CAS: 703-23-1; 1-(2-Hydroxy-6-Methoxyphenyl)Ethanone

该化合物是一种有机化合物,其特点是芳香结构和功能组;其特点是苯丙基氢氧基组和附于苯环的甲氧基组,有助于其化学反应和潜在应用;丙酮的出现表明,它有一个可参与各种化学反应的氯酮功能组,包括核感激素添加和凝聚反应;这种复合体一般在室温下是固体的,由于其具有水分芳香结构,在有机溶剂中可能表现出溶解性;其氢氧基和甲氧氧基组可参与氢结合,影响其物理特性,如熔点和沸点等;此外,该化合物可能拥有生物活动,因此对诸如药用化学和材料科学等领域感兴趣.

英文名称1-(2-Hydroxy-6-Methoxyphenyl)Ethanone
中文名称2-羟基-6-甲氧基苯乙酮
IUPAC名称1-(2-hydroxy-6-methoxyphenyl)ethan-1-one
其它别名1-(2-羟基-6-甲氧基苯基)乙基-1-酮; 1-(2-Hydroxy-6-Methoxyphenyl)Ethanone
CAS编号703-23-1
MFCD编号:MFCD00008732
EINECS号:211-872-9
FDA UNII编号:M5VQG8968N
分子式:C9H10O3
分子量:166.17
产品CID: 1697392
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
InChIKey: UENLHUMCIOWYQN-UHFFFAOYSA-N
InChI=1S/C9H10O3/c1-6(10)9-7(11)4-3-5-8(9)12-2/h3-5,11H,1-2H3…
计算化学: 氢键受体数3.0氢键供体数1.0可旋转键数2.0

MSDS等安全信息

GHS象形图
GHS符号GHS07;
注释: Exclamation mark
危险类别特定目标器官毒性 - 单次接触类别3
皮肤腐蚀/刺激类别2
严重眼刺激类别2
严重眼刺激类别2A
警示词Warning(警告)
危险描述H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
防范说明P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
UN编号NONH for all modes of transport
危险品标志Xi
风险等级Irritant
安全声明26-37/39
危险类别码36/37/38
WGK Germany3

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

2,6-二甲氧基苯乙酮 2,6-Dimethoxyacetophenone 02/04/2040
2,6-二羟基苯乙酮 2,6-Dihydroxyacetophenone 699-83-2
2-乙酰基-3-甲氧基苯基二乙基氨基甲酸酯 Diethyl-Carbamic Acid 2-Acetyl-3-Methoxy-Phenyl Ester 211449-28-4
2-Hydroxy-6-Methoxy-A-Methylbenzenemethanol 1352515-27-5

合成工艺路线路线简述

合成目标产物 2'-Hydroxy-6'-Methoxyacetophenone 主要起始原料 2',6'-Dihydroxyacetophenone And Dimethyl Sulfate
(文献来源)合成步骤主要原料 2',6'-Dihydroxyacetophenone 和 Dimethyl Sulfate

8-乙酰基-7-羟基-4-甲基-2H-1-苯并吡喃-2-酮置于sodium Hydroxide体系中,化学反应生成 1-(2-羟基-6-甲氧基苯基)乙基-1-酮
参考文献:Limaye; Gangal,Rasayanam,1936,Vol. 1,P. 64,66
标题:Limaye; Gangal,Rasayanam,1936,Vol. 1,P. 64,66

海关参考信息

2902600000-乙苯
2905110000-甲醇
2907221000-对苯二酚
2912110000-甲醛
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-2022048879-A1
优先权日:2020-08-13
标题:Synthesis of small molecules inspired by Phomoxanthone A
发明人：ALI RAMEEZ; MATTSON ANITA
权利人:WORCESTER POLYTECH INST
摘要:Methods, compositions, and kits are provided for synthesizing bioactive chromane, the method including: constructing a tertiary ether stereocenter enantioselectively by catalyzed alkynylation of a substituted chromenone to obtain a chromanone; reducing alkyne and ketone in the chromanone to obtain a chroman; and converting ester to methyl group thereby obtaining chromane.

专利号:US-9168248-B2
优先权日:2009-02-17
标题:Spiro compounds useful as inhibitors of stearoyl-coenzyme A delta-9 desaturase
发明人：LACHANCE NICOLAS; LECLERC JEAN-PHILIPPE; LI CHUN SING; MORADEI OSCAR MIGUEL
权利人:LACHANCE NICOLAS; LECLERC JEAN-PHILIPPE; LI CHUN SING; MORADEI OSCAR MIGUEL; MERCK CANADA INC
摘要:Heteroaromatic compounds of structural formula (I) are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; and liver steatosis.

专利号:WO-2022036040-A1
优先权日:2020-08-13
标题 :Synthesis of small molecules inspired by phomoxanthone a

专利号:US-2017304168-A1
优先权日:2012-05-11
标题 :Phenyl ketone derivatives as self-tanning agents
发明人：CAROLA CHRISTOPHE
权利人:MERCK PATENT GMBH
摘要:The present invention relates to the use of phenyl ketone derivatives of the formula I for use as self-tanning substance or for increasing melanin synthesis, improving melanin transport and/or improving the distribution of melanin in suprabasal layers, and to preparations comprising these phenyl ketone derivatives.

专利号:RU-2195455-C2
优先权日:1995-04-11
标题 :Substituted 1-phenyl-3-carboxamides and their pharmaceutically acceptable salts, method of their synthesis, intermediate compounds and pharmaceutical composition based on thereof showing affinity to human neurotensin receptors