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ethyl 5-phenyl-3-methyl-2-pentanoate (Z)-3-Methyl-5-phenyl-2-penten-1-ol (E)-3-methyl-5-phenyl-pent-2-en-1-ol 4-Phenyl-2-butanone mefanal 3-methyl-5-phenyl-1-pentanyl chloroacetate (+/-)-3-methyl-5-phenylpentyl palmitate (5-iodo-3-methylpentyl)benzene 合成工艺路线路线简述
- 合成目标产物 1-Pentanol, 3-Methyl-5-Phenyl 主要起始原料 2H-Pyran, 3,4-Dihydro-2-Phenyl-
- (文献来源)合成步骤主要原料 2H-Pyran, 3,4-Dihydro-2-Phenyl-
苄基丙酮置于lithium Aluminium Tetrahydride,Palladium 10% On Activated Carbon,氢气,Sodium Hydride体系中,用 四氢呋喃,甲醇 作为反应溶剂,化学反应 10.17H,反应生成 3-甲基-5-苯基戊醇
参考文献:空气稳定的 Pdi 二聚体实现远程功能化:以前所未有的速度获得氟化 1,1-二芳基烷烃
标题:空气稳定的 Pdi 二聚体实现远程功能化:以前所未有的速度获得氟化 1,1-二芳基烷烃
摘要:我们报告了在室温下在不到 10 分钟的反应时间内在长达 11 个碳的距离上进行的远程芳基化.空气稳定的 Pd 二聚体 [pd(μ-I)(Pcy 2 T Bu)] 2实现了前所未有的速度.
DOI:10.1002/anie.202113667
专利信息
专利号:US-2006223883-A1
优先权日:2005-04-02
标题 :Novel hydroxylated enantiomers of (-) 3a,6,6,9a-tetramethylperhydronaphtho[2,1-b]furan as perfuming agents derived from a fungal fermentation process.
发明人:RAHMAN ATTAUR; CHOUDHARY MOHAMMAD I; MUSHARRAF SYED G
权利人:RAHMAN ATTAUR; CHOUDHARY MOHAMMAD I; MUSHARRAF SYED G
摘要:(−) 3a,6,6,9a-tetramethylperhydronaphtho[2,1-b]furan (ambrox) is a strong aromatic compound used widely in a variety of perfumery applications and is highly prized for its musky odor. We report novel polar metabolites of (−)3a,6,6,9a-tetramethylperhydronaphtho[2,1-b]furan prepared by a novel process of microbial fermentation using a fungi, Fusarium lini , of unique structures that would be difficult to predict opening up the possibilities of their chemical synthesis. The polar metabolites discovered have stronger aromatic characteristics and offer a new highly prized odiferous characteristic quite different from that of the parent compound and thus can be used in the preparation of perfumes, odor-masking and other odor-management applications.
专利号:US-2012301956-A1
优先权日:2011-05-26
标 题:Novel hydroxylated enantiomers of (-) 3a,6,6,9a-tetramethylperhydronaphtho[2,1-b]furan as perfuming agents derived from a fungal fermentation process
发明人:RAHMAN ATTAUR; CHOUDHARY MOHAMMAD IQBAL; MUSHARRAF SYED GHULAM; SAMI AMTUL
权利人:RAHMAN ATTAUR; CHOUDHARY MOHAMMAD IQBAL; MUSHARRAF SYED GHULAM; SAMI AMTUL
摘要:(−)3a,6,6,9a-tetramethylperhydronaphtho[2,1-b]furan (ambrox) is a strong aromatic compound used widely in a variety of perfumery applications and is highly prized for its musky odor. We report novel polar metabolites of (−)3a,6,6,9a-tetramethylperhydronaphtho[2,1-b]furan prepared by a novel process of microbial fermentation using a fungi, Fusarium lini, of unique structures that would be difficult to predict opening up the possibilities of their chemical synthesis. The polar metabolites discovered have stronger aromatic characteristics and offer a new highly prized odiferous characteristic quite different from that of the parent compound and thus can be used in the preparation of perfumes, odor-masking and other odor-management applications.
专利号:CA-2640585-A1
优先权日:2003-02-05
标题 :Synthesis of 2-butyl-3-(2'-(1-trityl-1h-tetrazol-5-yl)biphenyl-4-yl)-1,3-diazaspirol{4,4}-non-ene-4-one
专利号:US-2025034074-A1
优先权日:2021-11-25
标题:Process for preparing a cyclic diene
发明人:JACOBY DENIS; CHAPPUIS SIMONE; KELLER FABRICE
权利人:FIRMENICH & CIE
摘要:The present invention relates to the field of organic synthesis and more specifically it concerns a process for preparing compound of formula (I) comprising the reaction of a compound of the formula (II) with a base having a boiling point superior to the boiling point of the compound of formula (I). Moreover, the compound of formula (I) and the compound of formula (II) are also part of the invention.
专利号:US-2024327367-A1
优先权日:2021-07-30
标 题 :Process for preparing a oxacylohexane or oxacylopentane derivative
发明人:DAPSENS PIERRE-YVES; VILCOQ LEA
权利人:FIRMENICH & CIE
摘要:The present invention relates to the field of organic synthesis and, more specifically, it concerns a process for the preparation of a cycloether of formula (I) comprising the cyclisation of compound of formula (II) performed in the presence of heterogenous acidic catalyst.
专利号:US-9156774-B2
优先权日:2011-03-25
标 题 :Carboxylic acid ester compound and method for producing same, and fragrance composition
发明人:KITAMURA MITSUHARU
权利人:KITAMURA MITSUHARU; MITSUBISHI GAS CHEMICAL CO
摘要:The present invention provides a novel carboxylic acid ester compound useful as a fragrance component or a material for a compound fragrance and a method for producing the same, and provides a fragrance composition including the carboxylic acid ester compound. The present invention also provides an acyl fluorides of a 2,4-dimethyl-bicyclo[2.2.2]octane compound and the esters thereof, useful as the raw materials (inclusive of the intermediates of organic synthesis), for example, for the medicines, agricultural chemicals, fragrances, functional resins, optical functional materials and electronic functional materials. The carboxylic acid ester compound of the present invention is a compound represented by the general formula (1). n n(In the formula, one of R 1 and R 2 is a methyl group and the other of R 1 and R 2 is —COOR, and R is an alkyl group having 1 to 4 carbon atoms.)