CAS: 112-37-8; Undecanoic Acid

该化合物是一种饱和脂肪酸,具有11碳链,通常用于工业和制药用途,其主要优点包括它因其中链长度和化学稳定性而成为香料,润滑剂和增塑剂合成的前体.复合物显示有机溶剂具有有利的溶解性,便于其在配方中使用.此外,在抗微生物应用中使用了非decanoic酸,利用其轻微的杀菌特性.它直接的衍生潜力使得能够生产酯和其他功能化化合物.酸的纯度和一致性使它成为需要精确化学中间体的研究和制造过程的可靠选择.

结构式图片

相似化合物

112-42-5 112-44-7 1731-86-8

欧盟法规

REACH注册ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号112-42-5 十一醇 | CAS号1427084-96-5 ethyl 4-hydroxy... | CAS号1119-87-5 1,2-十二烷二醇 | CAS号22202-65-9 9-十一炔酸 | CAS号112-38-9 十一烯酸 | CAS号109752-07-0 tridec-2-yn-1-y... | CAS号65423-21-4 4-Undecenoic acid | CAS号112-41-4 1-十二烯 | CAS号107399-10-0 undecanoyltrime... | CAS号43146-97-0 十一烷基醚 | CAS号10484-11-4 Pentyl undecanoate | CAS号1731-86-8 十一酸甲酯 | CAS号20690-63-5 ethenyl undecanoate | CAS号110-94-1 戊二酸 | CAS号110-15-6 琥珀酸; 丁二酸 | CAS号64-19-7 冰醋酸 | CAS号693-54-9 2-癸酮 | CAS号2623-84-9 2-bromoundecano... | CAS号112-31-2 癸醛

合成工艺路线路线简述

    十一烷醇置于氧气,Palladium Diacetate,Bis(3-Fluoropyridin-4-yl)Acetylene体系中,用 1,4-二氧六环 用作溶剂,120.0 °C,405.33 Kpa 条件下,反应生成十一烷酸
    参考文献:Mof 稳定的全氟钯笼催化脂肪醇无添加剂好氧氧化成酸
    标题:Mof 稳定的全氟钯笼催化脂肪醇无添加剂好氧氧化成酸
    摘要:已合成氟化吡啶-Pd 2+配位笼并在金属有机框架(mof)的通道内以原子分辨率表征,并在脂肪醇有氧氧化为羧酸的过程中用作催化剂,无需任何添加剂.这些结果说明了一个罕见的稳定全氟化阳离子金属配合物的例子,对未来催化有机金属配合物的设计具有潜在意义.
    Doi:10.1002/chem.202103781

    海关参考信息

    专利信息


    专利号:US-11548898-B2
    优先权日:2017-07-06
    标题 :Synthesis of halichondrins
    发明人:KISHI YOSHITO; AI YANRAN; YE NING; WANG QIAOYI; YAHATA KENZO; ISO Kentaro; NAINI SANTHOSH REDDY; YAMASHITA SHUJI; LEE JIHOON; OHASHI ISAO; FUKUYAMA TAKASHI
    权利人:HARVARD COLLEGE; EISAI R&D MAN CO LTD
    摘要:The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof. In particular, the present invention provides methods and compounds useful in the synthesis of compound of Formula (H3-A).

    专利号:WO-2025119975-A1
    优先权日:2023-12-04
    标 题:A method for synthesis of harmine
    发明人:HETT ROBERT; GRAB HANUSCH; LAGOUTTE ROMAN
    权利人:RECONNECT LABS AG
    摘要:The invention relates to a method of synthesis of a compound of formula (I), harmine, according to the method comprising a step of transforming the compound of formula (II), into the compound of formula (I). The invention further relates to a compound of formula (II), which is an intermediate in synthesis of harmine according to the present invention.

    专利号:US-2006287520-A1
    优先权日:2005-05-16
    标 题 :Synthesis of salinosporamide A and analogues thereof
    发明人:DANISHEFSKY SAMUEL J; ENDO ATSUSHI
    权利人:DANISHEFSKY SAMUEL J; ENDO ATSUSHI
    摘要:A novel synthesis of salinosporamide A is provided. Salinospoamide A as well as structurally related natural products, omuralide and lactacystin, have been shown to be proteasome inhibitors. Therefore, these compounds as well as analogues of these natural products may be useful in the treatment of proliferative diseases such as cancer, autoimmune diseases, diabetic retinopathy, etc. The invention provides for the synthesis of salinosporamide A as well as analogs thereof using a convenient point for derivatization of the bicyclic core. Pharmaceutical compositions and method of using the inventive compounds are also provided.

    专利号:US-9643915-B2
    优先权日:2013-03-15
    标题:Methods for the synthesis of sphingomyelins and dihydrosphingomyelins
    发明人:ONICIU DANIELA CARMEN; HECKHOFF STEFAN; OSWALD BENOIT; REBMANN PETER; PEER ANDREAS; GONZALEZ MIGUEL; SAUTER PATRIK
    权利人:CERENIS THERAPEUTICS HOLDING SA
    摘要:The present invention includes methods for the synthesis of sphingomyelins and dihydrosphingomyelins. The present invention also includes methods for the synthesis of sphingosines and dihydrosphingosines. The present invention further includes methods for the synthesis of ceramides and dihydroceramides.

    专利号:US-9708354-B2
    优先权日:2013-03-15
    标 题:Methods for the synthesis of sphingomyelins and dihydrosphingomyelins
    发明人:ONICIU DANIELA CARMEN; HECKHOFF STEFAN; OSWALD BENOIT; REBMANN PETER; PEER ANDREAS; GONZALEZ MIGUEL; SAUTER PATRIK
    权利人:CERENIS THERAPEUTICS HOLDING SA
    摘要:The present invention includes methods for the synthesis of sphingomyelins and dihydrosphingomyelins. The present invention also includes methods for the synthesis of sphingosines and dihydrosphingosines. The present invention further includes methods for the synthesis of ceramides and dihydroceramides.

    专利号:US-11542269-B2
    优先权日:2018-01-03
    标 题:Prins reaction and compounds useful in the synthesis of halichondrin macrolides and analogs thereof
    发明人:CHOI HYEONG-WOOK; FANG FRANCIS G
    权利人:EISAI R&D MAN CO LTD
    摘要:The invention provides methods utilizing Prins reaction in the preparation of compounds that may be useful as intermediates in the synthesis of halichondrin macrolides and analogs thereof. The invention also provides compounds that may be useful as intermediates in the synthesis of a halichondrin macrolides and methods for preparing the same.
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    主要参考文献


    1: Navarro-Peñalver M, Perez-Martinez MT, Gómez-Bueno M, García-Pavía P, Lupón-Rosés J, Roig-Minguell E, Comin-Colet J, Bayes-Genis A, Noguera JA, Pascual-Figal DA. Testosterone Replacement Therapy in Deficient Patients With Chronic Heart Failure: A Randomized Double-Blind Controlled Pilot Study. J Cardiovasc Pharmacol Ther. 2018 Jan
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    合成参考文献


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    参考文献:10.1021/ja203653w
    摘要:Pistorius D, Li Y, Mann S, Müller R. Unprecedented anthranilate priming involving two enzymes of the acyl adenylating superfamily in aurachin biosynthesis. J Am Chem Soc. 2011 Aug 17;133(32):12362–5. doi: 10.1021/ja203653w.
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