CAS: 446-51-5; 2-Fluorobenzyl Alcohol

上下游产品

o-fluorobenzyl bromide 2-Fluorotoluene 2-fluorobenzyl acetate ethanol o-fluorobenzyl bromide 2-fluorobenzyl N-succinimidyl carbonate 2-fluorobenzyl chloride 2-Fluorobenzaldehyde

邻氟苯甲酸置于cunninghamella Elegans Dsm1908体系中,用 N,N-二甲基甲酰胺 作为反应溶剂,化学反应生成 2-氟苄醇
参考文献:秀丽隐杆线虫和链霉菌的高效生物转化. Jcm9888选择性氟化苯甲酸反应生成相应的苯甲酰胺和苯甲醇
标题:秀丽隐杆线虫和链霉菌的高效生物转化. Jcm9888选择性氟化苯甲酸反应生成相应的苯甲酰胺和苯甲醇
摘要:在土壤细菌链霉菌的发酵中,邻位,间位和对位氟甲基和三氟甲基取代的苯甲酸有效转化为相应的苯甲酰胺. Jcm9888...
DOI:10.1080/10242422.2023.2267156

专利信息

专利号:US-6710208-B2
优先权日:1996-12-19
标题 :Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARMA INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

专利号:US-4255594-A
优先权日:1979-09-18
标题 :Hydrogenation of halogen-containing carboxylic anhydrides
发明人：NOVOTNY MIROSLAV
权利人:ALLIED CHEM
摘要:A process is described for the heterogeneous hydrogenation of haloalkyl, halocycloalkyl or haloaryl carboxylic anhydrides to the corresponding primary alcohols. In the haloalkyl or halocycloalkyl carboxylic anhydrides at least one halogen is in the alpha-position relative to the carboxylic anhydride grouping. The hydrogenation can be carried out in the liquid or vapor phase in the presence of a supported or unsupported catalyst comprising a member of the group consisting of rhodium, iridium, metal oxides thereof, or mixtures thereof. In the liquid phase, the hydrogenation can be carried out batchwise under mild conditions of temperature and pressure, preferably at about 50°-150° C. and about 5-15 atmospheres, in an atmosphere containing hydrogen gas. A preferred embodiment is the hydrogenation of trifluoroacetic anhydride in the liquid phase to 2,2,2-trifluoroethanol, said alcohol being useful as an intermediate in the synthesis of the anesthetic, isoflurane, CF 3 CHClOCHF 2 .

专利号:US-2004053999-A1
优先权日:1997-09-17
标题 :Novel compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-6225341-B1
优先权日:1995-02-27
标 题:Compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
权利人:GILEAD SCIENCES INC
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-7041830-B2
优先权日:2003-03-31
标 题 :Process for preparing (RS) 3-methyl-1-(2-piperidinyl phenyl) butyl amine
发明人：KALKOTE UTTAM RAMRAO; GURJAR MUKUND KESHAO; JOSHI SHREERANG VIDYADHAR; KADAM SURESH MAHADEV; MONDKAR HARISH KASHINATH
权利人:COUNCIL SCIENT IND RES
摘要:The Present invention relates to a process for the preparation of (RS) 3-methyl-1-(2-piperidinyl phenyl) butyl amine of formula 1. n n n n n n n n n n (RS) 3-Methyl-1-(2-piperidinyl phenyl butyl amine having formula 1 is an important key intermediate for the synthesis of repaglinide of formula 2 an oral hypoglycemic agent.

专利号:WO-9967192-A2
优先权日:1998-06-24
标 题 :PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDE, KETONE, OXIME, AMINE, HYDROXAMIC ACID AND α,β-UNSATURATED CARBOXYLIC ACID AND ALDEHYDE COMPOUNDS