专利号:US-2004092003-A1 优先权日:1997-03-19 标题:Multifunctional ceramic particles as solid supports for solid phase and combinatorial solid phase synthesis 发明人:BOSCHETTI EGISTO; KOCIS PETR 权利人:INVITROGEN CORP 摘要:Inert, thermally and mechanically stable porous ceramic solid phase supports for use in solid phase synthesis of molecules wherein the porous ceramic solid supports can be used under a wide variety of reaction conditions and in synthesis methods, including but not limited to organic, regular, multiple parallel, or combinatorial organic synthesis on a solid phase. Methods of using the porous ceramic solid supports for solid phase synthesis of molecules, for solid phase synthesis of polypeptides or peptidomimetics, for generating combinatorial libraries of linkers, and for combinatorial synthesis of compounds, including small molecules and aromatic and heteroaromatic compounds.
专利号:US-11008273-B2 优先权日:2019-02-15 标题 :Process for the manufacture of fluorinated benzenes and fluorinated benzophenones, and derivatives thereof 发明人:ZHOU CHANGYUE; DU HONGJUN; WU WENTING 权利人:FUJIAN YONGJING TECH CO LTD 摘要:The invention relates to a new process for the manufacture or synthesis, respectively, of fluorinated benzenes and fluorinated benzophenones, and derivatives thereof, in particular of fluorobenzenes and derivatives thereof. The present invention particularly pertains to a novel environmentally friendly process for the synthesis of fluorinated benzenes and benzophenones as raw materials for the manufacture of polyaryletherketones (PAEKs).
专利号:US-8513395-B2 优先权日:2005-06-15 标题:Method for the synthesis of anthocyanins 发明人:BAKSTAD EINAR 权利人:BAKSTAD EINAR; BIOSYNTH AS 摘要:The present invention relates to methods of preparing anthocyanins, and methods of preparing precursors of anthocyanins. The methods utilize a coupling reaction between a sugar and a suitable electrophilic precursor to form Eastern half intermediates that are then reacted with Western half intermediates to form the target anthocyanins. Some Eastern half intermediates and electrophilic precursors also form part of the invention.
专利号:US-2009111975-A1 优先权日:2005-06-15 标 题 :Method for the synthesis of anthocyanins
专利号:AU-2006258853-B2 优先权日:2005-06-15 标题 :Method for the synthesis of anthocyanins
专利号:US-10532991-B2 优先权日:2018-04-18 标题 :Method for preparing hispidulin and its derivatives 发明人:HUANG WEI-JAN; HSU KAI-CHENG; CHIOU LIH-CHU; CHEN LIANG-CHIEH; TSENG HUI-JU; FAN PI-CHUAN 权利人:UNIV TAIPEI MEDICAL 摘要:Provided is a method for preparing hispidulin or a derivative thereof. The method includes selective protection of trihydroxybenzaldehyde, followed by regioselective iodination, selective protection, Stille coupling, Baeyer-Villiger oxidation and basic hydrolysis to obtain a protected intermediate compound. Then, alkylation, Claisen-Schmidt condensation, cyclization and deprotection of the protected intermediate compound are performed to obtain hispidulin or the derivative thereof. The present disclosure provides an efficient method for total synthesis of hispidulin or the derivative thereof with concise reaction steps and high yield.
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