CAS: 55357-38-5; 2-Hydroxy-N,N,N-Trimethylethanaminium 4-Methylbenzenesulfonate

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上下游产品

2-(N,N-dimethylamino)ethanol methyl p-toluene sulfonatedistearoylphosphatidylcholine . 1-O-Hexadecyl-2-O-benzylglycero-3-phosph°CholinRac. 1-O-Hexadecyl-2-O-benzylglycero-3-phosph°Cholin phosphoryl>-rac-glycerol1,2-di-O-hexadecyl-3-O-2-(trimethylamino)ethylphosphoryl-rac-glycerol 29H39N2O5PC29H39N2O5P

合成工艺路线路线简述

    2-[cyclohexylcarbamoyl(Nitroso)Amino]Ethyl-Trimethylazanium;4-Methylbenzenesulfonate 反应生成 甲苯磺酸胆碱
    参考文献:Belyaev,A. A.;Radina,L. B.;Novoselova,A. A.,Izv. An Cccp. Cep. Xim.,(1988) N 11,S. 2542-2545
    标题:Belyaev,A. A.;Radina,L. B.;Novoselova,A. A.,Izv. An Cccp. Cep. Xim.,(1988) N 11,S. 2542-2545

    海关参考信息

    专利信息


    专利号:US-8153615-B2
    优先权日:2005-06-10
    标 题:Synthesis of glycerolipid carbamates and dicarbamates and their use as an antitumor compounds
    发明人:BITTMAN ROBERT; BYUN HOE-SUP; ARTHUR GILBERT
    权利人:BITTMAN ROBERT; BYUN HOE-SUP; ARTHUR GILBERT
    摘要:The syntheses and in vitro antitumor properties of carbamate-containing, dicarbamate-containing, and ureido-containing phospholipid compounds that have an ether linkage at the C-1 position of a glycerol backbone, a carbamate, dicarbamate, or ureido moiety at the C-2 position of the glycerol backbone, and a phosphocholine, phosphonocholine, or glycoside moiety at the C-3 position of the glycerol backbone are described. The synthesis and antiproliferative activity of ether lipids with a naphthol moiety at the C-1 position are also described. These compounds were shown to be potent inhibitors of cancer cell growth. These compounds are useful for killing cancer cells and treating cancer.

    专利号:US-7687652-B2
    优先权日:2004-01-15
    标题:Sphingomyelin, intermediates thereof and methods for preparation of same
    发明人:ROCHLIN ELIMELECH; HILDESHEIM JEAN; BERLIN ALISA
    权利人:BIOLAB LTD
    摘要:Novel cyclic and acyclic oxazaphospholanes are described, as well as their use in the synthesis of sphingomyelin and sphingomyelin analogous. The production of synthetic sphingomyelins is also described. 2S, 3R stereoisomers of oxazaphospholanes and sphingomyelins, and synthetic methods for their preparation are described.

    专利号:US-8940907-B2
    优先权日:2009-11-05
    标 题:Synthesis of phosphoric esters
    发明人:GLUESENKAMP KARL HEINZ
    权利人:GLUESENKAMP KARL HEINZ; MERCK PATENT GMBH
    摘要:The present invention relates to a process for the preparation of phosphoric esters, and to selected compounds.

    专利号:US-11046640-B2
    优先权日:2015-03-30
    标题:Water-soluble L-DOPA esters
    发明人:TACK JOHANNES; WYRWA RALF; LAUBE THORSTEN; SCHNALBELRAUCH MATTHIAS; WEISSER JUERGEN; VOELKEL CHRISTOPH
    权利人:BERLIREM GMBH
    摘要:The present invention relates to novel compounds of the formula I, methods for their preparation and their use for treatment of diseases. The invention discloses the synthesis of levodopa (L-DOPA) esters by coupling polyhydroxy compounds or their derivatives to the L-DOPA carboxyl group. The synthesis allows to produce L-DOPA derivatives which are highly soluble in water as well as aqueous and biocompatible liquids and have an improved hydrolytic stability in water or aqueous and biocompatible media for an application over several days. The invention helps producing L-DOPA substances for applications in the fields of medicine, biology and medical engineering as well as in the pharmaceutical industry.

    专利号:US-6180664-B1
    优先权日:1996-10-10
    标题 :Pentaerythritol derivatives, their production and use and intermediates for their synthesis
    发明人:HESS ULRICH; WINDECK ANNE-KATRIN; BROSIG HOLGER
    权利人:ISIS PHARMA GMBH
    摘要:The invention describes novel compounds derived from pentaerythritol of general formula I, XIV, XVI, XIX and XXII, the substituents being as defined in the description, which can be used as pharmaceutical active substances, especially for the treatment of cardiovascular diseases.

    专利号:WO-2009056955-A1
    优先权日:2007-10-30
    标题 :Amine-bearing phospholipids (abps), their synthesis and use
    发明人:ZUMBUEHL ANDREAS
    权利人:UNIV BASEL; ZUMBUEHL ANDREAS
    摘要:Disclosed herein are amine-bearing phospholipids (ABP). The ABPs display many properties and functionalities of naturally occurring phospholipids, but also new properties and functionalities, such as the ability to polymerize while maintaining structural integrity, that may supplement or expand the functionalities of naturally occurring phospholipids.
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    合成参考文献


    摘要:Kleemann, A.; Engel, J.; Kutscher, B.; Reichert, D., Pharmaceutical Substances[Online], Thieme: Stuttgart, (2003).
    摘要:McKenna, C. E.; Kashemirov, B. A.; Błażewska, K. M., Science of Synthesis, (2009) 42, 812.
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