CAS: 133-32-4; Indole-3-Butyric Acid

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830-96-6 270074-53-8 1216408-71-7

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Ethyl 4-[4-(1H-Indol-3-yl)Butanoyl]Piperazine-1-Carboxylate置于水,Sodium Hydroxide体系中,化学反应生成3-吲哚丁酸
参考文献:1-取代-4-[4-(1H-吲哚-3-基)丁基]哌嗪的合成
标题:1-取代-4-[4-(1H-吲哚-3-基)丁基]哌嗪的合成
摘要:已经开发了用于制备在 1 位带有杂环和脂肪族取代基的各种 4-[4-(1 H-吲哚-3-基) 丁基] 哌嗪的便捷合成路线.在这项工作中,研究和评估了常见前体 4-[4-(1 H-Indol-3-yl) 丁基] 哌嗪的一些合成可能性.
Doi:10.3998/ark.5550190.P008.289

专利信息

专利号:US-2025042888-A1
优先权日:2021-11-26
标题 :A process for the preparation of indolmycin and derivatives thereof
发明人：GULAM DASTAGER SYED; SHYAM SAID MADHUKAR; KHAN ABUJANAID; ARVIND KULKARNI AMOL
权利人:COUNCIL OF SCIENT AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN
摘要:The present disclosure relates to a new, simple, two step synthesis of Indolmycin and its derivatives of formula (I), in 4-5 hours. Formula (I) wherein said process comprising the step of: 10 (a) reacting indole derivative with methyl magnesium bromide in a suitable solvent at a temperature in the range of 0-30° C. followed by adding ethyl epoxy butanone in a suitable solvent at −20° C. for a period of 1-2 hrs and maintaining the obtained reaction mixture for 1 hr at −20° C. to obtain a compound; and (b) passing the compound obtained at step a), base and N-methylated quinidine 15 through solid-solid continuous flow reactor for 1 minute to obtain the compound of formula (I).

专利号:US-2002055171-A1
优先权日:1998-05-27
标题 :Preparation of biologically active 3-methyleneoxindole and definition of its application in stimulation of plant growth and tissue repair
发明人：TULI VIRENDA KUMAR
摘要:Identification of the true nature and metabolic action of 3 -methyleneoxindole (MO), a naturally occurring catabolite of the plant auxin, indole- 3 -acetic acid (IAA). Description of the two novel methods of synthesis of MO which produce the pure, biologically active auxin compound of MO. Discovery and description of the causes for the erroneous classification of MO as an inert compound with no auxin activity. These findings and methods of synthesis correct the ubiquitous theoretical errors which have driven scientific investigation and plant science research of plant auxins for nearly forty years. n Researchers have failed to observe the auxin activity of MO because of the use of standard but incorrect synthetic techniques which have consistently produced impure forms of 3 -bromooxindole- 3 -acetic acid ( 3 -Brox), the synthetic precursor of MO. In addition, the use of dimethylsulfooxide as a solvent for MO has been identified as a major source of contamination of MO during synthesis. n This invention describes two novel methods for synthesizing (MO). By using purified MO and avoiding the use of dimethylsulfoxide, it was found that the resulting MO product to be 100 to 1,00 fold more effective than IAA in promoting rooting in plant cuttings; supporting tissue differentiation and growth in stage I, stage II and stage III media used for the micropropagation of explants; promoting the formation of callus tissue over wounded plant parts; and, stimulating the production of interstitial tissue between scion and rootstock to increase the success rate for grafting. Therefore, this invention identifies MO as the dominant auxin in shoot acceleration, root development, wound sealing and scion acceptance. n Finally, the correct pathway from IAA to MO is presented.

