CAS: 5988-19-2; (S)-2,6-Dioxohexahydropyrimidine-4-Carboxylic Acid

相似化合物

155-54-4 5988-53-4 103365-69-1

上下游产品

CAS号65-86-1 乳清酸 | CAS号65-86-1 乳清酸 | CAS号103300-85-2 (S)-BENZYL 1-ME... | CAS号103365-69-1 1-甲基-L-4,5-二氢乳清酸 | CAS号103300-84-1 (S)-六氢-2,6-二氧代-...

乳清酸 反应生成 L-氢化乳清酸
参考文献:Lieberman; Kornberg,1953,Vol. 12,P. 223,227
标题:Lieberman; Kornberg,1953,Vol. 12,P. 223,227

专利信息

专利号:WO-2018167780-A1
优先权日:2017-03-12
标题 :Methods of prognosing and treating cancer
发明人：EREZ AYELET; RUPPIN EYTAN; LEE JOO SANG; KARATHIA HIREN; HANNENHALLI SRIDHAR
权利人:YEDA RES & DEV; UNIV MARYLAND
摘要:Methods of treating cancer are provided. Accordingly there is provided a method of treating cancer in a subject in need thereof, the method comprising determining a shift from the urea cycle to pyrimidine synthesis in a cancerous cell of the subject as compared to a control sample; and treating the subject with an immune modulating agent when the shift is indicated. Also provided are methods of prognosing cancer and treating cancer according to the prognosis.

专利号:WO-2009045637-A9
优先权日:2007-08-10
标 题 :Methods for the synthesis of acrylic acid and derivatives from fumaric acid

专利号:US-12098218-B2
优先权日:2015-12-17
标题 :Process for the manufacture of degarelix and its intermediates
发明人：RICCI ANTONIO; ZANON JACOPO; CABRI WALTER; GURYANOV IVAN; ORLANDIN ANDREA; BIONDI BARBARA; FORMAGGIO FERNANDO; VISENTINI DARIO
权利人:FRESENIUS KABI IPSUM S R L
摘要:The present invention provides a manufacturing process for preparing a peptide, preferably a decapeptide, such as degarelix, by incorporating p-nitro-phenylalanin in the amino acid sequence preferably during stepwise solid phase synthesis, and converting these into the required amino acids Aph(Hor) and/or D-Aph(Cbm), preferably while attached to a solid phase. The invention further provides intermediates useful in the manufacturing process.

专利号:US-2018161300-A1
优先权日:2015-05-11
标题:Citrin inhibitors for the treatment of cancer
发明人：EREZ AYELET; RABINOVICH SHIRAN; SILBERMAN ALON; AGRON SHANI
权利人:YEDA RES & DEV; YEDA RES & DEV
摘要:Provided are methods, pharmaceutical compositions and kits for treating cancer in a subject in need thereof, by administering to the subject a therapeutically effective amount of an agent which downregulates a mitochondrial aspartate-dependent pyrimidine synthesis, thereby treating the cancer.

专利号:US-2017008828-A1
优先权日:2007-08-10
标题:Methods for the synthesis of olefins and derivatives

专利号:EP-2188243-A2
优先权日:2007-08-10
标题:Methods for the synthesis of acrylic acid and derivatives from fumaric acid