CAS: 111-44-4; 2,2'-Dichlorodiethyl Ether

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CAS号628-89-7 2-(2-氯乙氧基)乙醇 | CAS号111-46-6 二乙二醇 | CAS号106-75-2 二乙二醇双氯甲酸酯 | CAS号107-07-3 2-氯乙醇 | CAS号54509-73-8 ethene | CAS号507-40-4 次氨酸叔丁基酯 | CAS号646-06-0 1,3-二氧戊环 | CAS号67-56-1 甲醇 | CAS号10288-17-2 2-chloroethyl n... | CAS号3970-21-6 2-甲氧基乙氧基甲基氯 | CAS号14187-32-7 二苯并-18-冠醚-6 | CAS号41758-00-3 1,2-bis[2-(2-ch... | CAS号111875-63-9 2-[2-(2-chloroe... | CAS号109-93-3 乙烯醚 | CAS号109-02-4 N-甲基吗啉 | CAS号123-91-1 1,4-二氧六环 | CAS号110-75-8 乙烯(2-氯乙基)醚 | CAS号75-07-0 乙醛 | CAS号34270-90-1 2-碘乙醚 | CAS号4319-49-7 N-氨基吗啉

2-氯乙氧基乙醇置于盐酸,硫酸,Zinc(II) Chloride体系中,化学反应生成二氯乙醚
参考文献:一种二氯乙醚和2-氯乙氧基乙醇的合成方法
标题:一种二氯乙醚和2-氯乙氧基乙醇的合成方法
摘要:本发明公开了一种二氯乙醚和2‑氯乙氧基乙醇的合成方法,属于有机合成领域.该方法包括:将摩尔比为0.8‑1.5:0.3二甘醇和催化剂加入双口烧瓶内,并使双口烧瓶的两个瓶口分别接分液漏斗和冷凝管;利用分液漏斗向双口烧瓶内滴加混合酸,在130oc‑170oc下进行反应,在反应过程中,利用冷凝管收集冷凝液;对冷凝液进行蒸馏,得到二氯乙醚;对双口烧瓶内剩余的液体进行抽滤,得到2‑氯乙氧基乙醇,其中,混合酸包括:质量比为25‑35:1的浓盐酸与浓硫酸.本发明实施例提供的合成方法不仅能够同时合成得到二氯乙醚和2‑氯乙氧基乙醇,而且,该方法反应简单可控,反应条件温和,原料安全且易得,使得两者的合成更加安全可控,成本更加低廉.

专利信息

专利号:US-5139940-A
优先权日:1989-10-26
标题 :Activation compounds and methods of synthesis of activation compounds
发明人：ISAACS STEPHEN T; CIMINO GEORGE D; METCHETTE KENNETH C; TESSMAN JOHN W
权利人:ISAACS STEPHEN T; CIMINO GOERGE D; METCHETTE KENNETH C; TESSMAN JOHN W
摘要:The invention is directed to isopsoralen compound compositions that contain a variety of substitutions which yet permit their binding to nucleic acid polymers. Reaction conditions that activate these bound isopsoralens results in covalent crosslinking to the nucleic acid polymers. The resultant complex is inhibited from being a template for the template-directed enzymatic synthesis of a complementary nucleic acid polymer. Beside the isopsoralens compositions, the invention includes their synthesis, the nucleic acid complex production and detection, and the above inhibitory method of use of the isopsoralens.

专利号:US-4339388-A
优先权日:1980-04-22
标题 :Synthesis of periplanone-B
发明人：STILL W CLARK
权利人:STILL W CLARK
摘要:A synthesis of periplanone-B, a female sex pheromone of the American cockroach, P. americana, is described. Novel compounds which are useful as intermediates in the synthesis of periplanone-B are described including the precursor alcohol, periplanol-B.

专利号:WO-8400363-A1
优先权日:1982-07-12
标题 :Synthesis of periplanone-b
发明人：STILL W CLARK
权利人:HERCULITE PRODUCTS INC
摘要:A synthesis of periplanone-B, a female sex pheromone of the American cockroach, P. americana. Novel compounds which are useful as intermediates in the synthesis of periplanone-B are described including the precursor alcohol, periplanol-B.

专利号:US-2009221568-A1
优先权日:2005-11-04
标题:Synthesis of Inhibitors of FtsZ
发明人：SHAW JARED; URGAONKAR SAMEER; RAYCHAUDHURI DEBABRATA; LA PIERRE HENRY
权利人:SHAW JARED; URGAONKAR SAMEER; RAYCHAUDHURI DEBABRATA; LA PIERRE HENRY
摘要:FtsZ, the bacterial analog of tubulin, is a promising new target for developing new antibiotics. It has been shown that polyphenols inhibit the GTPase activity of FtsZ, thereby inhibiting Z-ring formation during mitosis. The present invention provides novel polyphenols compounds, which can be accessed by the synthesis of dichamametin and 2′″-hydroxy-5″-benzylisouvarinol-B as described herein. These novel compounds are useful in treating infections, particularly infections caused by gram-positive organisms. Methods of preparing the inventive compounds are also provided. The compounds are prepared by the benzylation of pinocembrin or chrysin core structure. Pharmaceutical compositions and method of using the compounds to treat disease are also provided. These compounds may be screened for antimicrobial activity as well as other biological activities such as anti-neoplastic, anti-inflammatory, immunosuppressive, and cytotoxic activity.

专利号:US-10005720-B2
优先权日:2013-04-05
标题:Compounds useful for the treatment of metabolic disorders and synthesis of the same
发明人：SEXTON JONATHAN Z; BRENMAN JAY E; MUSSO DAVID L
权利人:NORTH CAROLINA CENTRAL UNIV; UNIV NORTH CAROLINA CHAPEL HILL
摘要:The present invention provides compounds of Formula (I): wherein variables X, Y, Z and R1 are as described herein. Some of the compounds described herein are glutamate dehydrogenase activators. The invention is also directed to pharmaceutical compositions comprising these compounds, uses of these compounds and compositions in the treatment of metabolic disorders as well as synthesis of the compounds.

专利号:US-3947517-A
优先权日:1969-06-12
标题:Stereoselective introduction of tetracyclines hydroxyl group at 12(a) position in synthesis of tetracyclines
发明人：MUXFELDT HANS H; MICHAEL JEFFREY
权利人:RESEARCH CORP
摘要:In the synthesis of tetracyclines, a critical step is the stereospecific or stereoselective introduction of a hydroxyl group at the C-12(a) position, a novel method for the introduction of this critical hydroxy group is disclosed. Additionally, synthetic procedures for obtaining tetracycline precursors are discussed.