CAS: 6972-27-6; 6-Chloro-1,3-Dimethylpyrimidine-2,4(1H,3H)-Dione

相似化合物

31737-09-4 4318-56-3 6972-27-6

上下游产品

CAS号769-42-6 1,3-二甲基巴比妥酸 | CAS号4270-27-3 6-氯尿嘧啶 | CAS号74-83-9 溴甲烷 | CAS号4318-56-3 6-氯-3-甲基尿嘧啶 | CAS号89-25-8 依达拉奉 | CAS号35824-85-2 6-氯-5-甲酰基-1,3-二甲基尿嘧啶 | CAS号6642-31-5 1,3-二甲基-6-氨基脲嘧啶 | CAS号6320-15-6 2,4-二甲氧基-6-氯嘧啶 | CAS号74-88-4 碘甲烷 | CAS号104509-81-1 (6CI)-5-乙酰氨基-1,... | CAS号34654-81-4 6-(3-氯丙基)氨基1,3-... | CAS号5770-44-5 1,3-二甲基-6-(2-羟乙... | CAS号5440-00-6 5,6-二氨基-1,3-二甲基尿苷 | CAS号93787-99-6 1,3-二甲基-6-乙氧基尿嘧啶 | CAS号21428-25-1 2,4(1H,3H)-Pyri... | CAS号874-14-6 1,3-二甲基尿嘧啶 | CAS号2962-89-2 Benzo[g]pteridi... | CAS号769-42-6 1,3-二甲基巴比妥酸 | CAS号519-32-4 1,3,9-三甲基黄嘌呤

1,3-二甲基-6-氨基脲嘧啶置于硫酸,三氯氧磷体系中,用 水,甲苯 作为反应溶剂,化学反应 5.0H,反应生成 6-氯-1,3-二甲基脲嘧啶
参考文献:Cn116874435
标题:Cn116874435

专利信息

专利号:WO-2011114184-A1
优先权日:2010-03-15
标题 :Amides of heterocyclic compounds as trpa1 inhibitors
发明人：CHAUDHARI SACHIN SUNDARLAL; KUMAR SUKEERTHI; THOMAS ABRAHAM; PATIL NISHA PARAG; KADAM ASHOK BHAUSAHEB; WAGHMARE NAYAN TATERAO; KHAIRATKAR-JOSHI NEELIMA; MUKHOPADHYAY INDRANIL
权利人:GLENMARK PHARMACEUTICALS SA; CHAUDHARI SACHIN SUNDARLAL; KUMAR SUKEERTHI; THOMAS ABRAHAM; PATIL NISHA PARAG; KADAM ASHOK BHAUSAHEB; WAGHMARE NAYAN TATERAO; KHAIRATKAR-JOSHI NEELIMA; MUKHOPADHYAY INDRANIL
摘要:Amides of heterocyclic compounds as Transient Receptor Potential subfamily A (TRPA) modulators are provided In particular, compounds described herein are useful for treating or preventing diseases, conditions and/ or disorders modulated by TRPA1 (Transient Receptor Potential subfamily A, member 1) Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPA1. (I).

专利号:US-6180791-B1
优先权日:1989-03-23
标 题 :Synthesis of 8-substituted xanthines

专利号:US-8623880-B2
优先权日:2009-03-23
标 题 :Fused pyrimidine-dione derivatives as TRPA1 modulators
发明人：CHAUDHARI SACHIN SUNDARLAL; KUMAR SUKEERTHI; THOMAS ABRAHAM; PATIL NISHA PARAG; KADAM ASHOK BHAUSAHEB; DESHMUKH VISHAL GOVINDRAO; DHONE SACHIN VASANTRAO; CHIKHALE RAJENDRA PRAKASH; KHAIRATKAR-JOSHI NEELIMA; MUKHOPADHYAY INDRANIL
权利人:CHAUDHARI SACHIN SUNDARLAL; KUMAR SUKEERTHI; THOMAS ABRAHAM; PATIL NISHA PARAG; KADAM ASHOK BHAUSAHEB; DESHMUKH VISHAL GOVINDRAO; DHONE SACHIN VASANTRAO; CHIKHALE RAJENDRA PRAKASH; KHAIRATKAR-JOSHI NEELIMA; MUKHOPADHYAY INDRANIL; GLENMARK PHARMACEUTICALS SA
摘要:The invention described herein relates to novel fused pyrimidinediones derivatives of formula (I) which are TRPA (Transient Receptor Potential subfamily A) modulators. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPA1 (Transient Receptor Potential subfamily A, member 1). This invention also provides processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPA1.

专利号:US-9000159-B2
优先权日:2009-03-23
标 题 :Fused pyrimidine-dione derivatives as TRPA1 modulators
发明人：CHAUDHARI SACHIN SUNDARLAL; KUMAR SUKEERTHI; THOMAS ABRAHAM; PATIL NISHA PARAG; KADAM ASHOK BHAUSAHEB; DESHMUKH VISHAL GOVINDRAO; DHONE SACHIN VASANTRAO; CHIKHALE RAJENDRA PRAKASH; KHAIRATKAR-JOSHI NEELIMA; MUKHOPADHYAY INDRANIL
权利人:GLENMARK PHARMACEUTICALS SA; GLENMARK PHARMACEUTICALS SA
摘要:The invention described herein relates to novel fused pyrimidinediones derivatives of formula (I) which are TRPA (Transient Receptor Potential subfamily A) modulators. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPA1 (Transient Receptor Potential subfamily A, member 1). This invention also provides processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPA1.