CAS: 106-54-7; P-Chlorothiophenol

上下游产品

(4-chloro-phenyl)-(2,4-dinitro-phenyl)-sulfide ethyl S-(4-chlorophenyl) thiolcarbonate (4-chlorphenyl)magnesium bromide 4-chlorobenzenesulfonyl chloride 2-[(4-chlorophenyl)sulfanyl]ethanamine -piperidinomethyl-sulfid4-Chlor-phenyl-piperidinomethyl-sulfid (4-chloro-phenylsulfanyl)-succinic acid S-(4-chlorophenyl) furan-2-carbothioate

1,4-二氯苯置于硫化氢体系中,化学反应生成4-氯苯硫酚
参考文献:一种氯代硫蒽酮的合成新方法
标题:一种氯代硫蒽酮的合成新方法
摘要:本发明公开了一种氯代硫蒽酮的合成新方法,属于化工技术领域.该方法包括如下步骤:首先将硫氢化钠溶液加入到硫化氢发生器中,再向硫化氢发生器中滴加酸,产生的气体被导入至预热后的管道反应器中;然后向管道反应器中泵入预热后的对二氯苯,对二氯苯与硫化氢气体发生反应,将反应产物冷却后得到液体和气体,液体经精馏提纯得巯基氯苯;其次,向烧瓶中加入反应溶剂和碱,搅拌,再加入巯基氯苯和邻氯苯甲酸进行回流反应,反应结束后经后处理得中间体2‑羧基‑4'‑氯二苯硫醚;最后将2‑羧基‑4'‑氯二苯硫醚加入至浓硫酸中进行分子内环合脱水反应,反应结束后经提纯得目标产品.本发明方法操作简便,反应条件温和,清洁环保,产品收率和纯度高.

专利信息

专利号:US-6815214-B2
优先权日:2000-12-29
标 题 :Pharmaceutical uses and synthesis of diketopiperazines
发明人：BOYCE JIM P; HOWBERT J JEFFRY; TABONE JOHN C
权利人:CELLTECH R & D INC
摘要:The synthesis of novel diketopiperazines, their use in inhibiting cellular events such as those involving NFK-α, NFK-β and in the treatment of inflammation events, a combinatorial library of diverse diketopiperazines and process for their synthesis as a library and as individual compounds. In particular novel diketopiperazines are disclosed including their synthesis and use in cellular events such as activation of the transcription factor, nuclear factor, TNF-α, TNF-β and also apoptosis.

专利号:US-7276637-B2
优先权日:2002-08-02
标题:Synthesis of cyclohexanone derivatives
发明人：BRANDS KAREL MARIE JOSEPH; DAVIES ANTONY JOHN; OAKLEY PAUL JOSEPH; SCOTT JEREMY PETER; SHAW DUNCAN EDWARD; TEALL MARTIN RICHARD
权利人:MERCK & CO INC
摘要:A novel process for preparing cyclohexanone derivatives of formula (I) n nis described. The products are useful as gamma secretase inhibitors, or as intermediates in the synthesis of other gamma secretase inhibitors.

专利号:US-5654412-A
优先权日:1996-05-29
标 题:Processes for the synthesis of sialyl Lewisx compounds
发明人：SRIVASTAVA OM; GREGSON JONATHAN M
权利人:GLYCOMED INC
摘要:Disclosed are processes for the chemical synthesis of sialyl Lewisx-Y compounds where Y is -OH, -NHR, -SH, -SR or -OR, and R is an aglycon of at least one carbon atom.

专利号:WO-9616071-A1
优先权日:1994-11-21
标题:PROCESSES FOR THE SYNTHESIS OF 3'-SUBSTITUTED LEWISx COMPOUNDS
发明人：SRIVASTAVA OM; IPPOLITO ROBERT; SRIVASTAVA GEETA; SZWEDA ROMAN; OHUCHI TOSHIO
权利人:GLYCOMED INC; SRIVASTAVA OM; IPPOLITO ROBERT; SRIVASTAVA GEETA; SZWEDA ROMAN; OHUCHI TOSHIO
摘要:Disclosed are processes for the chemical synthesis of 3'-substituted Lewis-OR compounds where R is an aglycon of at least one carbon atom. One particular compound prepared by the processes of this invention is 8-methoxycarbonyl-octyl-2-acetamido-3-O-( alpha -L-fucopyranosyl)-4-O-[3-O-sulfo- beta -D-galactopyranosyl]-2-deoxy- beta -D-glucopyranoside.

专利号:US-9908846-B2
优先权日:2014-02-21
标题:Composition, synthesis, and use of new arylsulfonyl isonitriles
发明人：FLEMING FRASER FERGUSSON; LUJAN MONTELONGO JESUS ARMANDO
权利人:DUQUESNE UNIV OF THE HOLY GHOST; UNIV HOLY GHOST DUQUESNE
摘要:This invention relates to novel isonitriles, including arylsulfonyl isonitriles, and methods for their synthesis. The isonitriles include a conjugated ring system. The structure is designed with the flexibility to have multiple substitution patterns. The isonitriles may be used in applications including, but not limited to, pharmaceutical compositions.

专利号:US-8710210-B2
优先权日:2010-06-30
标题:Method of using N-thio compounds for oligonucleotide synthesis
发明人：HE YIGANG; SOROKIN VICTOR; MAZUR WIESLAW ADAM
权利人:HE YIGANG; SOROKIN VICTOR; MAZUR WIESLAW ADAM; GIRINDUS AMERICA INC
摘要:A method for synthesizing an oligonucleotide which comprises using a sulfurizing agent of general formula (I) for sulfurizing at least one phosphorus internucleotide linkage of a precursor of the oligonucleotide, wherein R is an aryl group or a heteroaryl group, which is bonded to the S-atom through an annular carbon atom; and R 1 and R 2 are independently organic residues, preferably a C1-C20 hydrocarbon residue. The method may further comprise purifying the oligonucleotide. Also included is a process for the synthesis of the sulfurizing agent.