合成目标产物 Aluminum Chloride 主要起始原料 Chlorine And Aluminum
(文献来源)合成步骤主要原料 Chlorine 和 Aluminum
氯置于clay,一氧化碳体系中,化学反应生成 三氯化铝 参考文献:Video Display System 标题:Video Display System 摘要:该发明使用多光束阴极射线管(6)来书写具有最大数据速率和写入速度降低因子等于同时操作光束数量的电视类型光栅或帧.为了克服图像中的过度斜率(图4A),采用了分步偏转(图4B),使得大部分垂直偏转发生在特定水平扫描完成之后,并在连续扫描开始之前.通过使用光学传输滤光器(20)进一步增加扫描速度,该滤光器能够选择性地传输阴极射线管屏幕发出的分离颜色,其中滤光器的一部分(20A)可以设置为传输颜色序列中的下一个颜色,而滤光器的其余部分(20B)正在传输当前显示的颜色.
专利信息
专利号:WO-2024185734-A1 优先权日:2023-03-03 标 题:Polyphosphorylated nucleoside, phosphate-activated nucleotide used for synthesis of polyphosphorylated nucleoside and method for synthesis of same, and method for synthesis of polyphosphorylated nucleoside using phosphate-activated nucleotide 发明人:KATAOKA MASANORI; FUKUI CHIHARU; TSUJI YOHEI; FUJIMURA Kazuma 权利人:NATIAS INC 摘要:The present invention provides: a polyphosphorylated nucleoside which has a structure represented by formula (I) and can be efficiently produced by a short process and a simple operation with use of a less expensive material; a phosphate-activated nucleotide which is used for the synthesis of the polyphosphorylated nucleoside and a method for the synthesis of this phosphate-activated nucleotide; and a method for the synthesis of a polyphosphorylated nucleoside using a phosphate-activated nucleotide. In the formula, B represents a protected or unprotected, natural or artificial nucleoside base; R 1 , R 2 , R 4 and R 5 each represent H or an alkyl group or the like, and R 1 , R 2 , R 4 and R 5 may be the same as or different from each other; X and Y each represents H, OH, OCH 3 or the like; h represents an integer of 1 to 3; p, n, m and q each represent 0 or an integer, and p, n, m and q are in no particular order; and (p + n + m + q) is an integer of 0 to 5,000.
专利号:US-7329515-B2 优先权日:2003-04-21 标题 :Solid support for the synthesis of 3′-amino oligonucleotides 发明人:LEUCK MICHAEL; WOLTER ANDREAS 权利人:SIGMA ALDRICH CO 摘要:The present invention discloses novel methods and solid supports for the synthesis of 3′-amino oligonucleotides. The novel supports are based on an unsubstituted or ring-substituted hydroxymethylbenzoyl linker element wherein the hydroxymethyl group is esterified to a solid phase bound carboxylic acid and the carbonyl group is linked to an amino alcohol as an amide. Oligonucleotides are conveniently synthesized on the novel supports with no modifications in the standard phosphoramidite synthesis scheme. The ester function of the support is cleaved under the alkaline deprotection conditions for oligonucleotides to provide a free hydroxymethyl group that aids in the release of the 3′-amino oligonucleotide products with a free amino group through neighbor group participation. The free amino group of the oligonucleotides is available for further conjugation reactions to haptens, reporter groups, surfaces or other small molecules or biomolecules. The methods provided are particularly mild, do not require any modifications in standard protocols for the synthesis and deprotection of oligonucleotides, provide the 3′-amino oligonucleotides free of side products and do not introduce chiral centers to the oligonucleotides.
