CAS: 90-02-8; Salicylaldehyde

• ⚠️危险化学品目录(2015年版) 急性毒性-经皮,类别3
• 英文名称Salicylaldehyde
• 中文名称2-羟基苯甲醛
• IUPAC名称Benzaldehyde, 2-hydroxy-
• 其它别名2-Formylphenol; 2-Hydroxybenzaldehyde; Salicylic aldehyde
• CAS编号90-02-8
• MFCD编号:MFCD00003317
• EINECS号:201-961-0
• 分子式:C7H6O2
• 分子量:122.12
• 产品CID: 2443908
• 产品分类香精与香料 → 合成香料 → 醛类香料

• 相似结构搜索
• InChIKey: SMQUZDBALVYZAC-UHFFFAOYSA-N
• InChI=1S/C7H6O2/c8-5-6-3-1-2-4-7(6)9/h1-5,9H…
• 计算化学: 氢键受体数2.0氢键供体数1.0可旋转键数1.0

物理性质

• 熔点1-2  °C(文献)
• 沸点197  °C(文献)
• 闪点170 °F
• 密度1.146 g/mL at 25 °C(文献)
• PH:6-8 (H2O, 20°C)Not applicable
• pKa:8.37(at 25°C)
• PSA:37.3
• LogP:1.2047
• 折射率n20/D 1.573(文献)
• 蒸汽压1 mm Hg ( 33 °C)
• 溶解性4.9G/l
• 敏感性对空气和光线敏感
• 外观形态透明黄色液体
• 储存条件-20°C
• 产品应用该品为香料和其他有机合成的中间体.我国GB2760-86规定为允许使用的食用香料,主要用以配制肉桂和坚果香精.
• 性质描述淡黄色到淡红色,澄清油状液体,有苦杏仁气味,工业品为淡黄色到淡红色.熔点-7°C,沸点196-197°C,闪点76°C.相对密度1.167(20/4°C),折光率1.5735.溶于乙醇,乙醚和苯,微溶于水.

MSDS等安全信息

• GHS象形图
• GHS符号GHS07;
  注释: Exclamation mark
• 危险类别急性毒性 类别4(经口)
  水生慢性毒性 类别2
  致突变性 类别2
  急性毒性 类别4(经皮)
  皮肤腐蚀/刺激 类别2
  严重眼刺激 类别2
  水生慢性毒性 类别3
  急性毒性 类别3(经皮)
  皮肤致敏 类别1
  特定目标器官毒性 - 单次接触 类别3
  STOT SE 2
  特定目标器官毒性-重复接触 类别2
  严重眼刺激 类别2A
  易燃液体 类别4
• 警示词Warning(警告)
• 危险描述H302 |吞咽有害.
  H411 |对水生生物有毒并具有长期持续影响.
  H341 |怀疑导致遗传缺陷.
  H312 |皮肤接触有害.
  H315 |造成皮肤刺激.
  H319 |造成严重眼刺激.
  H412 |对水生生物有害并具有长期持续影响.
  H311 |皮肤接触会中毒.
  H317 |可能引起皮肤过敏反应.
  H335 |可能引起呼吸道刺激.
  H371 |可能损害器官.
  H373 |长期或反复接触可能损害器官.
  H227 |可燃液体
• 防范说明P202-P273-P301+P312-P302+P352-P305+P351+P338-P308+P313
• 危险等级6.1(b)
• UN编号3082
• 危险品标志Xn,N
• 包装等级II
• 安全声明26-36/37-36/37/39-36-61-64-29/35
• 危险类别码21/22-36/38-68-36/37/38-20/21/22-51-36-51/53-22
• WGK Germany2

欧盟法规

上下游产品

合成工艺路线路线简述

• 合成目标产物 Salicylaldehyde 主要起始原料 Methanesulfonic Acid, 1,1,1-Trifluoro-, 2-Formylphenyl Ester
• 90-01-7 = 90-02-8
  反应条件:1.1 Reagents: Hydrogen Peroxide Catalysts: Manganese Oxide (Mn3O4),Poly(Vinyl Alcohol),4-[(9-Acridinylimino)Methyl]-2-Methoxyphenol (Cu Complex) Solvents: Water; 4 H,80 °C
  标题:High Catalytic Performance Of The First Electrospun Nano-Biohybrid,Mn3O4/copper Complex/polyvinyl Alcohol,From Amaranthus Spinosus Plant For Biomimetic Oxidation Reactions
  作者:Naeimi,Atena; Ekrami-Kakhki,Mehri-Saddat
  参考文献:Applied Organometallic Chemistry 日期:2020 卷标:34(4)]
  
