CAS: 5216-25-1; 1-Chloro-4-(Trichloromethyl)Benzene

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CAS号106-43-4 对氯甲苯 | CAS号13940-94-8 对氯苯基二氯甲烷 | CAS号98-59-9 对甲苯磺酰氯(PTSC) | CAS号98-07-7 三氯甲苯 | CAS号99-96-7 4-羟基苯甲酸 | CAS号7647-18-9 氯化锑(V) | CAS号7553-56-2 碘 | CAS号100-44-7 氯化苄 | CAS号455-86-7 3,4-二氟苯甲酸 | CAS号454-78-4 3-溴-4-氯三氟甲苯 | CAS号66682-07-3 3,4,5-trichloro... | CAS号2136-87-0 1,2,3,4-tetrach... | CAS号13014-24-9 3,4-二氯三氯苄 | CAS号27020-90-2 2,4,5-trichloro... | CAS号1871-38-1 4-氯苯甲酸苯酯 | CAS号90-98-2 4,4'-二氯二苯甲酮 | CAS号2491-90-9 2,5-双(4-氯苯基)-1,... | CAS号98-56-6 4-氯三氟甲苯

对氯苯基二氯甲烷置于一氧化二氯体系中,用 四氯化碳 作为反应溶剂,化学反应生成 4-氯三氯甲苯
参考文献:一氧化二氯:一种强大的选择性氯化试剂
标题:一氧化二氯:一种强大的选择性氯化试剂
摘要:-一氧化二氯是一种强大的选择性试剂,可用于失活芳族底物的侧链或环氯化.它在常规试剂失效或需要苛刻条件的温和条件下提供出色的产品收率.已经使用线性自由能关系,同位素效应和竞争动力学研究探索了一氧化二氯反应的机理方面.
DOI:10.1021/ja00381A032

专利信息

专利号:US-4453012-A
优先权日:1982-04-22
标 题 :Process for the preparation of phenyl ketones
发明人：DESBOIS MICHEL
权利人:RHONE POULENC SPEC CHIM
摘要:A process for the preparation of phenyl ketones, characterized in that, in a first stage, a halo- or trihalomethylbenzene is reacted with a trihalomethylated aliphatic or aromatic compound in the presence of boron trifluoride in an amount such that the absolute pressure of boron trifluoride within the reaction vessel exceeds 1 bar, and in the presence of hydrofluoric acid as a solvent, and in that, in a second stage, the resultant product is hydrolyzed. The products are used as intermediates in the synthesis of compounds having a pharmaceutical or phytosanitary (e.g., herbicidal) activity.

专利号:US-4876376-A
优先权日:1983-06-23
标题 :Process for the halogenation, nitration and fluorination of aromatic derivatives
发明人：DESBOIS MICHAEL; DISDIER CAMILLE
权利人:RHONE POULENC SPEC CHIM
摘要:A process for the halogenation (bromination or chlorination)/nitration/fluorination of aromatic derivatives substituted by at least one group containing a halogenoalkyl unit. The aromatic derivative is reacted with a halogen and a nitrating agent in liquid hydrofluoric acid. The products obtained are useful as intermediates for the synthesis of compounds having a plant-protecting or pharmaceutical activity.

专利号:US-4438043-A
优先权日:1982-04-22
标题:Process for preparation of di- or trifluoromethoxyphenyl ketones or di- or trifluoromethylthiophenyl ketones
发明人：DESBOIS MICHEL
权利人:RHONE POULENC SPEC CHIM
摘要:A process for the preparation of di- or trifluoromethoxyphenyl ketones or di- or trifluoromethylthiophenyl ketones, characterized in that, in a first stage, a di- or trihalomethoxybenzene or a di- or trihalomethylthiobenzene is reacted with a trihalomethylated aromatic or aliphatic compound in the presence of boron trifluoride in an amount such that the absolute pressure of boron trifluoride within the reaction vessel exceeds 1 bar, and in the presence of hydrofluoric acid as a solvent and in that, in a second stage, the product of the first stage is hydrolyzed. The resultant products are useful as intermediates in the synthesis of compounds having a pharmaceutical or phytosanitary (e.g., herbicidal) activity.

专利号:US-4575571-A
优先权日:1983-06-23
标题:Process for the simultaneous halogenation and fluorination of aromatic derivatives
发明人：DESBOIS MICHEL; DISDIER CAMILLE
权利人:RHONE POULENC SPEC CHIM
摘要:A process for the stimulaneous halogenation and fluorination of aromatic derivatives substituted by at least one group containing a halogenoalkyl unit. The aromatic derivative is reacted with the halogen in liquid hydrofluoric acid. The products obtained are useful as intermediates for the synthesis of compounds having a plant-protecting or pharmaceutical activity.

专利号:DE-4424036-A1
优先权日:1994-07-11
标题 :Process for the synthesis of polyaryl ether ketones using chlorohydroxyaromatics as a monomer component

专利号:CN-107151200-B
优先权日:2017-06-07
标 题:A continuous synthesis method of aromatic fluorine-containing compounds and its synthesis equipment