Alkaline Earth Salt Of/the/ Methylsulfuric Acid 反应生成4-氨基吡唑 参考文献:Bertho; Nuessel,Justus Liebigs Annalen Der Chemie,1927,Vol. 457,P. 292 标题:Bertho; Nuessel,Justus Liebigs Annalen Der Chemie,1927,Vol. 457,P. 292
专利信息
专利号:US-7041833-B2 优先权日:2004-04-23 标 题:3-step synthesis of pyrazolotriazole couplers and coupler intermediates 发明人:MINEUR CATHERINE 权利人:EASTMAN KODAK CO 摘要:A process and intermediate useful for forming a 1H-Pyrazolo[1,5-b][1,2,4]triazole compounds comprise the step of reacting a 1,5-diaminopyrazole bearing a substituent, bonded to one and only one of the amine nitrogens by an acyl or thioacyl group, with a dehydrating agent in the presence of an aprotic solvent.
专利号:WO-2022256358-A1 优先权日:2021-06-03 标题 :Process for preparing medicaments 发明人:STUMPF ANDREAS; LAO DAVID; ANGELAUD REMY; MARX ANDREAS 权利人:GENENTECH INC; HOFFMANN LA ROCHE; HOFFMANN LA ROCHE 摘要:The present application affords an improved preparation of 3-(5-chloro-2-(difluoromethoxy)phenyl)-1H-pyrazol-4-amine hydrochloride qhich was a useful intermediate in the synthesis of JAK inhibitors.
专利号:US-2005240026-A1 优先权日:2004-04-23 标 题 :3-step synthesis of pyrazolotriazole couplers and coupler intermediates
专利号:WO-2008028776-A1 优先权日:2006-09-06 标题 :Agents containing bioquinones and specific emulsifiers 发明人:SCHULZE ZUR WIESCHE ERIK; SCHEUNEMANN VOLKER; POPPE ELISABETH; WELSS THOMAS; GIESEN MELANIE 权利人:HENKEL KGAA; SCHULZE ZUR WIESCHE ERIK; SCHEUNEMANN VOLKER; POPPE ELISABETH; WELSS THOMAS; GIESEN MELANIE 摘要:The invention relates to cosmetic agents, in particular hair treatment agents, containing at least one specific emulsifier and at least one bioquinone. Treating the hair with said agents activates the keratin synthesis of hair keratin that declines with age.
专利号:US-11312722-B2 优先权日:2019-05-08 标 题:Hsp90 inhibitors and uses thereof 发明人:BROWN LAUREN ELAINE; HUANG DAVID S; COWEN LEAH E; WHITESELL LUKE; MARCYK PAUL 权利人:UNIV BOSTON; GOVERNING COUNCIL UNIV TORONTO 摘要:Herein is described the design and synthesis of resorcylate aminopyrazole compounds. These compounds show broad, potent and fungal-selective Hsp90 inhibitory activity. These compounds also find use in treating Hsp90 related diseases.
专利号:US-11773130-B2 优先权日:2018-12-19 标 题 :3′ protected nucleotides 发明人:BERGMANN FRANK; CRISALLI PETER; HEINDL DIETER; KHAKSHOOR OMID; TAING MENG 权利人:ROCHE SEQUENCING SOLUTIONS INC 摘要:The present disclosure provides 3′ protected nucleotides, including those 3′ protected nucleotides having a detectable tag. Systems and methods of sequencing nucleic acids using the 3′ protected nucleotides are also disclosed, such as the sequencing of a nucleic acid using a nanopore or the sequencing of a nucleic acid via sequencing-by-synthesis.
[参考文献]: Bradley O Elmore, Et Al. Apolipoprotein B48, The Structural Component Of Chylomicrons, Is Sufficient To Antagonize Staphylococcus Aureus Quorum-Sensing. Plos One. 2015 May 5;10(5):E0125027.
合成参考文献
摘要:Farmaco, Edizione Scientifica., 25(592), 1970 []