专利号:US-2008032964-A1 优先权日:2006-04-10 标题:Process for the synthesis of azetidinone 发明人:KANSAL VINOD K; AHMAD SUHAIL; MARIAPPAN SHANMUGAVEL; TYAGI BHUPENDRA; PERLMAN NURIT; LE PAIH JACQUES; ZANOTTI-GEROSA ANTONIO 权利人:KANSAL VINOD K; AHMAD SUHAIL; MARIAPPAN SHANMUGAVEL; TYAGI BHUPENDRA; PERLMAN NURIT; LE PAIH JACQUES; ZANOTTI-GEROSA ANTONIO 摘要:Provided are intermediates useful for the synthesis of hydroxyl-alkyl substituted azetidinones, processes of their preparation, and processes for the synthesis of certain hydroxyl-alkyl substituted azetidinones. Also provided are processes for the synthesis of 1-(4-fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone, or ezetimibe.
专利号:US-6552213-B1 优先权日:2002-05-10 标 题:Stereoselective route to produce tris-O-substituted-(E)-1-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethene, an intermediate in the synthesis of trans-resveratrol 发明人:DESHPANDE PANDURANG BALWANT; SENTHILKUMAR UDAYAMPALAYAM PAL; ANDREW GNANAPRAKASAM 权利人:ORCHID CHEMICALS & PHARM LTD 摘要:The present invention relates to a new stereoselective method for the preparation of tris-O-substituted-(E)-1-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethene derivative of the formula (I) which is a key intermediate in the synthesis of trans-resveratrol (I, R2=R2=R3=H). The invention also provides a method for the exclusive synthesis of trans-isomer of compounds of formula (I) without any contamination of cis-isomer.
专利号:US-2024228455-A1 优先权日:2021-04-27 标 题 :Synthesis of cbn and cbnv 发明人:KAVARANA MALCOLM J 权利人:TEEWINOT LIFE SCIENCES CORP 摘要:The invention includes chemical synthesis for preparing cannabinol (CBN) and cannabinovarin (CBNV). The process is suitable for inter alia the large-scale synthesis of pharmaceutical grade CBN and CBNV.
专利号:US-2010016607-A1 优先权日:2006-12-11 标题:Process for the Synthesis of Highly Active Binary Metal Fluoride as a Fluorinating Agent for Aromatics 发明人:DOLBIER JR WILLIAM R; JANMANCHI KRISHNA MURTHY 权利人:UNIV FLORIDA 摘要:The subject invention relates to a process for the synthesis of highly active binary metal fluoride system for the fluorination of aromatic compounds. Fluorinated aromatic compounds are valuable synthons for the chemical synthesis of pharmaceutical drugs and novel polymers. Fluorobenzene is used to control carbon content in steel manufacturing, is an intermediate for pharmaceuticals, pesticides and other organic compounds. Fluorobenzene is typically produced by the reaction of aniline and sodium nitrite in the presence of hydrogen fluoride. The present invention relates to a process for the synthesis of highly active binary metal fluoride system consists of copper (II) fluoride and aluminum (III) fluoride for the fluorination of aromatic compounds in gas phase and recycling of the reagent, in situ, using O 2 and HF.
参考文献:10.1016/j.brainres.2010.02.024 摘要:Rui D, Yongjian Y. Aluminum chloride induced oxidative damage on cells derived from hippocampus and cortex of ICR mice. Brain Res. 2010 Apr 09;1324():96–102. doi: 10.1016/j.brainres.2010.02.024. 参考文献:10.1007/s11033-011-1158-7 摘要:Sun J, Peng RH, Xiong AS, Tian Y, Zhao W, Xu H, Liu DT, Chen JM, Yao QH. Secretory expression and characterization of a soluble laccase from the Ganoderma lucidum strain 7071-9 in Pichia pastoris. Mol Biol Rep. 2012 Apr;39(4):3807–14. doi: 10.1007/s11033-011-1158-7. 参考文献:10.1002/dev.20589 摘要:Xing R, Zhong Z, Ma H, Cui Y, Zheng Y, Xu S, Che Y. The impairment of one‐trial passive avoidance learning in chicks caused by prenatal aluminum exposure. Developmental Psychobiology. 2011 Jul 20;54(2):133–8. doi: 10.1002/dev.20589.