CAS: 874-63-5; 1-Methoxy-3,5-Dimethylbenzene

该化合物是一种替代芳香化合物,其特征是苯环3和5位置的甲基和甲氧功能组,这种结构具有独特的反应性和溶解性,使其成为有机合成,特别是制药,农用化学品和香味生产中的宝贵中间体.其电子富含芳香的系统有利于电活性替代反应,而甲基氧化合物组则能增强稳定性和进一步发挥功能.该化合物的明确界定的分子框架和一贯纯度确保研究和工业应用的可靠性能.由于其可预见行为和与一系列反应条件的兼容性,该化合物通常在精细化学合成中使用.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号108-68-9 3,5-二甲基苯酚 | CAS号74-88-4 碘甲烷 | CAS号77-78-1 硫酸二甲酯 | CAS号6981-15-3 2-chloro-5-meth... | CAS号108-67-8 均三甲苯 | CAS号100667-93-4 ethyl 2,6-dimet... | CAS号67-56-1 甲醇 | CAS号22445-41-6 3,5-二甲基-1-碘苯 | CAS号6267-34-1 2-溴-5-甲氧基-1,3-二甲苯 | CAS号616-38-6 碳酸二甲酯 | CAS号106116-42-1 1-溴甲基-3-甲氧基-5-甲基-苯 | CAS号6267-34-1 2-溴-5-甲氧基-1,3-二甲苯 | CAS号527-54-8 3,4,5-三甲基苯酚 | CAS号108-68-9 3,5-二甲基苯酚 | CAS号527-61-7 2,6-二甲基对苯醌 | CAS号46331-50-4 5-甲氧基间苯二甲酸 | CAS号21009-92-7 1-(2-methoxy-4,... | CAS号60999-76-0 1-(4-methoxy-2,... | CAS号18102-38-0 1-Methoxy-3,5-d... | CAS号61019-03-2 3,5-二甲基-4-硝基苯甲醚

合成工艺路线路线简述

    2'-甲氧基-4',6'-二甲基苯乙酮置于硫酸体系中,化学反应生成 3,5-二甲基苯甲醚
    参考文献:Al-Ka'Bi,Ja'Far; Gore,Peter H.; Moonga,Baljit,Journal Of Chemical Research,Miniprint,1986,# 7,P. 2201-2226
    标题:Al-Ka'Bi,Ja'Far; Gore,Peter H.; Moonga,Baljit,Journal Of Chemical Research,Miniprint,1986,# 7,P. 2201-2226

    海关参考信息

    专利信息


    专利号:WO-2004009574-A1
    优先权日:2002-07-22
    标 题 :Synthesis of discodermolide
    发明人:FLORENCE GORDON; KOCH GUIDO; LOISELEUR OLIVIER; MICKEL STUART JOHN; PATERSON IAN
    权利人:NOVARTIS AG; NOVARTIS PHARMA GMBH; UNIV CAMBRIDGE TECH; FLORENCE GORDON; KOCH GUIDO; LOISELEUR OLIVIER; MICKEL STUART JOHN; PATERSON IAN
    摘要:The invention relates to a process for preparing discodermolide, for preparing intermediates for the manufacture of discodermolide and discodermolide analogues and to the intermediates obtained during the process. Wherein the process proceeds via a tetraene of formula (IV).

    专利号:US-7329769-B2
    优先权日:2001-07-13
    标 题:Catalytic boronate ester synthesis from boron reagents and hydrocarbons
    发明人:SMITH III MILTON R
    权利人:UNIV MICHIGAN STATE
    摘要:A process for producing a ring-substituted arene borane which comprises reacting a ring-substituted arene with an HB organic compound in the presence of a catalytically effective amount of an iridium or rhodium complex with three or more substituents, excluding hydrogen, bonded to the iridium or rhodium and a phosphorus organic ligand, which is at least in part bonded to the iridium or rhodium, to form the ring-substituted arene borane. Also provided are catalytic compounds for catalyzing the process comprising an iridium or rhodium complex with three or substituents, excluding hydrogen, bonded to the iridium or rhodium and optionally, a phosphorus organic ligand, which is at least in part bonded to the iridium or rhodium.

    专利号:US-10253004-B2
    优先权日:2017-01-26
    标 题:Indanylaminopyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
    发明人:ECKHARDT MATTHIAS; WAGNER HOLGER; PETERS STEFAN
    权利人:BOEHRINGER INGELHEIM INT
    摘要:The present invention relates to compounds of formula I, n nwherein the groups R, R 1 , R 2 , R 3 , m and n are defined herein, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.

    专利号:US-2006030702-A1
    优先权日:2004-08-09
    标 题:Synthesis of metal cyanines

    专利号:US-9580409-B2
    优先权日:2011-11-07
    标 题:Modulators of opioid receptors and methods of use thereof
    发明人:MALCOLM SCOTT; BOWEN CARRIE; MELNICK LAURENCE; XIE LINGHONG
    权利人:SUNOVION PHARMACEUTICALS INC; SUNOVION PHARMACEUTICALS INC
    摘要:Provided herein are compounds and methods of synthesis thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as pain, neurological disorders, psychiatric disorders, and neuromuscular disorders. Compounds provided herein modulate the activity of opioid receptor (e.g., μ-opioid receptor) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.

    专利号:WO-2005026142-A2
    优先权日:2003-09-15
    标题:Synthesis of alpha-tocopheryl alkanoates and precursors thereof
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    合成参考文献


    摘要:Li, D.-D.; Wang, G.-W., Science of Synthesis: Catalytic Transformations via CH Activation, (2015) 2, 375.
    摘要:Pandey, G.; Laha, R., Science of Synthesis: Photocatalysis in Organic Synthesis, (2018) 1, 160.
    摘要:Clark, K. F.; Dimitrova, D.; Murphy, J. A., Science of Synthesis, (2020) , 69.
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