CAS: 13608-87-2; 1-(2,3,4-Trichlorophenyl)Ethanone

该化合物是一种有机化合物,其特征是其氯酮功能组和三氯苯替代成分,一般视温度和纯度而定,看起来无色可粉黄黄色液体或固体,在苯环上存在三个氯原子,严重影响其化学特性,包括增加反应性和电益替代反应的可能性.该化合物一般在水中无法溶解,但在有机溶剂中可溶解,许多氯化有机化合物都常见.其分子结构有助于其在各个领域的潜在应用,包括制药和农用化学品.然而,由于氯的存在,它也可能表现出毒性和环境持久性,需要小心处理和处置.与许多氯化化合物一样,在与该物质合作或研究该物质时,必须考虑其安全数据,包括潜在的健康危害和环境影响.

结构式图片

相似化合物

56041-57-7 13061-28-4 2476-37-1

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

1-(3-amino-4-chloro-2-nitro-phenyl)-ethanone acetyl chloride 1,2,3-trichlorobenzene 3-amino-4-chloroacetophenone 2-bromo-1-(2,3,4-trichlorophenyl)ethanone 5-[1,2,4]triazol-1-yl-4-(2,3,4-trichloro-phenyl)-thiazol-2-ylamine 1-(2,3-dichloro-4-(2-isopropyl-phenylsulfanyl)-phenyl)-ethanone rac-1-(2,3,4-trichlorophenyl)ethanol

合成工艺路线路线简述

    3-氨基-4-氯苯乙酮置于盐酸,硝酸,Sodium Nitrite体系中,化学反应生成2',3',4'-三氯苯乙酮
    参考文献:53.五线谱.第九部分 制备约6:7-和7:8-双取代的4-羟基肉桂碱
    标题:53.五线谱.第九部分 制备约6:7-和7:8-双取代的4-羟基肉桂碱
    摘要:
    Doi:10.1039/jr9470000227

    海关参考信息

    专利信息


    专利号:US-2022145179-A1
    优先权日:2020-11-12
    标题 :Synthesis of aryl 1-(methoxymethyl) vinyl ketones and their use as inhibitors of mild steel corrosion
    发明人:MAZUMDER MOHAMMAD ABU JAFAR; ALI SHAIKH ASROF; ODEWUNMI NURUDEEN; ALHARBI BADER; ALJEABAN NORAH; CHEN TAO; BALHARTH SALEM
    权利人:SAUDI ARABIAN OIL CO; UNIV KING FAHD PET & MINERALS
    摘要:Methods for preparing alkenylphenone corrosion inhibiting compositions may include providing an arylacetone and reacting the arylacetone with formaldehyde in the presence of a strong base catalyst. Corrosion inhibiting compositions may include an alkenylphenone, which may be prepared by a method including providing an arylacetone and reacting the arylacetone with formaldehyde in the presence of a strong base catalyst. Methods of inhibiting corrosion of a steel surface of an oilfield equipment component may include contacting the steel surface with an aqueous solution comprising a corrosion inhibitor. The corrosion inhibitor may include a composition containing an alkenylphenone prepared by reacting an arylacetone with formaldehyde in the presence of a strong base catalyst.

    专利号:WO-2022104049-A1
    优先权日:2020-11-12
    标题 :Synthesis of aryl 1-(methoxymethyl) vinyl ketones and their use as inhibitors of mild steel corrosion

    专利号:US-10072009-B2
    优先权日:2014-10-21
    标 题 :N-substituted beta-carbolinium compounds as potent P-glycoprotein inducers
    发明人:BHARATE SANDIP; KUMAR AJAY; MANDA SUDHAKAR; JOSHI PRASHANT; BHARATE SONALI; VISHWAKARMA RAM
    权利人:COUNCIL SCIENT IND RES
    摘要:The present invention relates to the N-substituted beta-carbolinium compounds of general formula A and formulae I and II wherein, R 1 and R 2 groups are selected from halogens or trifluoromethyl; R 3 group is selected from hydrogen or methyl; Ar is selected from aryl and heteroaryl, X is selected from halogens; and R 1 and R 2 groups may be attached to any position on ring E. The present invention particularly relates to synthesis and p-glycoprotein induction activity of the N-substituted beta-carbolinium compounds. In addition, the invention relates to methods of using compounds for treating or preventing Alzheimer's disease.

    专利号:US-5734067-A
    优先权日:1994-09-28
    标题 :Anti-oxidative tricyclic, condensed heterocyclic compound
    发明人:JINNO SHUJI; KOGURE YASUYO; ONUKI HIROYUKI; OKITA TAKAAKI
    权利人:NIPPON SUISAN KAISHA LTD
    摘要:Providing a novel tricyclic, condensed heterocyclic compound having an anti-oxidative action and being promising for use in pharmaceutical agents, cosmetics, chemical products and the like. By chemical synthesis, a novel anti-oxidative, tricyclic, condensed heterocyclic compound represented by the following formula: ##STR1## (wherein X--Y represents CH 2 --Câ•?O, CH 2 --CH 2 or CHâ•?CH; Z represents O, S, or Sâ•?O; R 1 to R 8 represent independently those selected from the group consisting of hydrogen atom, a hydroxyl group, a halogen group, a lower alkyl group, a lower alkoxyl group, a lower alkyl ketone group and CF 3 ; and at least two of R 1 to R 4 are hydroxyl groups); and the salts thereof are provided. The compound has an anti-oxidative activity at the same degree as or higher than the activity of α-tocopherol, so the compound is promising as a therapeutic drug for a variety of diseases, such as cancer, arteriosclerosis, or liver diseases, in which it is believed that biological lipid peroxides may b involved.
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    主要参考文献

    [参考文献]: Young-Beom Ahn, Et Al. Co-Amendment With Halogenated Compounds Enhances Anaerobic Microbial Dechlorination Of 1,2,3,4-Tetrachlorodibenzo-P-Dioxin And 1,2,3,4-Tetrachlorodibenzofuran In Estuarine Sediments. Environ Toxicol Chem. 2005 Nov;24(11):2775-84.

    合成参考文献


    摘要:2024 Emergency Response Guidebook,
    摘要:National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
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