CAS: 823-96-1; Trimethylboroxine

上下游产品

trimethylborane water Dimethylborinsaeure-anhydrid dibromomethylboranetriisobutylborane (methyl)difluoroborane 1-methyl-1-vinylcyclohexane n-propylidenecyclohexane

三甲基硼置于boron Trioxide体系中,化学反应生成 三甲基环三硼氧烷
参考文献:Goubeau; Keller,Zeitschrift Fur Anorganische Und Allgemeine Chemie,1951,Vol. 267,P. 5,20
标题:Goubeau; Keller,Zeitschrift Fur Anorganische Und Allgemeine Chemie,1951,Vol. 267,P. 5,20

专利信息

专利号:US-7973171-B2
优先权日:2005-06-13
标题:Process for synthesis of dialkoxyorganoboranes
发明人：BURKHARDT ELIZABETH; ATKINS WILLIAM
权利人:BURKHARDT ELIZABETH; ATKINS WILLIAM
摘要:The invention relates to a process for the synthesis of dialkoxyorganoboranes, in particular to a process for the synthesis of dialkoxyorganoboranes by an ester exchange reaction. Moreover, the invention relates to a process for the synthesis of organo-oxazaborolidine catalysts (organo-CBS) and of trialkylboroxins. Furthermore, the invention relates to methods of using dialkoxyorganoboranes for the preparation of organo-CBS catalysts and in Suzuki-type coupling reactions.

专利号:US-8258299-B2
优先权日:2009-03-27
标题:Process for preparation of temsirolimus
发明人：LEE KWANG-CHUNG; LEE TING-HUEI; TUNG YEN-SHIH; KAO CHIA-CHEN; LEE TZU-AI
权利人:LEE KWANG-CHUNG; LEE TING-HUEI; TUNG YEN-SHIH; KAO CHIA-CHEN; LEE TZU-AI; CHUNGWA CHEMICAL SYNTHESIS & BIOTECH CO LTD
摘要:The present invention provides two synthetic routes for the preparation of Temsirolimus (compound 1b and analog of Temsirolimus 1a). The first route includes the synthesis of CCI-779 by directly reacting rapamycin (4b) or Prolyl-rapamycin (4a) with substituent-2,2-bis(methoxy) propionic acid anhydride(11) in the presence of an organic base, followed by deprotection to give CCI-779 or Proline CCI-779. The second route includes a process involving a reaction of rapamycin-OH-31-sily ether (4d) or Prolyl-rapamycin-OH-31-sily ether (4c) with substituent-2,2-bis(methoxy) propionic acid anhydride(11) in the presence of an organic base and followed by subsequent hydrolysis step to obtain the desired CCI-779 or Proline CCI-779. n Compound 11, as described in this invention, is stable at room temperature, cost effective and ease of processing.

专利号:US-6765117-B2
优先权日:1997-10-24
标题:Process for stereoselective synthesis of prostacyclin derivatives
发明人：MORIARTY ROBERT M; PENMASTA RAJU; GUO LIANG; RAO MUNAGALA S; STASZEWSKI JAMES P
权利人:UNITED THERAPEUTIC CORP
摘要:An improved method is described for making 9-deoxy-PGF 1 -type compounds. In contrast to the prior art, the method is stereoselective and requires fewer steps than the known methods for making these compounds. The invention also relates to novel intermediates prepared during the synthesis of the 9-deoxy-PGF 1 -type compounds.

专利号:US-2025115551-A1
优先权日:2023-10-03
标 题:Synthesis of ras inhibitors
发明人：LI YI; MENDOZA BENJAMIN; NAGANATHAN SRIRAM; WANG ROSS; YI YI; BALLMER STEVEN G; DAVIDSON JAMES; HUANG XIAOJUN
权利人:REVOLUTION MEDICINES INC
摘要:The present invention relates to Ras inhibitors, intermediates in the synthesis thereto, and methods for preparing the Ras inhibitors and the intermediates.

专利号:US-6096883-A
优先权日:1996-05-31
标 题 :3-hydroxy gamma-lactone based enantioselective synthesis of azetidinones
发明人：WU GEORGE G; CHEN XING; WONG YEE-SHING; SCHUMACHER DORIS P; STEINMAN MARTIN
权利人:SCHERING CORP
摘要:The invention relates to intermediates of the formulae ##STR1## said intermediates being useful in a process for producing a compound of the formula ##STR2## wherein Bn is benzyl and R 1 , 2 and R 3 are as defined in the specification,

专利号:WO-9842627-A1
优先权日:1997-03-20
标题 :Sol-gel synthesis of alkali-free borosilicate glass
发明人：VARMA KARIKATH SUKUMAR
权利人:PILKINGTON PLC; VARMA KARIKATH SUKUMAR
摘要:A method of producing metalloborates (including silicoborates) comprising reacting a trisubstituted boroxine with a tetrasubstituted orthosilicate or metal alkoxide in the substantial absence of hydroxyl groups to form a sol-gel so that the rate of reaction may be controlled and that the time taken for the reaction mixture to form a gel is substantially increased. The reaction may be carried out in the presence of a solvent and of a catalyst.