CAS: 179463-17-3; (10R,12S)-N-((2R,6S,9S,11R,12S,14As,15S,20S,23S,25As)-20-((R)-3-Amino-1-Hydroxypropyl)-12-((2-Aminoethyl)Amino)-23-((1S,2S)-1,2-Dihydroxy-2-(4-Hydroxyphenyl)Ethyl)-2,11,15-Trihydroxy-6-((R)-1-Hydroxyethyl)-5,8,14,19,22,25-Hexaoxotetracosahydro-1H-Dipyrrol

上下游产品

acetic acid ethylenediamine 0pneum°Candin B0

反应生成醋酸卡泊芬净
参考文献:Process For Preparation Of Caspofungin Acetate And Intermediates
标题:Process For Preparation Of Caspofungin Acetate And Intermediates
摘要:本发明公开了一种从肺炎链霉菌素b0制备卡泊芬净及其中间体的方法.

专利信息

专利号:US-2024336559-A1
优先权日:2021-10-06
标 题 :Anti-fungals compounds targeting the synthesis of fungal sphingolipids
发明人：OJIMA IWAO; HARANAHALLI KRUPANANDAN; DEL POETA MAURIZIO; GARG ASHNA
权利人:UNIV NEW YORK STATE RES FOUND
摘要:The present invention provides a compound having the structure: n n n n n n n n n n n n wherein n R 3 , R 4 , R 5 , R 6 , and R 7 are each independently, H, halogen, CN, —CF 3 , —OCF 3 , —NO 2 , alkyl, alkenyl, alkynyl, aryl, heteroaryl, heterocycle, —OH, —OAc, —OR 13 , —COR 13 , —CH 2 OR 13 , —SH, —SR 13 , —SO 2 R 13 , —NH 2 , —NHR 13 , —NR 14 R 15 , —NHCOR 12 , or —CONR 14 R 15 ; n R 9 , R 10 , R 11 , and R 12 are each independently, H, CN, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl, heterocycloalkyl, —OAc, —COR 13 , —SH, —SR 13 , —SO 2 R 13 , —NH 2 , —NHR 13 , —NR 14 R 15 , —NHCOR 12 , or —CONR 14 R 15 ;n wherein each occurrence of R 13 is independently alkyl, alkenyl, alkynyl, aryl, or heteroaryl, wherein each occurrence of R 14 is independently —H, alkyl, alkenyl, alkynyl, aryl, or heteroaryl, wherein each occurrence of R 15 is independently —H, alkyl, alkenyl, alkynyl, aryl, or heteroaryl, n n wherein when R 14 is methyl, R 15 is not methyl; n wherein at least one of R 9 , R 10 , R 11 , and R 12 is not H; n wherein at least one of R 3 , R 4 , R 5 , R 6 , and R 7 is not H.

专利号:US-12325678-B2
优先权日:2017-06-16
标 题 :Anti-fungals compounds targeting the synthesis of fungal sphingolipids
发明人：OJIMA IWAO; DEL POETA MAURIZIO; LAZZARINI CRISTINA; HARANAHALLI KRUPANANDAN; SUN YI
权利人:UNIV NEW YORK STATE RES FOUND
摘要:The present invention provides a compound having the structure: n nand use of the compound for inhibiting the growth of or killing.

专利号:US-11858880-B2
优先权日:2017-06-16
标题 :Anti-fungals compounds targeting the synthesis of fungal sphingolipids

专利号:US-2022298103-A1
优先权日:2014-12-08
标 题 :Anti-fungals targeting the synthesis of fungal shingolipids

专利号:US-2022394973-A1
优先权日:2017-06-16
标 题:Anti-fungals compounds targeting the synthesis of fungal sphingolipids

专利号:US-11414378-B2
优先权日:2017-06-16
标题 :Anti-fungals compounds targeting the synthesis of fungal sphingolipids