CAS: 4769-96-4; 6-Nitro-1H-Indole

上下游产品

CAS号19727-83-4 6-硝基吲哚啉 | CAS号1245255-75-7 2-ethynyl-5-nit... | CAS号121-14-2 2,4-二硝基甲苯标准溶液 | CAS号4637-24-5 N,N-二甲基甲酰胺二甲基缩醛 | CAS号10242-00-9 6-硝基吲哚-2-甲酸 | CAS号354807-12-8 1-hydroxy-6-nit... | CAS号16792-45-3 6-硝基吲哚-2-甲酸乙酯 | CAS号134747-25-4 Ethyl 2-[(3-nit... | CAS号10242-03-2 6-硝基吲哚-3-羧酸 | CAS号315203-37-3 6-硝基-吲唑-3-甲醛 | CAS号219552-64-4 6-硝基-1H-吲哚-1-羧酸叔丁酯 | CAS号5429-56-1 2-乙酰氨基丙烯酸 | CAS号105902-18-9 Nα-acetyl-6-nit... | CAS号6954-87-6 6-硝基芦竹碱 | CAS号5318-27-4 6-氨基吲哚 | CAS号126807-09-8 3-溴-6-硝基-1H-吲哚 | CAS号10553-13-6 6-硝基吲哚-3-甲醛 | CAS号135855-62-8 1-甲基-6-氨基吲哚 | CAS号3433-54-3 6-硝基靛红

吲哚-3-甲酸乙酯置于喹啉,氢氧化钾,硝酸,溶剂黄146体系中,化学反应生成 6-硝基吲哚
参考文献:Majima; Kotake,Chemische Berichte,1930,Vol. 63,P. 2237,2243
标题:Majima; Kotake,Chemische Berichte,1930,Vol. 63,P. 2237,2243

专利信息

专利号:US-12195777-B2
优先权日:2018-02-02
标 题 :Polynucleotide synthesis method, kit and system
发明人：HERON ANDREW JOHN
权利人:OXFORD NANEPORE TECH PLC; OXFORD NANOPORE TECH PLC
摘要:The invention relates to new in vitro methods for synthesising a polymer, particularly a polynucleotide molecule, having a pre-defined sequence of units such as nucleotides. For synthesising a polynucleotide molecule the methods involve a process of extending a polynucleotide synthesis molecule with a transfer nucleotide. The methods additionally involve repeating the extension process multiple times to iteratively extend the polynucleotide molecule with multiple transfer nucleotides to generate a new polynucleotide molecule having a pre-defined nucleotide sequence. The invention also relates to in vitro methods of joining multiple synthetic polynucleotides following synthesis to form larger synthetic polynucleotides, as well as devices and systems for performing the extension, synthesis and assembly methods of the invention.

专利号:US-2022396818-A1
优先权日:2019-09-10
标 题:Polynucleotide synthesis method, kit and system
发明人：MILTON JOHN; NAYYAR SOBIA; RIEDL JAN; OGAKI RYOSUKE; WILKINSON MARC GEORGE
权利人:OXFORD NANOPORE TECH PLC
摘要:The invention relates to new methods for synthesising polynucleotide molecules according to a predefined nucleotide sequence. The invention also relates to methods for the assembly of synthetic polynucleotides following synthesis, as well as systems and kits for performing the synthesis and/or assembly methods.

专利号:US-12037636-B2
优先权日:2018-07-19
标题 :Polynucleotide synthesis method, kit and system
发明人：MILTON JOHN; NAYYAR SOBIA; RIEDL JAN; OGAKI RYOSUKE
权利人:OXFORD NANOPORE TECH PLC
摘要:The invention relates to new methods for synthesising polynucleotide molecules according to a predefined nucleotide sequence. The invention also relates to methods for the assembly of synthetic polynucleotides following synthesis, as well as systems and kits for performing the synthesis and/or assembly methods.

专利号:WO-2025003669-A1
优先权日:2023-06-27
标题 :Polynucleotide synthesis method, kit and system
发明人：CHAPMAN TARUN STEPHEN; CLARKE DAVID EDWARD; CLARKE JAMES ANTHONY; COOK IMOGEN HELEN; MÃœLLER CAROLIN ANNE; OGAKI RYOSUKE; WHITE JAMES PHILIP
权利人:OXFORD NANOPORE TECH PLC
摘要:The invention relates to new methods for synthesising polynucleotide molecules according to a predefined nucleotide sequence. The invention also relates to methods for the assembly of synthetic polynucleotides following synthesis.

专利号:US-2007264694-A1
优先权日:2006-04-07
标题 :Use of non-standard bases and proximity effects for gene assembly and conversion of non-standard bases to standard bases during dna synthesis
发明人：PRUDENT JAMES R
权利人:ERAGEN BIOSCIENCES INC
摘要:The present methods relate to generating nucleic acid molecules using non-natural nucleotides. In some methods, the nucleic acid molecules may be generated by hybridizing a plurality of oligonucleotides comprising one or more non-natural nucleotides and using a polymerase and/or a coupling agent to link the hybridized oligonucleotides. The methods also relate to the use of proximity effects to generate nucleic acid molecules using non-natural nucleotides. Furthermore, the methods relate to the use of at least one non-natural base in a DNA template in order to generate a replicate of the DNA template in which the non-natural base has been replaced with a natural base.

专利号:WO-2018145009-A1
优先权日:2017-02-06
标 题 :Dna-zyme based methods & compositions for treating huntington's disease
发明人：POURMOTABBED TAYEBEH; REINER ANTON
权利人:UNIV TENNESSEE RES FOUND
摘要:Provided herein are methods and compositions for treating Huntington's disease. For example, provided are compositions that include DNA oligonucleotides that have targeting specificity for RNA encoding mutant huntingtin protein. When introduced into a cell, the DNA oligonucleotides reduce expression of the mutant huntingtin protein in a cell. For example, the DNA oligonucleotide, functioning as an enzymatic DNA molecule (or DNAzyme), cleaves the RNA encoding the mutant mRNA protein, thereby rendering the mRNA incapable of expression. That is, the cleavage event renders the RNA non¬ functional and reduces or abrogates protein expression from that RNA. Hence, synthesis of the mutant huntingtin protein is selectively reduced or inhibited, in accordance with the methods and compositions described herein. By silencing or reducing the expression of the mutant huntingtin protein, the methods and compositions describe herein can be used to treat Huntington's disease, including adult and juvenile onset Huntington's disease.