CAS: 35963-20-3; ((1R,4S)-7,7-Dimethyl-2-Oxobicyclo[2.2.1]Heptan-1-yl)Methanesulfonic Acid

相似化合物

3144-16-9 5872-08-2 5872-08-2

上下游产品

CAS号82509-30-6 (1R)-(-)-10-樟脑磺酸 铵盐 | CAS号5872-08-2 混旋樟脑磺酸 | CAS号76-26-6 [7,7-dimethyl-2... | CAS号7647-01-0 盐酸 | CAS号2935-35-5 (|S|)-(+)-α-苯甘氨酸 | CAS号357-57-3 马钱子碱 | CAS号94594-81-7 (S)-(+)-(2-丁烯酰)... | CAS号82509-30-6 (1R)-(-)-10-樟脑磺酸 铵盐 | CAS号107869-45-4 (+)-10-樟脑磺内酰亚胺 | CAS号104372-31-8 (1|R|)-(-)-(10-... | CAS号108448-77-7 (1R,2S)-(+)-2,1...

Voriconazole Camphor Sulfonate置于potassium Carbonate体系中,用 二氯甲烷,水,环己烷 用作溶剂,化学反应 8.0H,以93.2%的收率获得左旋樟脑磺酸
参考文献:一种伏立康唑拆分剂(R)-10-樟脑磺酸的回收方法
标题:一种伏立康唑拆分剂(R)-10-樟脑磺酸的回收方法
摘要:本发明公开了一种伏立康唑拆分剂(R)‑10‑樟脑磺酸的回收方法,包括以下步骤:(1)碱化处理:将伏立康唑樟脑磺酸盐溶于二氯甲烷和水的混合溶液中,再加入弱碱水溶液进行碱化处理,待分层后分离,留水层待用;(2)酸化处理:在步骤(1)所得的水层中加入强酸进行酸化处理,再浓缩蒸干得固体;将所得固体在加热条件下溶于有机溶剂,过滤,留滤液待用;(3)析晶处理:将环己烷加入到步骤(2)所得的滤液中,冷却析晶,析晶完成后进行抽滤,得到(R)‑10‑樟脑磺酸.伏立康唑拆分剂(R)‑10‑樟脑磺酸的回收方法具有分离简单,分离产物光学纯度高,经济,环保等优点.

专利信息

专利号:US-4110380-A
优先权日:1974-05-06
标题 :Asymmetric synthesis of organic compounds
发明人：HAJOS ZOLTAN GEORGE; PARRISH DAVID RICHARD
权利人:HOFFMANN LA ROCHE
摘要:Optically active organic compounds are prepared starting from optically inactive reactants by means of an optically active agent which influences the course of the reaction. In particular optically active compounds having a 'meso' type carbon atom undergo an intramolecular ring closure in the presence of an optically active agent to yield an optically active product having one additional ring. The present process is particularly useful in the preparation of optically active bicyclic diketones which are important intermediates in the total synthesis of steroids.

专利号:US-6472534-B2
优先权日:1999-10-21
标 题:Methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors
发明人：BORER BENNETT C; ZOOK SCOTT E; BUSSE JULIETTE K
权利人:AGOURON PHARMA
摘要:Methods for the preparation of chemical intermediates in the synthesis of HIV-protease inhibitors related to and including nelfinavir mesylate are disclosed. The method of this invention comprises converting tetrohydran derivatives into oxazolines to provide key reaction intermediates for the preparation of nelfinavir. Also disclosed is a method for the preparation of a chiral amino alcohol from an epoxy-tetrahydrofuran.

专利号:EP-2589587-A1
优先权日:2011-11-04
标题:Synthesis of nitrogen substituted cyclopropanes
发明人：RASPARINI MARCELLO; TADDEI MAURIZIO; CINI ELENA; MINELLI COSIMA; TURNER NICHOLAS; HUGENTOBLER KATHARINA GLORIA
权利人:CHEMO IBERICA SA
摘要:The invention is about a new synthetic pathway for the preparation of enantiomerically pure nitrogen substituted cyclopropanes, in particular the trans- cyclopropanamine ( 1 ), a key intermediate in the synthesis of Ticagrelor:n n The invention also relates to the processes for preparing said compounds or their salts and the use of said compounds as intermediates in preparing pharmaceutically active ingredients.

专利号:US-5597931-A
优先权日:1992-03-30
标 题:Total synthesis of taxol and analogues thereof
发明人：DANISHEFSKY SAMUEL J; MASTERS JOHN; YOUNG WENDY; LINK J THOMAS; ISAACS RICHARD; SNYDER LAWRENCE B
权利人:SLOAN KETTERING INST CANCER
摘要:The present invention provides three basic routes for the total synthesis of taxol having the structure: ##STR1## The present invention also provides the intermediates produced in the above processes, processes for synthesizing these intermediates as well as analogues of taxol and nortaxol.

专利号:US-5488116-A
优先权日:1992-03-30
标 题:Total synthesis of taxol and analogues thereof
发明人：DANISHEFSKY SAMUEL J; BORNMANN WILLIAM G; QUENEAU YVES; MAGEE THOMAS V; KROL WALTER J; MASTERS JOHN J; JUNG DAVID K
权利人:SLOAN KETTERING INST CANCER
摘要:The present invention provides three basic routes for the total synthesis of taxol having the structure: ##STR1## The present invention also provides the intermediates produced in the above processes, processes for synthesizing these intermediates as well as analogues of taxol and nortaxol.

专利号:US-11459427-B1
优先权日:2021-10-07
标题 :Synthesis of polyaniline or derivatives thereof
发明人：ALAMRY KHALID A; KHAN AJAHAR; ASIRI ABDULLAH MOHAMED
权利人:UNIV KING ABDULAZIZ
摘要:Provided are synthesis methods of polymerizing aniline or derivatives thereof. The production of polyaniline or polyaniline derivatives is controlled by the type of oxidant added in the reaction medium. The methods include the step of using a safe and environmentally friendly carbomethyl cellulose (CMC) or modified CMC as an oxidant in the polymerization reaction to produce polyaniline or aniline derivatives. Synthesis methods of producing O-CMC and O-CMC-S oxidants are also provided herein.