  = 90-02-8
  反应条件:1.1 Reagents: Sodium Dodecyl Sulfate,Hydrogen Peroxide Catalysts: Ammonium Iodide Solvents: Water; Rt; 20 Min,Rt1.2 Reagents: Sodium Thiosulfate Solvents: Water; Rt
  标题:Mild,Efficient,And Greener Dethioacetalization Protocol Using 30% Hydrogen Peroxide In Catalytic Combination With Ammonium Iodide
  作者:Ganguly,Nemai C.; Mondal,Pallab
  参考文献:Synthetic Communications 日期:2011 卷标:41(16) 页码:2374-2384]
  
  119-36-8 = 90-02-8
  反应条件:1.1 Reagents: Hydrogen Catalysts: Alumina,Manganese Oxide (Mno)
  标题:Preparation Of Aromatic Aldehydes By Continuous Catalytic Hydrogenation Of Aromatic Acids Or Aromatic Esters
  参考文献:China]
  
  90-01-7 = 90-02-8
  反应条件:1.1 Catalysts: Tempo,2286259-65-0 Solvents: Acetonitrile; 2 H,30 °C
  标题:Base-Free Aerobic Oxidation Of Alcohols Over Copper-Based Complex Under Ambient Condition
  作者:Mei,Qingqing; Liu,Huizhen; Yang,Youdi; Liu,Hangyu; Li,Shaopeng; Et Al
  参考文献:Acs Sustainable Chemistry & Engineering 日期:2018 卷标:6(2) 页码:2362-2369]
  
  90-01-7 = 90-02-8
  反应条件:1.1 Reagents: Oxygen Catalysts: Tempo,Palladium,Copper Solvents: Toluene; Overnight,1 Atm,110 °C
  标题:Bimetallic Cu-Pd Nanoparticles Supported On Bio-Silica As An Efficient Catalyst For Selective Aerobic Oxidation Of Benzylic Alcohols
  作者:Buxaderas,Eduardo; Graziano-Mayer,Marilyn; Volpe,Maria Alicia; Radivoy,Gabriel
  参考文献:Synthesis 日期:2017 卷标:49(6) 页码:1387-1393]
  
  90-01-7 = 90-02-8
  反应条件:1.1 Reagents: Oxygen Catalysts: Titania Solvents: (Trifluoromethyl)Benzene; 30 Min,1 Atm,303 K; 6 H,1 Atm,303 K
  标题:Visible Light Induced Efficient Selective Oxidation Of Non-Activated Alcohols Over {001} Faceted Tio2 With Molecular Oxygen
  作者:Ghosh,Subhash Chandra; Vadakkekara,Raji; Biswas,Abulkalam; Sahoo,Tapan; Pal,Provas; Et Al
  参考文献:Chemistry - An Asian Journal 日期:2016 卷标:11(21) 页码:3084-3089]
  
  90-01-7 = 90-02-8
  反应条件:1.1 Catalysts: Tempo,Copper(4+),Bis(Acetonitrile)Tetraaqua[μ-[5-Phenyl-2,8-Di(2-Pyridinyl-Kn)Anthyri... Solvents: Toluene; 12 H,100 °C
  标题:Dicopper Complexes With Anthyridine-Based Ligands: Coordination And Catalytic Activity
  作者:Huang,Da-Wei; Liu,Yi-Hung; Peng,Shie-Ming; Liu,Shiuh-Tzung
  参考文献:Organometallics 日期:2016 卷标:35(2) 页码:151-158]
  
  9005-53-2 = 90-02-8 + 488-17-5 + 496-16-2 + 876-02-8 + 90-00-6 + 93-51-6 + 496-78-6 + 527-55-9 + 134-96-3 + 121-33-5 + 100-66-3
  反应条件:1.1 Catalysts: Choline Chloride,Imidazole; 150 °C
  标题:Insights Into Alkaline Choline Chloride-Based Deep Eutectic Solvents Pretreatment For Populus Deltoides: Lignin Structural Features And Modification Mechanism
  作者:Li,Haichao; Et Al
  参考文献:International Journal Of Biological Macromolecules 日期:2021 卷标:193 页码:319-327]
  
