CAS: 6224-63-1; Tri-M-Tolylphosphine

上下游产品

CAS号28987-79-3 间甲苯基溴化镁 | CAS号6151-88-8 tri(3-methylphe... | CAS号373623-33-7 bromozinc(1+),m... | CAS号591-17-3 3-溴甲苯 | CAS号119821-88-4 (2-quinaldinate... | CAS号108-41-8 间氯甲苯

对氟甲苯置于六甲基磷酰三胺,Potassium Hydroxide Monohydrate,磷化氢体系中,化学反应 1.0H,以55%的收率获得产物三(间甲苯基)膦
参考文献:从芳基卤化物和红色磷中超碱辅助选择性合成三芳基膦:一锅中三个连续的不同snar反应
标题:从芳基卤化物和红色磷中超碱辅助选择性合成三芳基膦:一锅中三个连续的不同snar反应
摘要:红磷在超强碱体系中与芳基卤化物快速放热反应,以高收率得到三芳基膦.在一个锅中,通过s N Ar机制形成了三个连续的c(sp2)-P键.已经开发了这种环保,无pcl 3的可用原料合成ar 3 P的方法.
DOI:10.1002/ejoc.201901005

专利信息

专利号:US-10889599-B2
优先权日:2018-02-27
标 题:1,1-diborylalkyl-1-metal compounds, preparation method thereof, and their applications toward synthesis of 1,1-diboronate ester compounds
发明人：CHO SEUNG HWAN; LEE YEOSAN
权利人:POSTECH ACAD IND FOUND
摘要:The present invention relates to a 1,1-diborylalkyl-1-metal compound including one metal group together with two identical boron groups at the sp3 carbon center, and its use. Specifically, the present invention relates to development of novel organic reactions, synthesis of functional molecules, and synthesis of new drugs by applying the novel 1,1-diboryl-1-metal substituted alkyl compounds to various molecular libraries which could not be synthesized by conventional methodologies.

专利号:US-11560357-B2
优先权日:2018-09-22
标题 :Methods of producing pyrazole compounds
发明人：GUPTA RAMESH CHANDRA; SINGARAVEL MOHAN; CHHIPA LAXMIKANT; KASUNDRA ASHOK
权利人:TORRENT PHARMACEUTICALS LTD
摘要:The present invention is directed to methods of producing substituted pyrazole based compounds through novel intermediates and unique processes for preparing such intermediates which enables synthesis of final product through commercially viable route of synthesis. The present invention is also directed to novel methods of producing substituted pyrazole based thyroid like compounds, and solid forms of 3-{4-[(7-hydroxy-6-methyl-indan-4-yl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-propanoic acid, its pharmaceutical compositions, and methods of preparation thereof.

专利号:US-9273410-B2
优先权日:2009-01-16
标 题 :Low-temperature synthesis of colloidal nanocrystals
发明人：BARTL MICHAEL H; SIY JACQUELINE T
权利人:BARTL MICHAEL H; SIY JACQUELINE T; UNIV UTAH RES FOUND
摘要:Low-temperature organometallic nucleation and crystallization-based synthesis methods for the fabrication of semiconductor and metal colloidal nanocrystals with narrow size distributions and tunable, size- and shape-dependent electronic and optical properties. Methods include (1) forming a reaction mixture in a reaction vessel under an inert atmosphere that includes at least one solvent, a cationic precursor, an anionic precursor, and at least a first surface stabilizing ligand while stirring at a temperature in a range from about 50° C. to about 130° C. and (2) growing nanocrystals in the reaction mixture for a period of time while maintaining the temperature, the stirring, and the inert-gas atmosphere.

专利号:US-2009131660-A1
优先权日:2006-04-03
标 题 :SYNTHESIS OF 3-[4-(1,1-DIMETHYL-PROPYL)-PHENYL]-2-METHYL-PROPIONALDEHYDE AND cis-4--2,6-DIMETHYL-MORPHOLINE (AMOROLFINE)
发明人：BOITEAU JEAN-GUY; MUSICKI BRANISLAV
权利人:GALDERMA SA
摘要:3-[4-(1,1-Dimethyl-propyl)-phenyl]-2-methyl-propionaldehyde and cis-4-{3-[4-(1,1-dimethyl-propyl)-phenyl]-2-methyl-propyl}-2,6-dimethyl-morpholine (Amorolfine) are synthesized, first by Heck reacting a compound of general formula (VI): n n n n n n n n n n with 2-methyl-prop-2-en-1-ol of formula (VII): n n n n n n n n n n in the presence of a palladium catalyst and a base, in a solvent selected from among N,N-dimethylformamide, polar protic and non-polar organic solvents, and at a temperature ranging from 60° C. to 150° C., and then conducting an amino reduction by reacting the 3-[4-(1,1-dimethyl-propyl)-phenyl]-2-methyl-propionaldehyde of formula (II) with cis-2,6-dimethyl morpholine of formula (IV): n n n n n n n n n n in the presence of a reducing agent and in a solvent.

专利号:US-7030281-B2
优先权日:2002-03-21
标题 :Synthesis of 3,3,-dimethylbutyraldehyde by the reduction of 3,3,-dimethylbutyric acid
发明人：PRAKASH INDRA; AUGUSTINE ROBERT L; TANIELYAN SETRAK K
权利人:NUTRASWEET CO
摘要:A process for the production of 3,3-dimethylbutyraldehyde is disclosed. The 3,3-dimethylbutyraldehyde is obtained by the reduction of 3,3-dimethylbutyric acid using trimethylacetic anhydride and a phosphine. The 3,3-dimethylbutyric acid is preferably obtained by a process in which tert-butanol and vinylidene chloride are reacted in the presence of sulfuric acid. The disclosed process has improved cost and yield.

专利号:US-8178585-B2
优先权日:2007-11-14
标题 :Solvent-free synthesis of soluble nanocrystals
发明人：PETRUSKA MELISSA; PAN GUIQUAN
权利人:PETRUSKA MELISSA; PAN GUIQUAN; ADVANCED TECH MATERIALS
摘要:Methods for preparing high quality and high yields of nanocrystals, i.e., metal-oxide-based nanocrystals, using a novel solvent-free method. The nanocrystals advantageously comprise organic alkyl chain capping groups and are stable in air and in nonpolar solvents.