CAS: 134451-94-8; N-Acetyl-L-Glucosamine

该化合物是甘蓝胺的单沙酸衍生物,其特点是C-2位置上有一个乙酰胺组,该化合物因其在合成甘蓝氨基甘油和其他生物活性聚氨酸盐中作为前体的作用,对甘蓝二甲胺-2-deoxy-L-glucopranose具有重大兴趣.其结构特征使其对研究酶学过程,例如涉及甘蓝盐和甘蓝基转移酶的过程很有价值.L的配置将其与更常见的D-glucosamine衍生物区分开来,为专门研究应用提供了独特的立体化学特性.它通常用于发展香气建筑块和用作调查碳水酸酯活性酶的基质.

英文名称N-Acetyl-L-Glucosamine
中文名称N-乙酰氨基葡萄糖
IUPAC名称N-((2S,3S,4R,5S)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl)acetamide
其它别名2-Acetamido-2-Desoxy-D-Glucopyranose; 2-Acetamido-2-Deoxy Glucopyranose; D-Glcnac; N-Acetyl-L-Glucosamine; N-[2,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3-Yl]Acetamide; N-[(2S,3S,4R,5S)-3,4,5,6-Tetrahydroxy-1-Oxohexan-2-Yl]Acetamide; L-Glucose, 2-(Acetylamino)-2-Deoxy-; 2-Acetamido-2-Deoxy-L-Glucopyranose
CAS编号134451-94-8
MFCD编号:MFCD00061615
EINECS号:231-368-2
分子式:C8H15NO6
分子量:221.21
产品CID: 525058
产品分类生物化工 → 糖类化合物 → 单糖

相似结构搜索
InChIKey: MBLBDJOUHNCFQT-KVPKETBZSA-N
InChI=1S/C8H15NO6/c1-4(12)9-5(2-10)7(14)8(15)6(13)3-11/h2,5-8,11,13-15H,3H2,1H3,(H,9,12)/t5-,6+,7+,8+/m1/s1…
计算化学: 氢键受体数7.0氢键供体数5.0可旋转键数7.0

物理性质

熔点211 °C (分解)(文献)
沸点636.4±55.0 °C at 760 mmHg
闪点338.7±31.5 °C
密度1.4±0.1 g/cm3
pKa:13.04±0.20(预测)
PSA:119.25
LogP:-2.68
折射率1.542
蒸汽压0.0±4.3 mmHg at 25°C
溶解性水: 50 mg/mL Colorless To Faint Yellow Solution, Clear To Very Slightly Hazy
外观形态白色至类白色粉末
储存条件−20°C
产品应用该化合物用于结肠清洗剂.

MSDS等安全信息

WGK Germany3

上下游产品

acetic anhydride N-[(2R,3R,4R,5R,6R)-2-((S)-2,3-Dihydroxy-propoxy)-5-hydroxy-6-hydroxymethyl-4-((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yl]-acetamide α-L-Fuc-(1-3)-β-D-GalNAc-(1-3)-β-D-Gal-(1-4)-β-D-Gal-(1-3)-D-GalNAc-ol 2-acetamido-2-deoxy-D-glucose2-acetamido-2-deoxy-D-galacticol trimethylsilyl ether of N-acetylgalactosamine anti-O-metyloxime trimethylsilyl ether of N-acetylgalactosamine syn-O-metyloxime N-[(1R,2R,3R,4R)-1-Formyl-2,4,5-trihydroxy-3-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-pentyl]-acetamide