  = 90-02-8
  反应条件:1.1 Reagents: Tert-Butyllithium; 5 Min,-78 °C1.2 18 H,0 °C
  标题:Total Synthesis Of Palodesangren B Trimethyl Ether And D Dimethyl Ether Via A Late-Stage Formation Of 2H-Pyran-2-One Of The Tetrahydrobenzo[c]Pyranochromenone Core
  作者:Tangdenpaisal,Kassrin; Songthammawat,Poramate; Akkarasereenon,Kornkamon; Chuayboonsong,Kanokpish; Ruchirawat,Somsak; Et Al
  参考文献:Journal Of Organic Chemistry 日期:2019 卷标:84(21) 页码:13410-13429]
  
  90-01-7 = 90-02-8
  反应条件:1.1 Reagents: Hydrogen Peroxide Catalysts: Molybdenum (Silica-Coated Iron Oxide/pva Supported); 7 H,80 °C
  标题:First Electrospun Immobilized Molybdenum Complex On Bio Iron Oxide Nanofiber For Green Oxidation Of Alcohols
  作者:Noghi,Sedighe Abbaspour; Naeimi,Atena; Hamidian,Hooshang
  参考文献:Polymer 日期:2018 卷标:149 页码:229-237]
  
  84761-77-3 = 90-02-8
  反应条件:1.1 Reagents: Cesium Carbonate Solvents: Toluene; 15 H,80 °C1.2 Reagents: Ethyl Acetate,Ammonium Chloride Solvents: Water
  标题:Cesium Carbonate Mediated Aryl Triflate Esters' Deprotection
  作者:Green,Alice E.; Agouridas,Vangelis; Deniau,Eric
  参考文献:Tetrahedron Letters 日期:2013 卷标:54(51) 页码:7078-7079]
  
  90-01-7 = 90-02-8
  反应条件:1.1 Reagents: Hydrogen Peroxide Catalysts: 1H-Imidazolium,3-Butyl-1-Methyl-,Tetracosa-μ-Oxoundecaoxo[μ12-[phosphato(3-)-K... Solvents: Acetonitrile,Water; 2.5 H,Reflux
  标题:Selective Oxidation Of Alcohols To Aldehydes Using Inorganic-Organic Hybrid Catalyst Based On Zinc Substituted Polyoxometalate And Ionic Liquid
  作者:Nadealian,Zahra; Mirkhani,Valiollah; Yadollahi,Bahram; Moghadam,Majid; Tangestaninejad,Shahram; Et Al
  参考文献:Journal Of Coordination Chemistry 日期:2012 卷标:65(6) 页码:1071-1081]
  
  90-01-7 = 90-02-8
  反应条件:1.1 Reagents: Hydrogen Peroxide Catalysts: Iron Oxide (Fe3O4),Ruthenium (Complex With Salen-Modified Polymer),2-Propenoic Acid,2-Methyl-,Methyl Ester,Polymer With Diethenylbenzene And 2-O... (Salen-Modified,Metal Complex) Solvents: Methanol; 60 °C; 60 °C; 2.5 H,60 °C
  标题:Synthesis And Catalytic Study Of Magnetic Separable Catalyst: M(Salen)-Functionalized Fe3O4 Polymer Composite Materials (M = Ru(Iii),Cu(Ii),Fe(Iii))
  作者:Shen,Hao-Yu; Pan,Sheng-Dong; Fang,Fang; Shi,Jia
  参考文献:Advanced Materials Research (Zuerich 日期:2011 卷标:197 页码:197-198]
  
  94-67-7 = 90-02-8
  反应条件:1.1 Reagents: Sulfuric Acid,Thallium Nitrate Solvents: Methanol,Water; > 1 Min,Rt
  标题:Activation Of Iron(Iii) And Bismuth(Iii) Nitrates By Tungstophosphoric Acid. Solvent-Free Oxidative Deprotection Of Oximes To Carbonyl Compounds
  作者:Firouzabadi,Habib; Iranpoor,Nasser; Amani,Kamal
  参考文献:Synthetic Communications 日期:2004 卷标:34(19) 页码:3587-3593]
  
  90-01-7 = 90-02-8
  反应条件:1.1 Reagents: Oxygen Catalysts: Ruthenium,Chloronitrosyl[[2,2′-[(1,1,2,2-Tetramethyl-1,2-Ethanediyl)Bis[(Nitril... Solvents: Ethyl Acetate; 11 H,Rt
  标题:(No)Ru(Salen)-Catalyzed Aerobic Oxidation Of O-Hydroxybenzyl Alcohol Derivatives
  作者:Tashiro,Aya; Mitsuishi,Akimasa; Irie,Ryo; Katsuki,Tsutomu
  参考文献:Synlett 日期:2003 卷标:(12) 页码:1868-1870]
  
