hydroxide体系中,用 四氢呋喃 用作溶剂,化学反应 20.0H,反应生成八氢-1H-异吲哚
    参考文献:New Tertiary 8-Hydroxyquinoline-7-Carboxamide Derivatives And Uses Thereof
    标题:New Tertiary 8-Hydroxyquinoline-7-Carboxamide Derivatives And Uses Thereof
    摘要:新的三级8-羟基喹啉-7-甲酰胺衍生物的一般化学式(i)及其药用盐已被披露. 这些化合物可用作抗真菌剂.具体来说,这些化合物已对白色念珠菌,白色念珠菌,黑曲霉和短柄曲霉进行了测试.这些化合物也对白色念珠菌属的物种如白色念珠菌和光滑白色念珠菌具有活性.

    海关参考信息

    专利信息


    专利号:US-4902817-A
    优先权日:1987-09-17
    标 题 :Process for the synthesis of alpha n alkylated amino acids and esters thereof, application to the synthesis of carboxyalkyl dipeptides
    发明人:VINCENT MICHEL; BALIARDA JEAN; MARCHAND BERNARD; REMOND GEORGES
    权利人:ADIR
    摘要:Stereoselective process for the industrial synthesis of compounds of formula (I): ##STR1## where R 1 is linear or branched lower alkyl with 1 to 6 carbon atoms, n R 2 is a linear or branched lower alkyl with 1 to 4 carbon atoms, n employing inexpensive starting materials and obtaining optimum yields. n Application to the synthesis of carboxyalkyl dipeptides.

    专利号:WO-2023102600-A1
    优先权日:2021-12-06
    标题:Synthesis of amphiphilic block copolymers and polymeric nanofibers produced therefrom
    发明人:ZETTERLUND PER B; ISHIZUKA FUMI; KIM HYUN JIN; CHATANI SHUNSUKE; NIINO HIROSHI
    权利人:NEWSOUTH INNOVATIONS PTY LTD
    摘要:The present disclosure relates to the field of synthesis of block copolymers, and polymeric nanofibers having a core-shell morphology produced therefrom. The present disclosure relates to the field of synthesis of block copolymers where one block is more hydrophobic than the other block and is a different composition. The disclosure also relates to uses of these polymeric nanofibers in various applications, such as reinforcing a polymeric matrix and for coatings applications.

    专利号:EP-0309324-B1
    优先权日:1987-09-17
    标 题:Process for the preparation of n-alkylated amino acids and their esters, use in the synthesis of carboxyalkyl dipeptides
    摘要:Process for industrial synthesis of the derivative of formula (I): and their addition salts with an inorganic or organic acid or base, in which: R1 is linear or branched lower alkyl (of 1 to 6 carbon atoms), R2 is hydrogen or a linear or branched lower alkyl group (of 1 to 4 carbon atoms). Application to the industrial synthesis of carboxyalkyl dipeptides.

    专利号:US-2006167025-A1
    优先权日:2004-12-22
    标 题:Tricyclic amino alcohols, processes for synthesis of same and use of same as anti-inflammatory drugs
    发明人:BERGER MARKUS; SCHMEES NORBERT; SCHAECKE HEIKE; BAURLE STEFAN; REHWINKEL HARTMUT; MENGEL ANNE; KROLIKIEWICZ KONRAD; GROSSBACH DANJA; VOIGTLAENDER DAVID
    权利人:BERGER MARKUS; SCHMEES NORBERT; SCHAECKE HEIKE; BAURLE STEFAN; REHWINKEL HARTMUT; MENGEL ANNE; KROLIKIEWICZ KONRAD; GROSSBACH DANJA; VOIGTLAENDER DAVID
    摘要:The invention relates to tricyclic amino alcohols of general formula (I) n nmethod for synthesis of same and use of same as anti-inflammatory agents.

    专利号:US-10918627-B2
    优先权日:2016-05-11
    标 题:Convergent and enantioselective total synthesis of Communesin analogs
    发明人:MOVASSAGHI MOHAMMAD; LATHROP STEPHEN PAUL; POMPEO MATTHEW W; CHANG WEN-TAU TIMOTHY
    权利人:MASSACHUSETTS INST TECHNOLOGY
    摘要:A highly convergent biomimetic synthesis of a complex polycyclic scaffold has been successfully implemented. From these efforts, compounds having a structure of Formula (I): n nor a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R 1 -R 8 and m, n, r, s, t, and u are as defined herein, is provided. Methods of making such compounds are also disclosed as are methods for the treatment of cancer, various infectious diseases, and abnormal cardiovascular function.

    专利号:US-2014275582-A1
    优先权日:2013-03-14
    标 题 :Chiral 2-arylpropyl-2-sulfinamide and chiral n-2-arylpropyl-2-sulfinylimines and synthesis thereof
    发明人:LI GUIGEN
    权利人:LI GUIGEN; UNIV TEXAS TECH; NANJING UNIVERSITY INST OF CHEMISTRY AND BIOMEDICAL SCIENCES
    摘要:Provided herein are novel chiral sulfinamide and imine compounds. Also provided herein are methods of synthesizing novel chiral sulfinamide and imine compounds comprising simplified purification methods when compared to prior methods. The novel chiral sulfinamide and imine compounds are useful, for example, in the synthesis of complex natural products and pharmaceutical important compounds.
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    合成参考文献


    参考文献:10.1007/978-3-031-18587-8_17
    摘要:Contigli C, Valle MS, Oloris SCS, Pimenta LPS, Takahashi JA. Polyketides from Fungi. 2023. In: Natural Secondary Metabolites.
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