CAS: 172222-30-9; Benzylidenebis(Tricyclohexylphosphine)Dichlororuthenium

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CAS号536724-67-1 三环己基磷[3-苯基-1H吲哚... | CAS号254972-49-1 三环己基膦[1,3-双(2,4... | CAS号203714-71-0 二氯(邻异丙氧基苯基亚甲基)(...

三环己基膦,Dichloro(3-Phenyl-1H-Inden-1-Ylidene)Bis(Triphenylphosphine)Ruthenium(II) 反应生成苯基亚甲基双(三环己基磷)二氯化钌
参考文献:Ir-Thermographic Screening Of Thermoneutral Or Endothermic Transformations: The Ring-Closing Olefin Metathesis Reaction
标题:Ir-Thermographic Screening Of Thermoneutral Or Endothermic Transformations: The Ring-Closing Olefin Metathesis Reaction
摘要:
Doi:10.1002/(Sici)1521-3773(20000403)39:7<1236::Aid-Anie1236>3.0.Co;2-J

专利信息

专利号:US-7160517-B2
优先权日:2000-08-18
标题 :Apparatus and methods for the automated synthesis of oligosaccharides
发明人：SEEBERGER PETER H; PLANTE OBADIAH J
权利人:MASSACHUSETTS INST OF TECHNOLG
摘要:One aspect of the present invention relates to an apparatus for the efficient synthesis of oligosaccharides on a solid support, e.g., formed by subunit addition to terminal subunits immobilized on solid-phase particles. In certain embodiments, the apparatus of the present invention is used in combinatorial methods, e.g., as described herein, of synthesizing oligosaccharides.

专利号:US-7939679-B2
优先权日:2006-01-19
标题:Method for synthesis of ciguatoxin CTX1B and compounds useful for the synthesis of ciguatoxin CTX1B
发明人：HIRAMA MASAHIRO; INOUE MASAYUKI
权利人:JAPAN SCIENCE & TECH AGENCY
摘要:Disclosed is a method for total synthesis of CTX1B, which is developed for the synthesis of a ciguatoxin analogue such as CTX3C and enables the more efficient application of an established reaction to the total synthesis of CTC1B. More specifically, disclosed is a method for total synthesis of CTX1B comprising; an O.S-acetal formation for synthesizing a novel compound (3); a radical cyclization reaction for constructing a 9-membered ring formation reaction including a novel compound (6) through a novel compound (8) and yielding a compound (D); and a deprotection for yielding CTX1B. Also disclosed are novel compounds (1) to (8) which are particularly useful for synthesis of CTX1B and can be used for the synthesis of a ciguatoxin analogue.

专利号:US-6613910-B2
优先权日:2001-04-02
标题 :One-pot synthesis of group 8 transition metal carbene complexes useful as olefin metathesis catalysts
发明人：GRUBBS ROBERT H; MORGAN JOHN P; BENITEZ DIEGO; LOUIE JANIS
权利人:CALIFORNIA INST OF TECHN
摘要:The invention provides a novel method for synthesizing transition metal carbene complexes useful as olefin metathesis catalysts. The method is a convenient one-pot synthesis in which transition metal carbenes are prepared in high yield from readily available starting materials via a dihydrogen complex containing two different anionic ligands, preferably a phosphine and a heteroatom-stabilized carbene. The invention additionally provides a method for synthesizing precursors to carbene ligands useful, inter alia, in the aforementioned one-pot synthesis. The precursors are in the form of trichloromethyl adducts of the formula L 1 -CCl 3 , where L 1 is a heteroatom-stabilized carbene ligand, and are prepared by contacting an unsaturated, ionized analog of L-CCl 3 with a non-nucleophilic base in the presence of chloroform.

专利号:US-7034096-B2
优先权日:2002-02-19
标题:Ring-expansion of cyclic olefins metathesis reactions with an acyclic diene
发明人：CHOI TAE-LIM; LEE CHOON WOO; KIM HYUNJIN M; GRUBBS ROBERT H
权利人:CALIFORNIA INST OF TECHN
摘要:This invention relates generally to synthetic procedures that include the step of ring-opening metathesis of cyclic olefins and reaction with an acyclic diene co-reactant to produce olefin macrocycles by ring expansion, or alternatively. The ring expansion of the cyclic olefin is provided by three types of sequential olefin metathesis (ring-opening, cross, and ring-closing olefin metathesis). More particularly, the invention pertains to synthesis of olefin macrocycles via olefin metathesis reactions using a Group 8 transition metal complex as the metathesis catalyst. Macrocycles provided herein have a variety of uses in the pharmaceutical, biomedical, organic synthesis and chemical industries, such as the production of crown ethers that are useful as metal complexing species.

专利号:US-9403854-B2
优先权日:2001-03-30
标 题 :Cross-metathesis reaction of functionalized and substituted olefins using group 8 transition metal carbene complexes as metathesis catalysts
发明人：GRUBBS ROBERT H; CHATTERJEE ARNAB K; CHOI TAE-LIM; GOLDBERG STEVEN D; LOVE JENNIFER A; MORGAN JOHN P; SANDERS DANIEL P; SCHOLL MATTHIAS; TOSTE F DEAN; TRNKA TINA M
权利人:CALIFORNIA INST OF TECHN
摘要:The invention pertains to the use of Group 8 transition metal carbene complexes as catalysts for olefin cross-metathesis reactions. In particular, ruthenium and osmium alkylidene complexes substituted with an N-heterocyclic carbene ligand are used to catalyze cross-metathesis reactions to provide a variety of substituted and functionalized olefins, including phosphonate-substituted olefins, directly halogenated olefins, 1,1,2-trisubstituted olefins, and quaternary allylic olefins. The invention further provides a method for creating functional diversity using the aforementioned complexes to catalyze cross-metathesis reactions of a first olefinic reactant, which may or may not be substituted with a functional group, with each of a plurality of different olefinic reactants, which may or may not be substituted with functional groups, to give a plurality of structurally distinct olefinic products. The methodology of the invention is also useful in facilitating the stereoselective synthesis of 1,2-disubstituted olefins in the cis configuration.

专利号:US-6946533-B2
优先权日:2002-08-01
标 题 :Synthesis of macrocyclic polymers by ring insertion polymerization of cyclic olefin monomers
发明人：GRUBBS ROBERT; BIELAWSKI CHRIS; BENITEZ DIEGO
权利人:CALIFORNIA INST OF TECHN
摘要:A method for synthesizing cyclic polymers using transition metal alkylidene complexes as reaction catalysts is provided, wherein the complexes contain a cyclic group. Polymerization is carried out on the catalyst, using cyclic olefin monomers that undergo ring insertion polymerization, and no linear intermediates are generated. Following completion of polymerization, the cyclic polymer detaches from the complex via an intramolecular chain transfer reaction and the catalytic complex is regenerated. The invention also provides novel transition metal alkylidene complexes useful as catalysts in the aforementioned process, as well as novel cyclic hydrocarbons.