  116585-12-7 = 90-02-8
  反应条件:1.1 Reagents: Potassium Carbonate Solvents: Ethanol,Water
  标题:Mild Base Mediated Desilylation Of Various Phenolic Silyl Ethers
  作者:Wilson,Noel S.; Keay,Brian A.
  参考文献:Tetrahedron Letters 日期:1997 卷标:38(2) 页码:187-190]
  
  94-67-7 = 90-02-8 [标题:Reaction Conditions
  标题:Bis(2,2'-Bipyridyl)Copper(Ii) Permanganate (Bbcp): A Mild And Versatile Oxidant In Organic Synthesis
  作者:Firouzabadi,H.; Sardarian,A. R.; Naderi,M.; Vessal,B.
  参考文献:Tetrahedron 日期:1984 卷标:40(23) 页码:5001-4]
  
  6630-33-7 = 90-02-8
  反应条件:1.1 Reagents: Diisopropylethylamine,Water Catalysts: Nickel Sulfate (Niso4) (Reaction Products With Bipyridine Modified Psp Cysteine Mutants) Solvents: Dimethylformamide; 12 H,Ph 8.8,Rt
  标题:Biocatalytic Cross-Coupling Of Aryl Halides With A Genetically Engineered Photosensitizer Artificial Dehalogenase
  作者:Fu,Yu; Huang,Jian; Wu,Yuzhou; Liu,Xiaohong; Zhong,Fangrui; Et Al
  参考文献:Journal Of The American Chemical Society 日期:2021 卷标:143(2) 页码:617-622]
  
  5663-67-2 = 90-02-8
  反应条件:1.1 Catalysts: Ytterbium Chloride; 1 Min,70 °C; 1 Min,70 °C -> 120 °C
  标题:A Green,Solvent-Free,Microwave-Assisted,High-Yielding Ybcl3 Catalyzed Deprotection Of Thp/mom/ac/ts Ethers Of Chalcone Epoxide And 2'-Aminochalcone And Their Sequel Cyclization
  作者:Kumar,Sumit; Verma,Nishant; Parveen,Iram; Ahmed,Naseem
  参考文献:Journal Of Heterocyclic Chemistry 日期:2016 卷标:53(6) 页码:2111-2122]
  
  5533-04-0 = 90-02-8
  反应条件:1.1 Catalysts: β-Cyclodextrin Solvents: Water; 1 Min,Rt; 8 Min,60 °C
  标题:β-Cyclodextrin In Water: Highly Facile Biomimetic One Pot Deprotection Of Phenolic Thp/mom/ac/ts Ethers And Concomitant Regioselective Cyclization Of Chalcone Epoxides And 2'-Aminochalcones
  作者:Kumar,Sumit; Verma,Nishant; Ahmed,Naseem
  参考文献:Rsc Advances 日期:2015 卷标:5(103) 页码:85128-85138]
  
  90-01-7 = 90-02-8
  反应条件:1.1 Reagents: Oxygen Catalysts: Alumina,Ruthenium Hydroxide Solvents: Acetonitrile,Toluene; 30 Min,Rt; Rt -> 80 °C; 1 H,11 Bar,80 °C
  标题:Continuous Flow Aerobic Alcohol Oxidation Reactions Using A Heterogeneous Ru(Oh)X/al2O3 Catalyst
  作者:Mannel,David S.; Stahl,Shannon S.; Root,Thatcher W.
  参考文献:Organic Process Research & Development 日期:2014 卷标:18(11) 页码:1503-1508]
  
  = 90-02-8 [标题:Reaction Conditions
  标题:Reactions Of 1-(2-Alkoxyphenyl)Alkaniminyl Radicals
  作者:Leardini,Rino; Mcnab,Hamish; Minozzi,Matteo; Nanni,Daniele; Reed,David; Et Al
  参考文献:Journal Of The Chemical Society 日期:2001 卷标:(20) 页码:2704-2710

海关参考信息

• 2912110000-甲醛
  2912210000-苯甲醛
  2907121100-间甲酚
  2908199090-其他酚的卤化衍生物
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

其他信息查阅

• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
• ➥ Globally Harmonized System
• ➥ REACH监管