CAS: 112-77-6; Oleoyl Chloride

相似化合物

2541-61-9 53939-28-9 17746-05-3

上下游产品

CAS号112-80-1 油酸 | CAS号79-37-8 草酰氯 | CAS号56644-09-8 N-pyridin-3-ylo... | CAS号75-44-5 光气 | CAS号107743-37-3 N-Oleoyl-L-Serine | CAS号4303-70-2 Elaidamide | CAS号112-79-8 反油酸 | CAS号5431-33-4 丙烯酸-2,3-环氧丙酯十八烯酸 | CAS号33001-45-5 1,2-异亚丙基-3-油酰基-sn-甘油 | CAS号76-84-6 三苯基甲醇 | CAS号63057-13-6 N-methyl-N-(2-o... | CAS号55-21-0 苯甲酰胺 | CAS号14727-68-5 Z-N,N-二甲基-9-十八烯胺 | CAS号93-83-4 油酸二乙醇胺

油酸置于草酰氯体系中,用 二氯甲烷 用作溶剂,化学反应 3.0H,反应生成油酰氯
参考文献:Synthesis And Evaluation Of Fatty Acid Amides On The N-Oleoylethanolamide-Like Activation Of Peroxisome Proliferator Activated Receptor α
标题:Synthesis And Evaluation Of Fatty Acid Amides On The N-Oleoylethanolamide-Like Activation Of Peroxisome Proliferator Activated Receptor α
摘要:合成了一系列脂肪酸酰胺,并评估了它们在正常大鼠肝细胞系clone 9中对过氧化物酶体增殖物激活剂受体α(ppar-α)的激动活性.通过实时反转录聚合酶链反应(rt-Pcr)测定了ppar-α下游基因肉碱棕榈酰转移酶-1和线粒体3-羟基-3-甲基戊二酰辅酶a合酶的mrna,作为ppar-α激动活性的指标.我们合成了九种油酸酰胺.它们的ppar-α激动活性按递减顺序为n-油酸组胺(olha),N-油酸甘氨酸,油酰胺,N-油酸酪胺,N-油酸血清素和olvanil.最高活性出现在olha.我们还合成并评估了九种n-酰基组胺(n-Acyl-Has).其中,Olha,C16:0-Ha和c18:1δ9-Trans-Ha显示出相似的活性.由于饱和脂肪酸不同链长的活性在c16:0-Ha处达到峰值.Ppar-α拮抗剂gw6471抑制了olha和n-油酸乙醇酰胺(oea对ppar-α下游基因的诱导.这些数据表明n-酰基组胺可以被视为新的ppar-α激动剂.
Doi:10.1248/cpb.C14-00881

专利信息

专利号:US-2007049637-A1
优先权日:2003-11-12
标 题:Process for the synthesis of cationic lipids
发明人：DE FERRA LORENZO; ANIBALDI MAURO; AMMIRATI ETTORE
权利人:CHEMI SPA
摘要:A process for the synthesis of lipid cations having general formula (6): n n nin which: R 1 represents a lipophilic chain; R 2 , R 3 , R 4 , which are identical or different from one another, represent C 1 -C 10 alkyl, C 1 -C 10 alkenyl, or C 1 -C 10 alkynyl radicals, optionally containing hydroxyl, ether, halogen and acyloxy functions, and X − is an oxy-anion or a halide; in which a compound of formula (2), n n nin which R 5 and R 6 , which are identical or different from one another, represent a C 1 -C 5 acyl, a benzyl group or a diol-protective group, is reacted in an alcoholic solvent with from 1 to 6 equivalents of NR 2 R 3 R 4 .

