CAS: 364-76-1; 4-Fluoro-3-Nitroaniline

上下游产品

2,4-Dinitrofluorobenzene 4-fluoroaniline sulfuric acid nitric acid 4-fluoro-3-nitro-phenyl isothi°Cyanate (E)-1-(2,4-dinitrophenyl)-2-(4-fluoro-3-nitrophenyl)diazene 4-diazo-2-nitrophenol 1-ethoxy-2-nitrobenzene

2,4-二硝基氟苯置于氢氧化钾,氢气体系中,用 异丙醇 作为反应溶剂,化学反应 3.0H,以79%的收率获得产物4-氟-3-硝基苯胺
参考文献:钴(II)取代的六角形介孔铝磷酸盐分子筛上芳族硝基和羰基化合物的非均相催化转移加氢
标题:钴(II)取代的六角形介孔铝磷酸盐分子筛上芳族硝基和羰基化合物的非均相催化转移加氢
摘要:芳香族硝基和羰基化合物的催化转移氢化反应是使用新型的钴(II)取代的六角形介孔铝磷酸盐分子筛进行的.该催化剂显示出优异的产率和非常好的再循环能力.
DOI:10.1016/s0040-4039(02)02080-4

专利信息

专利号:US-7897762-B2
优先权日:2006-09-14
标 题:Kinase inhibitors useful for the treatment of proliferative diseases
发明人：FLYNN DANIEL L; PETILLO PETER A; KAUFMAN MICHAEL D; PATT WILLIAM C
权利人:DECIPHERA PHARMACEUTICALS LLC
摘要:The present invention relates to novel kinase inhibitors and modulator compounds useful for the treatment of various diseases. More particularly, the invention is concerned with such compounds, kinase/compound adducts, methods of treating diseases, and methods of synthesis of the compounds. Preferably, the compounds are useful for the modulation of kinase activity of Raf kinases and disease polymorphs thereof. Compounds of the present invention find utility in the treatment of mammalian cancers and especially human cancers including but not limited to malignant melanoma, colorectal cancer, ovarian cancer, papillary thyroid carcinoma, non small cell lung cancer, and mesothelioma. Compounds of the present invention also find utility in the treatment of rheumatoid arthritis and retinopathies including diabetic retinal neuropathy and macular degeneration.

专利号:US-7151112-B1
优先权日:2001-09-04
标题:Pharmaceutical uses and synthesis of nicotinamides
发明人：CUTSHALL NEIL S; JEFFREY SCOTT C
权利人:UCB SA
摘要:This invention is directed to methods of using a compound of the formula n nand pharmaceutically acceptable salts thereof, wherein n, X, R 1 and R 2 are disclosed herein, for treating inflammatory events in an animal subject.

专利号:US-3798201-A
优先权日:1972-02-24
标 题 :Molten lewis acid high performance heterocyclic polymer polymerization
发明人：SAFERSTEIN L; MANNION W
权利人:CELANESE CORP
摘要:AN IMPROVED PROCESS IS PROVIDED FOR THE SYNTHESIS OF HIGH PERFORMANCE HETEROCYCLIC POLYMERS WHEREIN THE PRLYMERIZATION IS CONDUCTED IN THE PRESENCE OF A MOLTEN LEWIS ACID SELECTED FOR ITS ABILITY TO DISSOLVE THE HIGH MOLECULAR WEIGHT POLYMER AND TO REMOVE WATER PRODUCED VIA THE CONDENSATION REACTION.

专利号:US-5105012-A
优先权日:1989-03-24
标题 :Catalytic reduction of dinitrobenzenes using a noble metal catalyst and iron or iron salts
发明人：THEODORIDIS GEORGE
权利人:FMC CORP
摘要:There is provided an improved process for the reduction of optionally substituted dinitrobenzenes to the corresponding nitroanilines with high yields which comprises contacting the dinitrobenzene with hydrogen in an acidic medium in the presence of a catalytic amount of a combination of a noble metal hydrogenation catalyst, and iron or an iron salt. Isomer specific reductions may be achieved with those compounds containing suitable directing substituents. The 2-halo-5-nitroanilines which may be produced in this process may be converted via a multi-step synthesis to useful 1-aryl-4-substituted 1,4-dihydro-5H-tetrazol-5-one herbicides.

专利号:CN-108191681-A
优先权日:2018-01-12
标 题 :One-step Synthesis of 3-Nitro-4-Hydroxyethylamino-N,N-Dihydroxyethylaniline

专利号:US-6777432-B1
优先权日:2001-09-04
标 题 :Pharmaceutical uses and synthesis of nicotinamides