CAS: 671-35-2; 5-Fluoro-4-Hydroxypyrimidine

相似化合物

155-12-4 51-21-8 1683-86-9

上下游产品

CAS号347418-42-2 4-氯-5-氟嘧啶

氟乙酸乙酯,甲脒盐酸盐置于sodium Hydride,Sodium Ethanolate体系中,用 四氢呋喃,乙醇 作为反应溶剂,以7%的收率获得产物5-氟-4-羟基嘧啶
参考文献:Wo2006/72831
标题:Wo2006/72831

专利信息

专利号:US-2012282255-A1
优先权日:2011-04-07
标题 :Methods and compositions for the treatment of alcoholism and alcohol dependence
发明人：PLUCINSKI GREG
权利人:PLUCINSKI GREG
摘要:The present invention provides for compositions and methods for treating or preventing addictive and compulsive diseases and disorders, particular alcohol-related diseases and disorders, disclosed herein. The GLP activators of the present invention are effective against various alcohol and drug dependency diseases. In accordance with the invention, the present compositions and methods can be used to intercede upstream or downstream in the signal transduction cascade involved in GLP action to treat various alcohol and drug dependency diseases. In one embodiment, the synthesis or release of endogenous GLP can be stimulated. In another embodiment, the endogenous synthesis or release of another molecule active in the cascade downstream from GLP, (e.g., a molecule produced in response to GLP binding to a receptor), can be stimulated. Accordingly, the methods and compositions of the invention are useful for preventing, treating, diagnosing, or monitoring the progression various alcohol and drug dependency diseases disclosed herein.

专利号:ES-2580334-T3
优先权日:2014-01-13
标题 :Compositions of dendrimers, methods of synthesis, and their uses