专利号:US-7189849-B2
优先权日:1997-02-10
标 题:Synthesis of acyclic nucleoside derivatives
发明人：LEANNA M ROBERT; RASMUSSEN MICHAEL; HANNICK STEVEN M; TIEN JIEN-HEH J; LUKIN KIRILL A; TIAN ZHENPING; CHANG SOU-JEN; CURTY CYNTHIA B; NARAYANAN BIKSHANDARKOIL A; BELLETTINI JOHN; SHELAT BHADRA; SPITZ TIFFANY
权利人:MEDIVIR AB
摘要:Novel processes towards the synthesis of the antiviral valomaciclovir stearate in which an esterified guanine acetal is reduced to the corresponding alcohol, reacted with an activated amino acid and N-deprotected. The esterified guanine acetal is prepared from a 9-guanine derivative bearing an acyclic hydroxymethylbutylacetal. The processes are amendable to one-pot reactions.

专利号:EP-0542969-B1
优先权日:1991-06-04
标 题:Biodegradable particulate vector and method of synthesis
发明人：SAMAIN DANIEL; DE MIGUEL IGNACIO; MENIALI JAOUAD; IOUALALEN KARIM; DING LI; CERVILLA MONIQUE; RIEUMAJOU VALERIE; DELRIEU PASCAL; IMBERTIE LAURENT
权利人:BIOVECTOR THERAPEUTICS SA
摘要:A biodegradable particulate vector is disclosed and is characterized in that it comprises: a nucleus consisting of a cross-linked polysaccharide or oligosaccharide matrix to which ionic ligands are attached; a first semi-permeable lipid layer linked to the nucleus by covalent bonds; a second layer of amphiphilic compounds linked to the first lipid layer by hydrophobic interactions. A method for synthesis of said vector is also disclosed.

专利号:US-3959322-A
优先权日:1960-09-22
标 题:Synthesis of 13-alkyl-gon-4-ones
发明人：HUGHES GORDON ALAN; SMITH HERCHEL
权利人:SMITH HERCHEL
摘要:The preparation of 13-methylgon-4-enes and novel 13-polycarbonalkylgon-4-enes by a new total synthesis is described. 13-Alkylgon-4-enes having progestational, anabolic and androgenic activities are prepared by forming a tetracylic gonane structure unsaturated in the 1,3,5(10),9(11) and 14-positions, selectively reducing in the B- and C-rings, and converting the aromatic A-ring compounds so-produced to gon-4-enes by Birch reduction and hydrolysis.

专利号:US-2023111600-A1
优先权日:2019-12-17
标题 :Polymeric fatty acid compounds for the treatment of fibrous amino acid-based substrates, especially hair
发明人：WAGNER ROLAND; STREICHER KATHARINA; ROHMANN LAURA; WENSKE CHRISTIAN; HAVELI SHRUTISAGAR DATTATRAYA
权利人:MOMENTIVE PERFORMANCE MAT GMBH
摘要:The present invention is directed at mono-, di- or polyquaternary ammonium compounds of the formula (I) wherein x is 1 to 50, and F can be the same or different and is represented by the general formula (II) wherein at least one of the optionally substituted and optionally functional-group-containing hydrocarbon radicals R 1 , R 2 , R 3 , R 4 or R 5 contains at least one estolide moiety comprising two or more ester or amide moieties. The invention also relates to a process for the synthesis of such compounds, the use of the compounds in cosmetic formulations for skin and hair care, cosmetic compositions for the treatment of fibers, and compositions containing one or more of the compounds for the treatment of hair.

专利号:US-9487537-B2
优先权日:2013-06-12
标 题:Synthesis of isohexide dicarbamates and derivatives thereof
发明人：STENSRUD KENNETH
权利人:ARCHER DANIELS MIDLAND CO; ARCHER DANIELS MIDLAND CO
摘要:Dicarbamates of the reduction products of 2-hydroxymethyl-5-furfural (HMF) and a method of preparing the same are described. The method involves reacting a mixture of an isohexide and a cynate salt in a non-aqueous solvent, with a miscible acid having a pKa of about 3.7 or less. The dicarbamates of HMF-reduction products can serve as precursor materials from which various derivative compounds can be synthesized.