专利号:WO-2008150031-A1
优先权日:2007-06-08
标题:Inhibitor of biosynthesis of plant hormone auxin, chemical plant regulator comprising the inhibitor as active ingredient, herbicidal agent, and use thereof
发明人：SHIMADA YUKIHISA; GODA HIDEKI; TACHIKAWA TOMOE; ISHII TAKAHIRO; SOENO KAZUO; FUJIOKA SHOZO; ASAMI TADAO
权利人:RIKEN; SHIMADA YUKIHISA; GODA HIDEKI; TACHIKAWA TOMOE; ISHII TAKAHIRO; SOENO KAZUO; FUJIOKA SHOZO; ASAMI TADAO
摘要:The first object is to provide an inhibitor of the synthesis of endogenous auxin. The second object is to provide a plant growth inhibitor or a herbicidal agent utilizing the auxin biosynthesis inhibitor. Thus, disclosed are: a method for screening a candidate for an auxin biosynthesis inhibitor capable of inhibiting the expression of an auxin-inducible gene, by adding each of candidate compounds for the auxin inhibitor to a plant; a method for selecting a compound capable of actually inhibiting the auxin synthesis in a plant, by adding each of candidate compounds to the plant, disrupting the plant and then measuring the amount of endogenous auxin; and a method for selecting a compound capable of inhibiting the production of indolpyruvic acid in the presence of a tryptophan deaminase and tryptophan which are prepared in advance. More specifically disclosed are: an auxin biosynthesis inhibitor comprising AVG, AOA, AOIBA, L-AOPP or an analogue thereof; and a plant growth regulator or a herbicidal agent comprising the compound as an active ingredient.

专利号:US-9181559-B2
优先权日:2009-09-15
标题 :Generation of high polyhydroxybutyrate producing oilseeds
发明人：PATTERSON NII; TANG JIHONG; HAN JIXIANG; TAVVA VENKATA; HERTIG ANDREW; ZHANG ZHIGANG; RAMSEIER THOMAS MARTIN; BOHMERT-TATAREV KAREN; PEOPLES OLIVER P; SNELL KRISTI D
权利人:PATTERSON NII; TANG JIHONG; HAN JIXIANG; TAVVA VENKATA; HERTIG ANDREW; ZHANG ZHIGANG; RAMSEIER THOMAS MARTIN; BOHMERT-TATAREV KAREN; PEOPLES OLIVER P; SNELL KRISTI D; METABOLIX INC
摘要:Transgenic plants, plant material, plant cells, and genetic constructs for synthesis of biopolymers, for example polyhydroxyalkanoates (“PHAâ€?) are provided. In one embodiment, the transgenic plants synthesize polyhydroxybutyrate (“PHBâ€?). In one embodiment the transgenic plant encodes siRNA for one or more of the genes encoding enzymes for producing PHA. In a more preferred embodiment, the siRNA expression is under the control of an inducible regulatory element. In another embodiment, the transgenic plant contains transgenes that encode expression enzymes that will degrade the polymer. In a preferred embodiment, the expression of these enzymes is under the control of a germination specific, inducible, or minimal promoter. In another embodiment, the transgenic plant contains transgenes encoding enzymes that increase carbon flow for polymer synthesis. In a preferred embodiment, these transgenes encode enzymes that increase carbon flow in the Calvin Cycle.

专利号:US-11884772-B2
优先权日:2020-08-21
标题:Phenylphosphine oxide and oxygen stable epoxy polymers and methods of synthesis
发明人：FUCHS WITOLD K; WIGGINS JEFFREY
权利人:THE UNIV OF SOUTHERN MISSISSIPPI
摘要:A polymer formed of at least one phenylphosphine oxide functional epoxide crosslinked with at least one phenylphosphine oxide amine such that the polymer has phosphorous concentrations of at least about 8 percent by weight, at least about 8.5 percent by weight, or any value or range of values therebetween.

专利号:US-6264962-B1
优先权日:1997-12-19
标 题:Use of cinnamic acid or of at least one of its derivatives in a cosmetic composition
发明人：BRETON LIONEL; GIRERD FLORENCE; RENAULT BEATRICE
权利人:OREAL
摘要:The invention relates to the use of cinnamic acid, or of at least one of its derivatives, in a cosmetic composition as an agent for promoting the synthesis of the skin's total lipids. n The invention also relates to a cosmetic composition comprising an effective amount of cinnamic acid or of at least one of its derivatives.