专利号:US-2022145179-A1 优先权日:2020-11-12 标题 :Synthesis of aryl 1-(methoxymethyl) vinyl ketones and their use as inhibitors of mild steel corrosion 发明人:MAZUMDER MOHAMMAD ABU JAFAR; ALI SHAIKH ASROF; ODEWUNMI NURUDEEN; ALHARBI BADER; ALJEABAN NORAH; CHEN TAO; BALHARTH SALEM 权利人:SAUDI ARABIAN OIL CO; UNIV KING FAHD PET & MINERALS 摘要:Methods for preparing alkenylphenone corrosion inhibiting compositions may include providing an arylacetone and reacting the arylacetone with formaldehyde in the presence of a strong base catalyst. Corrosion inhibiting compositions may include an alkenylphenone, which may be prepared by a method including providing an arylacetone and reacting the arylacetone with formaldehyde in the presence of a strong base catalyst. Methods of inhibiting corrosion of a steel surface of an oilfield equipment component may include contacting the steel surface with an aqueous solution comprising a corrosion inhibitor. The corrosion inhibitor may include a composition containing an alkenylphenone prepared by reacting an arylacetone with formaldehyde in the presence of a strong base catalyst.
专利号:WO-2022104049-A1 优先权日:2020-11-12 标题 :Synthesis of aryl 1-(methoxymethyl) vinyl ketones and their use as inhibitors of mild steel corrosion
专利号:US-10072009-B2 优先权日:2014-10-21 标 题 :N-substituted beta-carbolinium compounds as potent P-glycoprotein inducers 发明人:BHARATE SANDIP; KUMAR AJAY; MANDA SUDHAKAR; JOSHI PRASHANT; BHARATE SONALI; VISHWAKARMA RAM 权利人:COUNCIL SCIENT IND RES 摘要:The present invention relates to the N-substituted beta-carbolinium compounds of general formula A and formulae I and II wherein, R 1 and R 2 groups are selected from halogens or trifluoromethyl; R 3 group is selected from hydrogen or methyl; Ar is selected from aryl and heteroaryl, X is selected from halogens; and R 1 and R 2 groups may be attached to any position on ring E. The present invention particularly relates to synthesis and p-glycoprotein induction activity of the N-substituted beta-carbolinium compounds. In addition, the invention relates to methods of using compounds for treating or preventing Alzheimer's disease.
专利号:US-5734067-A 优先权日:1994-09-28 标题 :Anti-oxidative tricyclic, condensed heterocyclic compound 发明人:JINNO SHUJI; KOGURE YASUYO; ONUKI HIROYUKI; OKITA TAKAAKI 权利人:NIPPON SUISAN KAISHA LTD 摘要:Providing a novel tricyclic, condensed heterocyclic compound having an anti-oxidative action and being promising for use in pharmaceutical agents, cosmetics, chemical products and the like. By chemical synthesis, a novel anti-oxidative, tricyclic, condensed heterocyclic compound represented by the following formula: ##STR1## (wherein X--Y represents CH 2 --Câ•?O, CH 2 --CH 2 or CHâ•?CH; Z represents O, S, or Sâ•?O; R 1 to R 8 represent independently those selected from the group consisting of hydrogen atom, a hydroxyl group, a halogen group, a lower alkyl group, a lower alkoxyl group, a lower alkyl ketone group and CF 3 ; and at least two of R 1 to R 4 are hydroxyl groups); and the salts thereof are provided. The compound has an anti-oxidative activity at the same degree as or higher than the activity of α-tocopherol, so the compound is promising as a therapeutic drug for a variety of diseases, such as cancer, arteriosclerosis, or liver diseases, in which it is believed that biological lipid peroxides may b involved.
[参考文献]: Young-Beom Ahn, Et Al. Co-Amendment With Halogenated Compounds Enhances Anaerobic Microbial Dechlorination Of 1,2,3,4-Tetrachlorodibenzo-P-Dioxin And 1,2,3,4-Tetrachlorodibenzofuran In Estuarine Sediments. Environ Toxicol Chem. 2005 Nov;24(11):2775-84.
合成参考文献
摘要:2024 Emergency Response Guidebook, 摘要:National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.