欧盟法规
ECHA物质C&L通报上下游产品
CAS号3013-27-2 3-氟-2-硝基甲苯合成工艺路线路线简述
- 合成目标产物 2-Fluoro-6-Methylaniline 主要起始原料 3-Fluoro-2-Nitrotoluene
- (文献来源)合成步骤主要原料 3-Fluoro-2-Nitrotoluene
3-氟-2-硝基甲苯置于乙醇,镍体系中,化学反应生成 2-氟-6-甲基苯胺
参考文献:Loefgren Et Al.,Acta Chemica Scandinavica (1947),1955,Vol. 9,P. 1079,1083
标题:Loefgren Et Al.,Acta Chemica Scandinavica (1947),1955,Vol. 9,P. 1079,1083
专利信息
专利号:US-10857530-B2
优先权日:2015-12-10
标题 :Olefin metathesis catalysts
发明人:JOHNS ADAM M; MONTGOMERY T PATRICK; AHMED TONIA S; GRUBBS ROBERT H; PEDERSON RICHARD L
权利人:UMICORE AG & CO KG; CALIFORNIA INST OF TECHN
摘要:This invention relates generally to metathesis catalysts and the use of such catalysts in the metathesis of olefins and olefin compounds, more particularly, in the use of such catalysts in Z and E selective olefin metathesis reactions. The invention has utility in the fields of organometallics and organic synthesis.
专利号:US-7157604-B2
优先权日:2001-08-13
标题:Selective estrogen receptor modulators
发明人:MENG DONGFANG; PARKER JR DANN LEROY; WILKENING ROBERT R; RATCLIFFE RONALD W
权利人:MERCK & CO INC
摘要:The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a variety of conditions related to estrogen functioning including: bone loss, bone fractures, osteoporosis, cartilage degeneration, endometriosis, uterine fibroid disease, hot flashes, increased levels of LDL cholesterol, cardiovascular disease, impairment of cognitive functioning, cerebral degenerative disorders, restenosis, gynecomastia, vascular smooth muscle cell proliferation, obesity, incontinence, and cancer, in particular of the breast, uterus and prostate.
专利号:EP-1339683-B1
优先权日:2000-11-27
标题 :Estrogen receptor modulators
发明人:WILKENING ROBERT R; PARKER DANN LEROY JR; WILDONGER KENNETH J; MENG DONGFANG; RATCLIFFE RONALD W
权利人:MERCK & CO INC
摘要:The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a variety of conditions related to estrogen functioning including: bone loss, bone fractures, osteoporosis, cartilage degeneration, endometriosis, uterine fibroid disease, hot flashes, increased levels of LDL cholesterol, cardiovascular disease, impairment of cognitive functioning, cerebral degenerative disorders, restinosis, gynacomastia, vascular smooth muscle cell proliferation, obesity, incontinence, and cancer, in particular of the breast, uterus and prostate.
专利号:US-4338318-A
优先权日:1979-03-23
标 题 :Novel compositions and methods
发明人:HENRICK CLIVE A; LABOVITZ JEFFREY N; FOX ROLAND T V; RATHMELL WILLIAM G; SHEPHARD MARGARET C
权利人:ZOECON CORP
摘要:Novel 1-substituted uracils, synthesis and intermediates therefor, and compositions for the control of pests.
专利号:US-4297297-A
优先权日:1979-03-23
标题 :α-Cyano-β-(substituted-anilino)-N-ethoxycarbonylacrylamide intermediates
发明人:HENRICK CLIVE A; LABOVITZ JEFFREY N; FOX ROLAND T V; RATHMELL WILLIAM G; SHEPHARD MARGARET C
权利人:ZOECON CORP
摘要:Novel 1-substituted uracils, synthesis and intermediates therefor, and compositions for the control of pests.
专利号:US-4266056-A
优先权日:1978-04-07
标 题 :Phenyl uracils
发明人:HENRICK CLIVE A; LABOVITZ JEFFREY N; FOX ROLAND T V; RATHMELL WILLIAM G; SHEPHARD MARGARET C
权利人:ZOECON CORP
摘要:Phenyl uracils, synthesis and intermediates therefor, and compositions for the control of pests, especially fungi and bacteria.