CAS: 2011-48-5; (4-Methoxybenzyl)Hydrazine Hydrochloride

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CAS号824-94-2 4-甲氧基苄氯

4-甲氧基氯苄置于盐酸,一水合肼体系中,用 乙醇 用作溶剂,化学反应生成(4-甲氧苯基)肼盐酸盐
参考文献:Anti-Hiv Pyrazole Derivatives
标题:Anti-Hiv Pyrazole Derivatives
摘要:本发明涵盖具有抗hiv活性的新型和已知吡唑衍生物,其制造方法,药用组合物以及在医学中使用此类化合物.特别是,式i的化合物是人类免疫缺陷病毒逆转录酶酶的抑制剂,该酶参与病毒复制.因此,本发明的这些化合物可优势用作hiv感染的治疗药物.

专利信息

专利号:US-6407103-B2
优先权日:1998-04-21
标 题:Indeno [1,2-c] pyrazol-4-ones and their uses
发明人：NUGIEL DAVID A; CARINI DAVID J; DI MEO SUSAN V; YUE EDDY W
权利人:BRISTOL MYERS SQUIBB PHARMA CO
摘要:The present invention relates to the synthesis of a new class of indeno[1,2-c]pyrazol-4-ones of formula (I):that are potent inhibitors of the class of enzymes known as cyclin dependent kinases, which relate to the catalytic subunits cdk1-9 and their regulatory subunits know as cyclins A-H.This invention also provides a novel method of treating cancer or other proliferative diseases by administering a therapeutically effective amount of one of these compounds or a pharmaceutically acceptable salt form thereof. Alternatively, one can treat cancer or other proliferative diseases by administering a therapeutically effective combination of one of the compounds of the present invention and one or more other known anti-cancer or anti-proliferative agents.

专利号:CN-116444436-A
优先权日:2023-03-08
标题 :Synthesis method of aminophenylpyrazole compound